1,249 research outputs found

    学術情報マネージメント、ERMS、次世代OPAC

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    多くの大学と同様、九州大学でも雑誌の電子ジャーナル化が進み、冊子体に取って代わってきている。また、図書館の利用統計は、入館、貸出、レファレンス、ILLといった来館サービスと同様に、またはそれ以上に、電子ジャーナル、所蔵検索、文献検索、リンクリゾルバといったeリソースが利用されていることを示しており、ウェブ上での学習・教育・研究支援は重要性を益している。 この発表では、本学で導入した「きゅうとLinQ」(リンクリゾルバ)、「RefWorks」(文献管理)、「どこでもきゅうと」(自宅・出張先からのeリソースアクセス)の事例、および図書館ウェブサイトのリニューアルを紹介する。また、こうした利用環境整備や図書館員による適切なインストラクションが、ユーザーとの繋がりや新たなサービスへのニーズを生み、更なる環境整備の土台となることを説明する。最後に、多様化するeリソースの契約・アクセス・利用を管理するためのERM(eリソース管理)システムの実験について、また図書館が提供する「検索」を整理し、探しやすくするための次世代OPACの検討について、紹介する。平成20年度国立大学図書館協会地区協会助成事業ワークショップ「大学における研究・教育活動と電子リソース利用の現在」発表資料 平成21年1月29日 広島大学中央図書館ライブラリーホー

    Recognition of 2′-hydroxyl groups by Escherichia coli ribonuclease HI

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    AbstractIn order to investigate the hydrogen-bonding interactions between Escherichia coli ribonuclease HI and the 2′-hydroxyl functions of the substrate, oligonucleotide duplexes containing 2′-amino-2′-deoxyuridine or 2′-fluoro-2′-deoxyuridine at a specific site were used, and their affinities for the enzyme were determined by kinetic analyses. The results indicate that the hydroxyl groups of the nucleoside 3′-adjacent to the cleaved phosphodiester linkage and the second nucleoside 5′ to the cleaved phosphodiester act as both a proton donor and an acceptor and as a proton acceptor, respectively, in the enzyme-substrate complex. A molecular model was constructed using the interactions derived from the results

    Effects of Protective Measures against COVID-19 on Auditory Communication for People with Hearing Loss

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    WHO has recommended various measures to combat the COVID-19 pandemic, including mask-wearing and physical distancing. However, these changes impair communication for individuals with hearing loss. We investigated the changes in auditory communication associated with COVID-19 measures in 269 patients (male: 45.7%, female: 54.3%, median age: 54 y.o.). Most patients with hearing loss had difficulty engaging in auditory communication with people wearing masks, especially in noisy surroundings or with physical distanc-ing. These difficulties were noticeable in patients with severe hearing loss. Developing communication support strategies for people with hearing loss is an urgent need while COVID-19 measures are in place

    Cochlear Implantation in the Poorer-Hearing Ear Is a Reasonable Choice

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    Choosing the optimal side for cochlear implantation (CI) remains a major challenge because of the lack of evidence. We investigated the choice of the surgery side for CI (i.e., the better- or poorer-hearing ear) in patients with asymmetric hearing. Audiological records of 74 adults with a unilateral hearing aid who had undergone surgery at Okayama University Hospital were reviewed. The definition of ‘better-hearing ear’ was the aided ear, and the unaided ear was considered the poorer-hearing ear. We performed a multiple regression analysis to identify potential predictors of speech recognition performance after unilateral CI in the patients. Fifty-two patients underwent CI in the poorer-hearing ear. The post-Ci bimodal hearing rate was far higher in the poorer-ear group (77.8% vs. 22.2%). A multivariate analysis revealed that prelingual hearing loss and the patient’s age at CI significantly affected the speech recognition outcome (beta coefficients: 24.6 and −0.33, 95% confidence intervals [11.75-37.45] and [−0.58 to −0.09], respectively), but the CI surgery side did not (−6.76, [−14.92-1.39]). Unilateral CI in the poorer-hearing ear may therefore be a reasonable choice for adult patients with postlingual severe hearing loss, providing a greater opportunity for postoperative bimodal hearing

    Measuring the Broad-band X-Ray Spectrum from 400 eV to 40 keV in the Southwest Part of the Supernova Remnant RX J1713.7-3946

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    We report on results from Suzaku broadband X-ray observations of the southwest part of the Galactic supernova remnant (SNR) RX J1713.7-3946 with an energy coverage of 0.4-40 keV. The X-ray spectrum, presumably of synchrotron origin, is known to be completely lineless, making this SNR ideally suited for a detailed study of the X-ray spectral shape formed through efficient particle acceleration at high speed shocks. With a sensitive hard X-ray measurement from the HXD PIN on board Suzaku, we determine the hard X-ray spectrum in the 12--40 keV range to be described by a power law with photon index Gamma = 3.2+/- 0.2, significantly steeper than the soft X-ray index of Gamma = 2.4+/- 0.05 measured previously with ASCA and other missions. We find that a simple power law fails to describe the full spectral range of 0.4-40 keV and instead a power-law with an exponential cutoff with hard index Gamma = 1.50+/- 0.09 and high-energy cutoff epsilon_c = 1.2+/- 0.3 keV formally provides an excellent fit over the full bandpass. If we use the so-called SRCUT model, as an alternative model, it gives the best-fit rolloff energy of epsilon_{roll} = 0.95+/- 0.04 keV. Together with the TeV gamma-ray spectrum ranging from 0.3 to 100 TeV obtained recently by HESS observations, our Suzaku observations of RX J1713.7-3946 provide stringent constraints on the highest energy particles accelerated in a supernova shock.Comment: 11 pages, 11 figures, accepted for publication in Publications of the Astronomical Society of Japan (PASJ
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