1,402 research outputs found
© Author(s) 2009. This work is distributed under the Creative Commons Attribution 3.0 License. Natural Hazards
Relationship between lightning and model simulated microphysical parameters over the central and eastern Mediterranea
A case of nonarteritic anterior ischemic optic neuropathy of a male with family history of the disease after receiving sildenafil
A 51-year-old male was referred to the University Eye Clinic of Ioannina with nonarteritic anterior ischemic optic neuropathy (NAION) 12 hours after receiving sildenafil citrate (Viagra®). Examination for possible risk factors revealed mild hypercholesterolemia. Family history showed that his father had suffered from bilateral NAION. Although a cause-and-effect relationship is difficult to prove, there are reports indicating an association between the use of erectile dysfunction agents and the development of NAION. Physicians might need to investigate the presence of family history of NAION among systemic or vascular predisposing risk factors before prescribing erectile dysfunction drugs
Relationship between lightning and model simulated microphysical parameters over the central and eastern Mediterranean
Aubert Marcel. Lejeaux (Jeanne). Sculpture religieuse (Bibliothèque catholique des sciences religieuses), 1934. In: Bulletin Monumental, tome 93, n°2, année 1934. pp. 267-268
Diagnosis and outcome of oesophageal Crohn's disease
BACKGROUND AND AIMS:
Crohn's disease (CD) can involve any part of the gastrointestinal tract. We aimed to characterize clinical, endoscopic, histologic features and treatment outcomes of CD patients with oesophageal involvement.
METHODS:
We collected cases through a retrospective multicentre European Crohn's and Colitis Organisation CONFER [COllaborative Network For Exceptionally Rare case reports] project. Clinical data were recorded in a standardized case report form.
RESULTS:
A total of 40 patients were reported [22 males, mean (±SD, range) age at oesophageal CD diagnosis: 25 (±13.3, 10-71) years and mean time of follow-up: 67 (±68.1, 3-240) months]. Oesophageal involvement was established at CD diagnosis in 26 patients (65%) and during follow-up in 14. CD was exclusively located in the oesophagus in 2 patients. Thirteen patients (32.2%) were asymptomatic at oesophageal disease diagnosis. Oesophageal strictures were present in 5 patients and fistulizing oesophageal disease in one. Eight patients exhibited granulomas on biopsies. Proton-pump inhibitors (PPIs) were administered in 37 patients (92.5%). Three patients underwent endoscopic dilation for symptomatic strictures and none oesophageal-related surgery. Diagnosis in pre-established CD resulted in treatment modifications in 9/14 patients. Clinical remission of oesophageal disease was seen in 33/40 patients (82.5%) after a mean time of 7 (±5.6, 1-18) months. Follow-up endoscopy was performed in 29/40 patients and 26/29 (89.7%) achieved mucosal healing.
CONCLUSION:
In this case series the endoscopic and histologic characteristics of isolated oesophageal CD were similar to those reported in other sites of involvement. Treatment was primarily conservative, with PPIs administered in the majority of patients and modifications in pre-existing IBD-related therapy occurring in two thirds of them. Clinical and endoscopic remission was achieved in more than 80% of the patients.info:eu-repo/semantics/publishedVersio
Binomial level densities
It is shown that nuclear level densities in a finite space are described by a
continuous binomial function, determined by the first three moments of the
Hamiltonian, and the dimensionality of the underlying vector space.
Experimental values for Mn, Fe, and Ni are very well
reproduced by the binomial form, which turns out to be almost perfectly
approximated by Bethe's formula with backshift. A proof is given that binomial
densities reproduce the low moments of Hamiltonians of any rank: A strong form
of the famous central limit result of Mon and French. Conditions under which
the proof may be extended to the full spectrum are examined.Comment: 4 pages 2 figures Second version (previous not totally superseeded
Sex differences in etiology and short-term outcome in young ischemic stroke patients receiving mechanical thrombectomy
BACKGROUND: Although there are well known sex differences in older patients with ischemic stroke receiving acute reperfusion treatments, there is paucity of data in younger patients. METHODS: We investigated sex-related differences in clinical presentation, stroke etiology and short-term outcomes in consecutive young patients with acute ischemic stroke (AIS) below the age of 50 years receiving mechanical thrombectomy (MT) between January 2011 and May 2021 in a tertiary stroke center. RESULTS: We identified a total of 202 young ischemic stroke patients with MT, with 51% being female. Young female AIS patients were significantly younger (39 ± 8 vs. 43 ± 7 years, p < 0.001), and presented with a trend for more severe stroke on admission (median NIHSS 12 vs. 9, p = 0.065), compared to males, respectively. Young female AIS patients had higher rates of embolic strokes of determined or undetermined sources in the anterior circulation, while young male AIS patients suffered more often strokes of arterio-arterial embolism. Complete reperfusion (TICI score 3) was achieved significantly less often in young female AIS patients (69% vs. 83%, p = 0.006), and in-hospital mortality was 2-times higher (5% vs. 2%, p = 0.271) compared to males. CONCLUSIONS: Young female AIS patients receiving MT have higher rates of severe embolic strokes and less often complete reperfusion due to different occlusion sites and stroke etiology compared to males
The D0 Run IIb Luminosity Measurement
An assessment of the recorded integrated luminosity is presented for data
collected with the D0 detector at the Fermilab Tevatron Collider from June 2006
to September 2011 (Run IIb). In addition, a measurement of the effective cross
section for inelastic interactions, also referred to as the luminosity
constant, is reported. This measurement incorporates new features that lead to
a substantial improvement in the precision of the result. A luminosity constant
of \sigma_{LM} = 48.3\pm1.9\pm0.6 mb is obtained, where the first uncertainty
is due to the accuracy of the inelastic cross section used by both CDF and D0,
and the second uncertainty is due to D0 sources. The recorded luminosity for
the highest E_T jet trigger is L_rec = 9.2 \pm 0.4 fb^{-1}, with a relative
uncertainty of 4.3%.Comment: 20 pages, 23 figure
A voxelized immersed boundary (VIB) finite element method for accurate and efficient blood flow simulation
We present an efficient and accurate immersed boundary (IB) finite element
(FE) method for internal flow problems with complex geometries (e.g., blood
flow in the vascular system). In this study, we use a voxelized flow domain
(discretized with hexahedral and tetrahedral elements) instead of a box domain,
which is frequently used in IB methods. The proposed method utilizes the
well-established incremental pressure correction scheme (IPCS) FE solver, and
the boundary condition-enforced IB (BCE-IB) method to numerically solve the
transient, incompressible Navier--Stokes flow equations. We verify the accuracy
of our numerical method using the analytical solution for the Poiseuille flow
in a cylinder, and the available experimental data (laser Doppler velocimetry)
for the flow in a three-dimensional 90{\deg} angle tube bend. We further
examine the accuracy and applicability of the proposed method by considering
flow within complex geometries, such as blood flow in aneurysmal vessels and
the aorta, flow configurations that would otherwise be difficult to solve by
most IB methods. Our method offers high accuracy, as demonstrated by the
verification examples, and high applicability, as demonstrated through the
solution of blood flow within complex geometry. The proposed method is
efficient, since it is as fast as the traditional finite element method used to
solve the Navier--Stokes flow equations, with a small overhead (not more than
5) due to the numerical solution of a linear system formulated for the IB
method.Comment: arXiv admin note: substantial text overlap with arXiv:2007.0208
Immediate post-operative effects of tracheotomy on respiratory function during mechanical ventilation
INTRODUCTION: Tracheotomy is widely performed in the intensive care unit after long-term oral intubation. The present study investigates the immediate influence of tracheotomy on respiratory mechanics and blood gases during mechanical ventilation. METHODS: Tracheotomy was performed in 32 orally intubated patients for 10.5 ± 4.66 days (all results are means ± standard deviations). Airway pressure, flow and arterial blood gases were recorded immediately before tracheotomy and half an hour afterwards. Respiratory system elastance (E(rs)), resistance (R(rs)) and end-expiratory pressure (EEP) were evaluated by multiple linear regression. Respiratory system reactance (X(rs)), impedance (Z(rs)) and phase angle (φ(rs)) were calculated from E(rs )and R(rs). Comparisons of the mechanical parameters, blood gases and pH were performed with the aid of the Wilcoxon signed-rank test (P = 0.05). RESULTS: E(rs )increased (7 ± 11.3%, P = 0.001), whereas R(rs )(-16 ± 18.4%, P = 0.0003), X(rs )(-6 ± 11.6%, P = 0.006) and φ (rs )(-14.3 ± 16.8%, P = <0.001) decreased immediately after tracheotomy. EEP, Z(rs), blood gases and pH did not change significantly. CONCLUSION: Lower R(rs )but also higher E(rs )were noted immediately after tracheotomy. The net effect is a non-significant change in the overall R(rs )(impedance) and the effectiveness of respiratory function. The extra dose of anaesthetics (beyond that used for sedation at the beginning of the procedure) or a higher FiO(2 )(fraction of inspired oxygen) during tracheotomy or aspiration could be related to the immediate elastance increase
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