Relationship Between Changes In Foot Strike Pattern And Indices Of Fatigue In A Maximal 800-Meter Run

During faster, shorter distances, such as an 800-m middle distance, it is unclear whether runners are able to maintain a FF strike pattern. The purpose of this study was to evaluate changes in FSP throughout a maximal 800-m run. Twenty-one subjects (14 female, 7 male; age: 23.86 ± 4.25 yrs) were recruited for this study from the surrounding area and university. Subjects completed a maximal effort 800-m run while FSP and muscle activity of the tibialis anterior (TA) and lateral gastrocnemius (LG) were assessed. The main results showed there was a significant increase in split times throughout the 800-meter run (F [3, 60] = 15.188, p< 0.001). There were significant differences seen between curves and straight intervals for average angular velocity of the foot (F [1, 20] = 21.707, p<0.001) and average change in foot angle (F [1, 20] = 18.445, p<0.001). FSP did not change throughout the 800-m run, with subjects remaining in a more FF strike position; however, there were significant differences in FSP between straight intervals and curve intervals, where subjects employed a more FF strike on the curve intervals compared to straight intervals

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead