3-Fluoro-N-(3-fluorobenzoyl)-N-(2-pyridyl)benzamide

The title compound, C19H12F2N2O2, a 2:1 product of the reaction of 3-fluorobenzoylchloride and 2-aminopyridine crystallizes with a disordered 3-fluorobenzene ring adopting two conformations [ratio of occupancies 0.959 (4):0.041 (4)]. In the crystal structure, there are no classical hydrogen bonds and interactions comprise C-H...O in the form 2(C-H)...O=C [with motif R21(5)]; C-H...[pi](arene) interactions are also present

Harnessing Documentaries for Social Change

This guide from the Citizen Engagement Lab is designed to help advocates and nonprofit organizations collaborate with documentary filmmakers to advance their causes and increase impact. It includes case studies, key strategies and tactics, and a companion FAQ to help advocates think through their own unique impact goals and methods

Assembling an isomer grid: the isomorphous 4-, 3- and 2-fluoro-N'-(4-pyridyl)benzamides

The three title isomers, 4-, (I), 3-, (II), and 2-fluoro-N'-(4-pyridyl)benzamide, (III), all C₁₂H₉FN₂O, crystallize in the P21/c space group (No. 14) with similar unit-cell parameters and are isomorphous and isostructural at the primary hydrogen-bonding level. An intramolecular C-H...O=C interaction is present in all three isomers [C...O = 2.8681 (17)-2.884 (2) Å and C-H...O117-118°], with an additional N-H...F [N...F = 2.7544 (15) Å] interaction in (III). Intermolecular amide-pyridine N-H...N hydrogen bonds link molecules into one-dimensional zigzag chains [graph set C(6)] along the [010] direction as the primary hydrogen bond [N...N = 3.022 (2), 3.049 (2) and 3.0213 (17) Å]. These are augmented in (I) by C-H...π(arene) and cyclic C-F...π(arene) contacts about inversion centres, in (II) by C-F...F-C interactions [C...F = 3.037 (2) Å] and weaker C-H...π(arene)/C-H...F contacts, and in (III) by C-H...π(arene) and C=O...O=C interactions, linking the alternating chains into two-dimensional sheets. Typical amide N-H...O=C hydrogen bonds [as C(4) chains] are not present [N...O = 3.438 (2) Å in (I), 3.562 (2) Å in (II) and 3.7854 (16) Å in (III)]; the C=O group is effectively shielded and only participates in weaker interactions/contacts. This series is unusual as the three isomers are isomorphous (having similar unit-cell parameters, packing and alignment), but they differ in their interactions and contacts at the secondary level

3-Fluoro-N-(3-fluoro­benzo­yl)-N-(2-pyrid­yl)benzamide

The title compound, C19H12F2N2O2, a 2:1 product of the reaction of 3-fluoro­benzoyl­chloride and 2-amino­pyridine crystallizes with a disordered 3-fluoro­benzene ring adopting two conformations [ratio of occupancies 0.959 (4):0.041 (4)]. In the crystal structure, there are no classical hydrogen bonds and inter­actions comprise C—H⋯O in the form 2(C—H)⋯O=C [with motif R 2 1(5)]; C—H⋯π(arene) inter­actions are also present

2-Fluoro-N-(2-fluoro­benzo­yl)-N-(2-pyrid­yl)benzamide

The title compound, C19H12F2N2O2, a 2:1 product of the reaction of 2-fluoro­benzoyl chloride and 2-amino­pyridine, crystallizes with a disordered 2-fluoro­benzene ring adopting two conformations [ratio of occupancies = 0.930 (4):0.070 (4)] in one of the two independent mol­ecules (differing slightly in conformation) comprising the asymmetric unit. In the crystal structure, C—H⋯O and C—H⋯π(arene) inter­actions are present

The role of community-based Hubs in reef restoration: Collaborative monitoring at Moore Reef

The Cairns-Port Douglas region is home to multiple coral rehabilitation and stewardship projects supported by scientists, Traditional Owners, and a range of local stakeholders. The Cairns-Port Douglas Reef Hub has been a platform for collaboration across Traditional Owners, tourism operators, not-for-profits and scientists from the Reef Restoration and Adaptation Program (AIMS and CSIRO) to design and deliver a project at Moore Reef that assesses how new techniques for assisted coral recovery can be applied in rubble habitats. The collaborative project evaluates the viability of newly engineered coral seeding devices developed by AIMS, for deploying coral recruits that were spawned in the National Sea Simulator in December 2022 to sites at Moore Reef close to tourist pontoons. This project provides important data to inform future scaling up of restoration activities and provides a model for active involvement of a range of partners. Through this work, the project builds understanding around key ingredients for best-practice, place-based engagement opportunities for Reef communities and the general public

Administrative Burden in Federal Student Loan Repayment, and Socially Stratified Access to Income-Driven Repayment Plans

This study considers socially stratified take-up of income-driven repayment plans among federal student loan borrowers with high-debt payment obligations. Qualitative analyses of borrower complaints from the Consumer Financial Protection Bureau are used to document borrowers’ experiences of administrative burden in the federal loan repayment system. The combined effects of burdens on access to payment relief programs are quantified using both administrative data from a national sample of consumer credit reports and restricted-use survey data from the Beginning Postsecondary Longitudinal Study (BPS). Socioeconomic and racial gaps in take-up of income-driven repayment (IDR) plans are estimated among the subset of borrowers who would face high loan payment-to-income ratios under a standard repayment plan. Regression models indicate that among these borrowers, those living in lower-income census blocks are less likely to be enrolled in IDR

Reviews: Act Naturally

Bethany Easton, Lecturer in Project Management, University of Cumbria, reviews the book 'Act Naturally: The Beatles on Film' by Steve Matteo (Lanham, MD: Rowman and Littlefield, 2023 ISBN: 9781493059010, 350 pp.). With an impressive and ever-expanding number of films on the Beatles, it is only natural that authors are producing texts that examine this particular element of the group’s history. Steve Matteo delves into this area in Act Naturally: The Beatles on Film, in which he explores the Beatles’ various escapades in the film world, from A Hard Day’s Night (dir. Richard Lester, 1964) to Peter Jackson’s (2021) The Beatles: Get Back. Matteo details his aim from the outset: to offer Beatles fans an engaging but informative text exploring the Beatles on film through a mix of images, description and fact. Each chapter details exact dates, locations and events: "April 7th featured shooting the pub cellar sequence where Ringo is confronted by Raja the Bengal tiger, who turns into a pussycat whenever he hears the fourth movement of Beethoven’s Ninth Symphony, commonly known as ‘Ode to Joy’. (138)". Although Matteo self-describes as not being ‘a film scholar’ (vi), his work indicates the contrary, as he presents his meticulously researched findings throughout. This level of detail goes beyond solely exploring the Beatles. There is an enormous amount of historical cinematic context that preceded and surrounded the group’s film work, including the ‘new British film wave: realist films, social problem films, and what came to be known as “kitchen sink” films’ (11). As the author notes, ‘This book is as much a celebration of the films of the Beatles, as it is a championing of the British films of the 1960s in general’ (vi)

Structural systematics and conformational analyses of a 3x3 isomer grid of fluoro-N-(pyridyl)benzamides: physicochemical correlations, polymorphism and isomorphous relationships

An isomer grid of nine fluoro-N-(pyridyl)benzamides (Fxx) (x = para-/meta-/ortho-) has been examined to correlate structural relationships between the experimental crystal structure and ab initio calculations, based on the effect of fluorine (Fx) and pyridine N-atom (x) substitution patterns on molecular conformation. Eight isomers form N—H...N hydrogen bonds, and only one (Fom) aggregates via intermolecular N—H...O=C interactions exclusively. The Fpm and Fom isomers both crystallize as two polymorphs with Fpm_O (N—H...O=C chains, P-syn) and Fpm_N (N— H...N chains, P-anti) both in P21/n (Z0 = 1) differing by their meta-N atom locations (P-syn, P-anti; Npyridine referenced to N—H), whereas the disordered Fom_O is mostly P-syn (Z` = 6) compared with Fom_F (P-anti) (Z` = 1). In the Fxo triad twisted dimers form cyclic R22(8) rings via N—H...N interactions. Computational modelling and conformational preferences of the isomer grid demonstrate that the solid-state conformations generally conform with the most stable calculated conformations except for the Fxm triad, while calculations of the Fox triad predict the intramolecular N— H...F interaction established by spectroscopic and crystallographic data. Comparisons of Fxx with related isomer grids reveal a high degree of similarity in solid-state aggregation and physicochemical properties, while correlation of the melting point behaviour indicates the significance of the substituent position on melting point behaviour rather than the nature of the substituent

Understanding the incidence and timing of rabies cases in domestic animals and wildlife in south-east Tanzania in the presence of widespread domestic dog vaccination campaigns

The “Zero by 30” strategic plan aims to eliminate human deaths from dog-mediated rabies by 2030 and domestic dog vaccination is a vital component of this strategic plan. In areas where domestic dog vaccination has been implemented, it is important to assess the impact of this intervention. Additionally, understanding temporal and seasonal trends in the incidence of animal rabies cases may assist in optimizing such interventions. Data on the incidence of probable rabies cases in domestic and wild animals were collected between January 2011 and December 2018 in thirteen districts of south-east Tanzania where jackals comprise over 40% of reported rabies cases. Vaccination coverage was estimated over this period, as five domestic dog vaccination campaigns took place in all thirteen districts between 2011 and 2016. Negative binomial generalized linear models were used to explore the impact of domestic dog vaccination on the annual incidence of animal rabies cases, whilst generalized additive models were used to investigate the presence of temporal and/or seasonal trends. Increases in domestic dog vaccination coverage were significantly associated with a decreased incidence of rabies cases in both domestic dogs and jackals. A 35% increase in vaccination coverage was associated with a reduction in the incidence of probable dog rabies cases of between 78.0 and 85.5% (95% confidence intervals ranged from 61.2 to 92.2%) and a reduction in the incidence of probable jackal rabies cases of between 75.3 and 91.2% (95% confidence intervals ranged from 53.0 to 96.1%). A statistically significant common seasonality was identified in the monthly incidence of probable rabies cases in both domestic dogs and jackals with the highest incidence from February to August and lowest incidence from September to January. These results align with evidence supporting the use of domestic dog vaccination as part of control strategies aimed at reducing animal rabies cases in both domestic dogs and jackals in this region. The presence of a common seasonal trend requires further investigation but may have implications for the timing of future vaccination campaigns