2,578 research outputs found

    Building a sustainable approach to mental health work in schools

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    Sustainability is a major challenge to mental health work in schools, and many initiatives started by well-meaning individuals and agencies fade quickly. This paper outlines some key actions that can be taken to ensure that mental health work is sustained, as well as introduced, in schools. These actions include demonstrating that mental health work meets educational goals such as learning and the management of behaviour, using a positive model of mental well-being to which it is easy for those who work in schools to relate, using mentalhealth experts as part of a team, forging alliances with other agencies and working with a whole-school approach. Such approaches are more likely to meet the needs of people with more severe mental problems and provide a more stable platform for specialist interventions than targeted programmes. The paper goes on to suggest some practical steps to sustain work at the school level. These steps include assessing the current position, developing the vision, identifying the gaps, determining readiness and assessing the scene for change, securing consensus, planning the change, establishing criteria, and managing, evaluating and maintaining the change

    Alien Registration- Murray, Katherine (Portland, Cumberland County)

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    https://digitalmaine.com/alien_docs/22005/thumbnail.jp

    Alien Registration- Murray, Katherine (Portland, Cumberland County)

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    https://digitalmaine.com/alien_docs/22005/thumbnail.jp

    Alien Registration- Murray, Katherine (Portland, Cumberland County)

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    https://digitalmaine.com/alien_docs/22005/thumbnail.jp

    Alien Registration- Murray, Katherine (Portland, Cumberland County)

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    https://digitalmaine.com/alien_docs/22005/thumbnail.jp

    Foreword

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    The University ofRichmond Law Review is pleased to present the seventh annual Allen ChairSymposium issue. Through the generous support of the friends and family of George E. Allen, the annual symposium series provides a forum for discussion of legal issues of national and international significance. This issue ofthe Law Review is the literary complement to the symposium presentations

    The phenotype of sporadic CJD in the UK between 1993-2004, and a review of the diagnostic criteria and differential diagnosis

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    BACKGROUND / AIMS Sporadic CJD is a rare but universally fatal neurodegenerative disease of unknown aetiology that occurs worldwide. This study aims to characterise UK sCJD cases between 1993 and 2004 looking for evidence of change over time. Transmission of cattle BSE to humans, with subsequent development of variant CJD, has raised concerns that other novel phenotypes of human prion disease may develop with potentially major public health implications. This study addresses this by reviewing suspect sCJD patients referred before and after the identification of vCJD, by evaluating the phenotype of young onset compared to older onset sCJD and by comparing UK cases with the sCJD databases in France and other predominantly European countries with lower BSE exposure. This study also aims to review the WHO sCJD diagnostic criteria and hence explore the differential diagnosis of sCJD in the UK.METHODS All suspected sCJD cases referred to the NCJDSU between 1993 and 2004 were evaluated by retrospective case note review using the NCJDSU archives. A more detailed analysis of clinical phenotype was performed on patients referred in 1993, 1994, 2003 and 2004, all cases with a negative 14-3-3 result and all patients aged 50 or less at disease onset. MRI, CSF, EEG and pathology results were analysed. UK data were compared with European sCJD data extracted from the EUROCJD database. Suspect sCJD cases that ultimately received an alternative, non CJD diagnosis were reviewed, and the WHO sCJD criteria were evaluated.RESULTS AND CONCLUSIONS There is no evidence to support emergence of a novel, BSE related phenotype of human prion disease. The sCJD demographic data and clinical phenotype are reassuringly similar between 1993/4 and 2003/4, between young and older onset cases and between UK and other European cases. The small number of changes that have been observed can largely be attributed to alterations in data collection and investigation use, plus improved case ascertainment. There is a suggestion that the proportion of PRNP MM cases is decreasing in the UK and France, most likely related to improved identification of atypical presentations. However, continued close observation of PRNP trends is important. The current WHO diagnostic criteria for sCJD are a useful tool, both for research purposes and clinicians in daily practise. Incorporation of CSF 14-3-3 into the Probable sCJD classification has resulted in improved sensitivity of 72% but at the expense of moderate reduction in specificity to 79%. The positive predictive value remains high of 89%. Currently there is insufficient evidence to support inclusion of MRI in the diagnostic criteria.The differential diagnosis of sCJD is wide but Alzheimer's disease is the condition most commonly mistaken for sCJD. However, a significant minority of individuals initially suspected of having CJD never receive a diagnosis, sometimes even after neuropathological studies. Accurate disease surveillance remains a priority, not only to ensure that atypical sCJD presentations are not misdiagnosed, but also to assess putative risk factors for developing sCJD and to identify any novel CJD phenotypes that may emerge in the future

    Dobbs and Democracy

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    In Dobbs v. Jackson Women’s Health Organization, Justice Alito justified the decision to overrule Roe v. Wade and Planned Parenthood of Southeastern Pennsylvania v. Casey with an appeal to democracy. He insisted that it was “time to heed the Constitution and return the issue of abortion to the people’s elected representatives.” This invocation of democracy had undeniable rhetorical power: it allowed the Dobbs majority to lay waste to decades’ worth of precedent, while rebutting charges of judicial imperialism and purporting to restore the people’s voices. This Article interrogates Dobbs’s claim to vindicate principles of democracy, examining both the intellectual pedigree of this claim and its substantive vision of democracy. In grounding its decision in democracy, the Dobbs majority relied on a well-worn but dubious narrative: that Roe, and later Casey, disrupted ongoing democratic deliberation on the abortion issue, wresting this contested question from the people and imposing the Court’s own will. The majority insisted that this critique had always attended Roe. However, in tracing the provenance of the democratic deliberation argument, this Article finds more complicated intellectual origins. In fact, the argument did not surface in Roe’s immediate aftermath, but rather emerged years later. And it did so not organically, but through a series of interconnected legal, movement, and political efforts designed to undermine and ultimately topple Roe and Casey. The product of these efforts, the Dobbs majority’s claim that democracy demanded overruling Roe and Casey, was deployed to overcome the force of stare decisis in Dobbs — and may ultimately reshape the scope and substance of the Court’s stare decisis analysis in future cases. Having identified the intellectual origins of the democratic deliberation argument and its contemporary consequences, this Article examines the contours of the Dobbs majority’s vision of democratic deliberation. We show that although Dobbs trafficked in the rhetoric of democracy, its conception of democracy was both internally inconsistent and extraordinarily limited, even myopic. The opinion misapprehended the processes and institutions that are constitutive of democracy, focusing on state legislatures while overlooking a range of other federal, state, and local constitutional actors. As troublingly, it reflected a distorted understanding of political power and representation — one that makes political power reducible to voting, entirely overlooking metrics like representation in electoral office and in the ecosystem of campaign finance. The opinion was also willfully blind to the antidemocratic implications of its “history and tradition” interpretive method, which binds the recognition of constitutional rights to a past in which very few Americans were meaningful participants in the production of law and legal meaning. The deficits of the Dobbs majority’s conception of democracy appear even more pronounced when considered alongside the Court’s recent and active interventions to distort and disrupt the functioning of the electoral process. Indeed, Dobbs purported to “return” the abortion question to the people and to democratic deliberation at the precise moment when the Court’s own actions have ensured that the extant system is unlikely either to produce genuine deliberation or to yield widely desired outcomes. Ultimately, a close examination of the Dobbs majority’s invocation of democracy suggests that the majority may have employed the values and vernacular of democracy as a means to a different end. As we explain, the majority’s embrace of democracy and democratic deliberation allowed it to shield its actions from claims of judicial activism and overreach. More profoundly, and perhaps paradoxically, the opinion may lay the groundwork for the eventual vindication and protection of particular minority interests — those of the fetus. With this in mind, the Dobbs majority’s settlement of the abortion question is unlikely to be a lasting one. Indeed, aspects of the opinion suggest that this settlement is merely a way station en route to a more permanent resolution — the recognition of fetal personhood and the total abolition of legal abortion in the United States

    Janus Dendritic Ligands for Nanoparticle Assemblies

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    This project was conducted in the laboratory of Professor Christopher B. Murray at the University of Pennsylvania. The project described herein includes the synthesis of a Janus dendrimer as well as complimentary dendrimers of hydrophobic and hydrophilic nature to study the self-assembly and organizational properties of these molecules on gold surfaces. A complete synthesis and characterization of these molecules is described, as well as grafting the molecules onto both gold nanoparticle and thin film surfaces. How the different dendritic molecules guide self-assembly of the nanoparticles and how the Janus molecule assembles itself on a gold surface was studied. To characterize these systems, TEM and solid state UV-vis were employed, and general trends are described herein
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