757 research outputs found

    Emergence of multi-drug resistant strains among bacterial isolates in burn wound swabs in a tertiary care centre, Nanded, Maharashtra, India

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    Background: Infection is a major cause of morbidity and mortality among burn patients. The worldwide emergence of antimicrobial resistance among a wide variety of burn wound pathogens, particularly nosocomial isolates, limits the available therapeutic options for effective treatment of burn wound infections. The study was conducted in the department of Microbiology, Dr. S.C.G.M.C, Nanded, Maharashtra, India to determine aerobic bacterial isolates from burn wound swabs and describe their antibiogram.Methods: Two wound swabs were taken from 570 patients, cultured aerobically. The isolates were identified by standard microbiological methods and antibiotic sensitivity pattern was determined.Results: Among 570 patients, 434 (76.14%) were female and 136 (23.85%) were male. Out of the total swabs collected, 548 (96.14%) were culture positive and 36 (6.56%) were having 2 isolates. Pseudomonas aeruginosa (34.93%) was the commonest isolate followed by Staphylococcus aureus (22.77%), Klebsiella pneumoniae (13.87%), Escherichia coli (13.01%) and Coagulase negative staphylococcus (11.31%). Incidence of MRSA was 59.39% and ESBL producers were 61.46 %. Gram positive isolates were 100% sensitive to Vancomycin, Linezolid and Gram negative organisms to Imipenem.Conclusions: Routine periodic sampling of burn wounds would facilitate the selection of appropriate empirical therapy and reduce the incidence of multidrug resistant infections among burn patients

    High-Performance Silicon-Based Multiple Wavelength Source

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    We demonstrate a stable CMOS-compatible on-chip multiple-wavelength source by filtering and modulating individual lines from a frequency comb generated by a microring resonator optical parametric oscillator.. We show comb operation in a low-noise state that is stable and usable for many hours. Bit-error rate measurements demonstrate negligible power penalty from six independent frequencies when compared to a tunable diode laser baseline. Open eye diagrams confirm the fidelity of the 10 Gb/s data transmitted at the comb frequencies and the suitability of this device for use as a fully integrated silicon-based WDM source.Comment: 3 pages, 3 figure

    Pili multigemini of the eye: unusual and rare presentation

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    Pili Multigemini (PM) is an uncommon, pilar dysplasia characterized by clusters of hair shafts emerging from a single follicle. We present a rare and unique case of PM involving the eye. A 43 year old Caucasian male, presented with a prolonged history of a recurrent lesion at the right upper eyelid, present for two years. Clinical examination revealed a subcutaneous cyst with a prominent follicular pore with a differential diagnosis of epidermoid cyst, nevus and pili bifurcati. Excisional biopsy was performed and microscopy showed a benign malformed hair follicle containing multiple different hair shafts enclosed in a common outer root sheath; consistent with the diagnosis of Pilli Multigemini. Pili Multigemini was first described by Flemming in 1883 and is frequently found in the beard of adults and scalp of children. To our knowledge, this is the first case of Pilli Multigemini involving the eye. its noteworthy to consider during diagnostic workup; as well as to exclude other follicular and inflammatory abnormalities involving the eye

    HUBUNGAN TINGKAT PENGETAHUAN IBU HAMIL TENTANG NUTRISI DENGAN PERILAKU KONSUMSI MAKANAN SELAMA KEHAMILAN DI PUSKESMAS BANYU URIP KIDUL SURABAYA

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    Kurangnya pengetahuan ibu terhadap manfaat nutrisi selama kehamil dapat menyebabkan ibu kekurangan nutrisi selama kehamilannya, masih banyak perilaku ibu hamil yang salah dalam memilih nutrisi di antaranaya nasi, ikan, sayur, buah, dan susu. Tujuan penelitian ini adalah untuk mengetahui hubungan antara pengetahuan dan perilaku ibu hamil tentang nutrisi selama kehamilan di Puskesmas Banyu Urip Kidul Surabaya. Desain penelitian ini adalah cross sectional. Populasi penelitian ini yaitu seluruh ibu hamil di Puskesmas Banyu Urip Kidul Surabaya sebanyak 35 ibu hamil. Pengambilan sampel menggunakan probability sampling dengan teknik yang digunakan simple random sampling yaitu sejumlah 33 responden. Variabel independen adalah Tingkat pengetahuan ibu hamil, variable dependen adalah Perilaku konsumsi makanan selama kehamilan. Intrumen menggunakan lembar kuesioner. Data analisis menggunakan uji statistic Rank Spearman dengan α = 0,05 Hasil penelitian menunjukan bahwa setelah dilakukan uji statistik Rank Spearmen dengan tingkat kemaknaan α = 0.05 didapatkan nilai ρ = 0,000 dan α = 0.05, bearti ρ < α, maka H0 ditolak yang artinya ada hubungan tingkat pengetahuan ibu hamil tentang nutrisi dengan perilaku konsumsi makanan selama kehamilan di Puskesmas Banyu Urip Kidul Surabaya. Semakin baik pengetahuan ibu hamil tentang nutrisi maka semakin baik juga perilaku konsumsi makanan yang sesuai selama kehamilan. Oleh Karena itu, sebagai saran adalah ibu hamil harus mendambah informasi tentang nutrisi selama kehamilan

    PENERAPAN TERAPI SLEEP HYGENE PADA ANAK USIA SEKOLAH DENGAN MASALAH KEPERAWATAN GANGGUAN POLA TIDUR AKIBAT PENGGUNAAN GADGET DI RW 14 RT 03 KELURAHAN SIDOTOPO WETAN KECAMATAN KENJERAN KOTA SURABAYA

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    Tidur merupakan salah satu kebutuhan dasar bagi seorang anak. Bermain gadget adalah salah satu penyebab gangguan pola tidur pada anak yang dapat mempengaruhi perilaku dan emosi anak, mudah lelah selain itu dapat menyebabkan kesulitan anak dalam jatuh tidur serta sering terbangun di malam hari. Penelitian ini bertujuan untuk mengetahui penerapan terapi Sleep Hygiene pada anak usia sekolah terhadap penggunaan gadget dengan masalah keperawatan gangguan pola tidur. Desain penelitian menggunakan studi kasus yang dilakukan pada seorang anak dengan masalah keperawatan gangguan pola tidur. Penelitian dilakukan di RW14 RT 03 Kelurahan Sidotopo Wetan Kecamatan Kenjeran Kota Surabaya. Metode pengumpulan data dengan melakukan wawancara, observasi, dan pemeriksaan fisik, kemudian untuk penerapannya dilakukan selama 3 hari sebelum tidur dengan melakukan komponen terapi sleep hygiene dari jadwal tidur, persiapan tidur dan lingkungan tidur lalu dilakukan observasi setelah bangun tidur dan dievaluasi. Hasil yang didapatkan setelah penerapan asuhan keperawatan dengan menggunakan sleep hygiene pada anak yaitu kualitas dan kuantitas tidur anak lebih baik dimana hari pertama jam tidur anak dimulai dari pukul 22.30 hingga 06.00 sedangkan hari ketiga dimulai pukul 21.00 hingga 05.00 Sleep Hygiene dapat membantu gangguan pola tidur pada anak. Disarankan pada keluarga atau masyarakat untuk menerapkan terapi Sleep Hygiene ini sebagai upaya penanganan pada anak yang mengalami masalah gangguan pola tidur

    Biophysical investigations on the active site of brain hexokinase

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    Replacement of Mg (II), the natural activator of brain hexokinase (EC 2.7.1.1) by paramagnetic Mn (II) without affecting the physiological properties of the enzyme, has rendered brain hexokinase accessible to investigations by magnetic resonance methods. Based on such studies, a site on the enzyme, where Mn (II) binds directly with high affinity has been identified and characterized in detail. Use of β,γ-bidentate Cr (III) ATP as an exchange-inert analogue for Mn (II) ATP has shown that Mn (II) binding directly to the enzyme has no catalytic role but another Mn (II) ion binding simultaneously and independently to the enzyme through the nucleotide bridge participates in enzyme function. However, using this direct binding Mn (II) ion and a covalently bound spin label as paramagnetic probes a beginning has been made in mapping the ligand binding sites of the enzyme. Ultra-violet difference spectroscopy has revealed the presence of at least two glucose 6-phosphate locations on the enzyme one of which presumably is the high affinity regulatory site modulated by substrate glucose. Elution behaviour of the enzyme on a phosphocellulose column suggests that glucose induces a specific phosphate site on the enzyme to which the phosphate bearing regulatory ligands of the enzyme may bind
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