“The Skeptics Agenda” and What Science Now Says about Global Warming

In the Margaret Chase Smith essay, Robert Kates discusses global climate change. He notes that there is no longer any doubt that global warming is occurring, caused most likely by increased greenhouse gasses. Costs of preventing warming are mixed, and appropriate timing of such efforts is unknown, but there is no doubt that societal attention is needed for adaptation

Interview with Robert Kates, Pathfinder in Sustainability Science

In this interview, Robert Kates discusses the challenges of sustainability science in moving from what scientists know to actions that can provide solutions to pressing environmental and development problems. Kates notes that sustainability science has the dual mission of addressing core scientific and intellectual questions, while at the same time addressing development in particular places. He suggests that one of the key questions is how to address long-term trends and transition to a “better synthesis between environment and society.

Velo-Cardio-Facial Syndrome

Purpose of review: Velo-cardio-facial syndrome has emerged from obscurity to become one of the most researched disorders this past decade. It is one of the most common genetic syndromes in humans, the most common contiguous gene syndrome in humans, the most common syndrome of cleft palate, and the most common syndrome of conotruncal heart malformations. Velo-cardio-facial syndrome has an expansive phenotype, a factor reflected in the wide range of studies that cover both clinical features and molecular genetics. In this review, we cover multiple areas of research during the past year, including psychiatric disorders, neuroimaging, and the delineation of clinical features. Recent findings: The identification of candidate genes for heart anomalies, mental illness, and other clinical phenotypes has been reported in the past year with a focus on TBX1 for cardiac and craniofacial phenotypes and COMT and PRODH for psychiatric disorders. The expansive phenotype of velo-cardio-facial syndrome continues to grow with new behavioral and structural anomalies reported. Treatment issues are beginning to draw attention, although most authors continue to focus on diagnostic issues. Summary: Its high population prevalence, estimated to be as common as 1:2000 has sparked a large amount of research, as has the model the syndrome serves for identifying the causes of mental illness and learning disabilities, but it is obvious that more information is needed. Intensive scrutiny of velo-cardio-facial syndrome will undoubtedly continue for many years to come with the hope that researchers will turn more of their attention to treatment and treatment outcomes

Knowing Better and Losing Even More: The Use of Knowledge in Hazards Management

Although loss of life from natural hazards has been declining, the property losses from those causes have been increasing. At the same time the volume of research on natural hazards and the books reviewing findings on the subject have also increased. Several major changes have occurred in the topics addressed. Emphasis has shifted from hazards to disasters. There has been increasing attention to vulnerability. Views of causation have changed. Four possible explanations are examined for the situation in which more is lost while more is known: (1) knowledge continues to be flawed by areas of ignorance; (2) knowledge is available but not used effectively; (3) knowledge is used effectively but takes a long time to have effect; and (4) knowledge is used effectively in some respects but is overwhelmed by increases in vulnerability and in population, wealth, and poverty

Cognitive and Psychiatric Predictors to Psychosis in Velocardiofacial Syndrome: A 3-Year Follow-Up Study

Objective: To predict prodromal psychosis in adolescents with velocardiofacial syndrome (VCFS). Method: 70 youth with VCFS, 27 siblings of youth with VCFS and 25 community controls were followed from childhood (Mean age = 11.8 years) into mid-adolescence (mean age 15.0 years). Psychological tests measuring intelligence, academic achievement, learning/memory, attention and executive functioning as well as measures of parent and clinician ratings of child psychiatric functioning were completed at both time point. Results: Major depressive disorder, oppositional defiant disorder, and generalized anxiety disorder diagnoses increased in the VCFS sample. With very low false positive rates, the best predictor of adolescent prodromal psychotic symptoms was parent ratings of childhood odd/eccentric symptoms and child performance on a measure of executive functioning, the Wisconsin Card Sorting Test. Conclusions: Similar to the non-VCFS prodromal psychosis literature, a combination of cognitive and psychiatric variables appears to predict psychosis in adolescence. A child with VCFS who screens positive is noteworthy and demands clinical attention