46 research outputs found

    Aligning Corporate Strategies with the Sustainable Development Goals

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    The preceding three decades have been characterised by several social, technological, and environmental changes, which have customized the operational environment of corporations. One of those changes is the emergence of green sustainability (Gray, 1994; Abbas, 2019), which has an interlacing effect on creating customer value and sustaining companies’ environmental, social, and financial performance. The responses to these important issues are gaining relevance, increasing the impetus for companies to develop new business models consistent with this paradigm and share this information with external stakeholders, including the public. Such an approach will help create a holistic, integrated view of implementing sustainable development practices and foster a new culture consistent with a large-scale transition to a green sustainable future

    Corporate strategies for sustainable development and adoption of new technologies

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    Technological advancements might have positive or negative impacts on sustainability. It’s essential to understand the adoption of these technologies to achieve better sustainability. The United Nations 2030 Agenda and the associated SDGs have been promoted as tools suitable to alleviate poverty, protect Planet Earth, and contribute to worldwide prosperity (UN, 2015; Tsalis, 2020). But governments alone cannot achieve sustainable development; they must be supported by the private sector, which plays a colossal role in advancing and achieving the SDGs. Specifically, the private sector can integrate the ‘green’ principles into their corporate strategies. This integration depends on, and requires, an effective approach to green development and the knowledge generation of SDGs as embedded in the companies’ functions, values, and day-to-day operations. The papers in this special issue investigate the role of corporate strategies for sustainable green development and knowledge generation in the implementation of the SDGs or principles by Asian and Eastern European companies from Malaysia, Vietnam, Indonesia, Emirates, Zimbabwe and Russia. Hence, there is a need to expand the research in further studies to gauge the contribution of corporate strategies towards the achievement of the SDGs in a wider group of countries. These further studies could also focus on a comparative cross-country analysis to provide insights into how institutional differences among countries influence the implementation and achievement of the SDGs. In addition, there is also a need to understand the role of other corporate strategies, including integrated reporting and long-term value, in the achievement of the SDGs. It is a matter of great importance for companies to explain how businesses create value for their key stakeholders in the long term by implementing the SDGs. The insights drawn from this special issue contribute to the existing literature and provide valuable practical information for practitioners, policymakers, and developers. Practitioners can rely on the insights provided in this special issue to make informed decisions that consider both the short-term and long-term impacts of technology solutions and their adoption in organizations. They need to consider the opportunities and challenges associated with technology adoption and develop plans to mitigate the negative impacts and maximize the positive effects of technology adoption. Additionally, policymakers can use the findings of the eight papers to establish policies and regulations that encourage the adoption of sustainable technologies that serve society while minimizing the negative impacts on the environment, economy, and the general public. Further, developers can consider the barriers identified in the analysis to develop more effective solutions. They can also incorporate sustainable practices into the development process to ensure their technologies align with sustainable development principles

    CyberEntRel: Joint Extraction of Cyber Entities and Relations using Deep Learning

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    The cyber threat intelligence (CTI) knowledge graph is beneficial for making robust defense strategies for security professionals. These are built from cyber threat intelligence data based on relation triples where each relation triple contains two entities associated with one relation. The main problem is that the CTI data is increasing more rapidly than expected and existing techniques are becoming ineffective for extracting the CTI information. This work mainly focuses on the extraction of cyber relation triples in an effective way using the joint extraction technique, which resolves the issues in the classical pipeline technique. Firstly, the ‘BIEOS’ tagging scheme was applied to CTI data using the joint tagging technique and then the relation triples were jointly extracted. This study utilized the attention-based RoBERTa-BiGRU-CRF model for sequential tagging. Finally, the relation triples were extracted using the relation-matching technique after matching the best suitable relation for the two predicted entities. The experimental results showed that this technique outperformed the state-of-the-art models in knowledge triple extraction on CTI data. Furthermore, a 7% increase in the F1 score also proved the effectiveness of this technique for the information extraction task on CTI data

    Multiwall carbon nanotube reinforced HA/HDPE biocomposite for bone reconstruction

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    The healing of bone fractures naturally occurs without surgical intervention. Some damage and fractures in bone tissue are complex and leave remnant deformation, and this requires the use of bone replacement material. Hydroxyapatite (HA) is the main element of the bone mineral form and consider as a bioactive material which supports bone growth. Nevertheless, the HA has poor mechanical properties, such as low tensile strength. Thus the applications in bone replacement have been limited, especially in high load-bearing applications. A Carbone nanotube has newly obtained considerable concern because of their mechanical properties, potentially enhancing the bone implant's clinical efficiency. This study attempted to explain the effect of adding Multi-walled carbon nanotubes MWCNT Nanoparticles to the HDPE/HA bio-composites. Two groups of the composites samples were produced 20HA/80 HDPE and 40 HA/ 60 HDPE with adding (0.6, 1, 1.4, 2) % weights of (MWCNT) to each group. The composites were fabricated using a hot pressing technique with various pressing pressures (29, 57, 86, and 114 Mpa) at a compounding temperature of 150 C° and a holding time of 15 minutes. To evaluate samples' characteristics and performance, X-ray powder diffraction (XRD), surface topography by Field Emission Scanning Electron Microscopy (FE-SEM), tensile strength and, microhardness test were investigated. The results showed that the hybrid bio-composites demonstrated excellent structural integrity, homogeneous with the fibrous structure, and improved mechanical properties. When increasing in MWNT additions and increasing hot-press pressure, enhancing the composites' fracture strength and microhardness is beneficial. The excellent properties of hybrids bio-composite (HA/HDPE/MWCNT) samples for homogeneous fibrous structure and high mechanical properties could be applied in bone tissue engineering for bone reconstruction

    Prevalence of behavioural and psychological problems in working children

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    OBJECTIVE: To determine the prevalence and screen the nature and types of behavioural and psychological problems among working children in Karachi. METHODS: A cross sectional study was conducted in three urban squatter settlements of Karachi from May to June 2006, targeting working children aged 11-16 years. Behavioural Problems of these children were estimated by using the self reported Urdu version of the Strengths and Difficulty Questionnaire. The results were cross-tabulated using SPSS 13.0 with the identified risk-factors. RESULTS: Out of a total of 225 respondents, 94.2% (n = 212) males and 5.8% (n = 13) females, the prevalence of Behavioural Problems among working children was found to be 9.8%. Peer problems were most prevalent (16.9%) seconded by Conduct problems (16.7%). Adverse family environment and work environment were closely associated with Behavioural Problems in these children. CONCLUSION: Our study reinforces the need for measures to improve the environment of the children and prevent the psychological and behavioural problems associated with working children. Gradual, long-term policies are required to decrease the need for working children, though sudden abolishment would cause more detrimental effects

    Thyrocyte-specific G q /G 11 deficiency impairs thyroid function and prevents goiter development

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    The function of the adult thyroid is regulated by thyroid-stimulating hormone (TSH), which acts through a G protein-coupled receptor. Overactivation of the TSH receptor results in hyperthyroidism and goiter. The G s -mediated stimulation of adenylyl cyclase-dependent cAMP formation has been regarded as the principal intracellular signaling mechanism mediating the action of TSH. Here we show that the G q /G 11 -mediated signaling pathway plays an unexpected and essential role in the regulation of thyroid function. Mice lacking the α subunits of G q and G 11 specifically in thyroid epithelial cells showed severely reduced iodine organification and thyroid hormone secretion in response to TSH, and many developed hypothyroidism within months after birth. In addition, thyrocyte-specific Gα q /Gα 11 -deficient mice lacked the normal proliferative thyroid response to TSH or goitrogenic diet, indicating an essential role of this pathway in the adaptive growth of the thyroid gland. Our data suggest that G q /G 11 and their downstream effectors are promising targets to interfere with increased thyroid function and growth

    Psychological impact of COVID-19 restrictions among individuals at risk of exercise addiction and their socio-demographic correlates: a Saudi Arabian survey study

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    Exercise addiction (EA) has been described as a condition of psychological dysfunction characterized by excessive and obsessive exercise patterns, show withdrawal symptoms when unable to exercise, and experience numerous conflicts and other negative consequences in their social and professional lives, due to the extremely high volumes of exercise. The main objective of the present study was to assess the risk of exercise addiction among a Saudi Arabian sample of regular exercisers and to investigate possible associations between their inability to exercise during the COVID-19 pandemic lockdown (due to the closure of public gyms, swimming pools, and health clubs) and depression, anxiety, and loneliness. A total of 388 regular-exercising Saudis participated in an online cross-sectional survey over three months (December to February 2021). The study sample comprised 89.9% (males) and 10.1% (females), with a mean age of 28.59 years (SD ± 6.69). A 36-item online self-report survey was used for data collection. The prevalence of being at risk of exercise addiction among participants of the present study was 13.1%. Positive significant associations were noted between risk of exercise addiction and depression (r = .41; p < .01), risk of exercise addiction and anxiety (r = .20; p < .01), and risk of exercise addiction and loneliness (r = .17; p < .01). The findings of the present study suggest that those individuals at risk of exercise addiction might also be at an elevated risk of developing negative psychological impact owing to the disruption of the amount of exercise engaged in due to COVID-19 pandemic-related restrictions and therefore these high-risk individuals should receive appropriate psychological support to help them overcome the negative impact of the ongoing pandemic

    Loss of microRNA-7a2 induces hypogonadotropic hypogonadism and infertility

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    MicroRNAs (miRNAs) are negative modulators of gene expression that fine-tune numerous biological processes. miRNA loss-of-function rarely results in highly penetrant phenotypes, but rather, influences cellular responses to physiologic and pathophysiologic stresses. Here, we have reported that a single member of the evolutionarily conserved miR-7 family, miR7a2, is essential for normal pituitary development and hypothalamic-pituitary-gonadal (HPG) function in adulthood. Genetic deletion of mir-7a2 causes infertility, with low levels of gonadotropic and sex steroid hormones, small testes or ovaries, impaired spermatogenesis, and lack of ovulation in male and female mice, respectively. We found that miR-7a2 is highly expressed in the pituitary, where it suppresses golgi glycoprotein 1 (GLG1) expression and downstream bone morphogenetic protein 4 (BMP4) signaling and also reduces expression of the prostaglandin F2a receptor negative regulator (PTGFRN), an inhibitor of prostaglandin signaling and follicle-stimulating hormone (FSH) and luteinizing hormone (LH) secretion. Our results reveal that miR-7a2 critically regulates sexual maturation and reproductive function by interconnecting miR-7 genomic circuits that regulate FSH and LH synthesis and secretion through their effects on pituitary prostaglandin and BMP4 signaling

    The association of dietary behaviors and practices with overweight and obesity parameters among Saudi university students

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    Western dietary habits, coupled with a sedentary lifestyle, are potential contributors to the prevalence and rapid increase in the incidence of obesity in Saudi Arabia. This study aimed to investigate the association between students’ weight status and their eating behaviors and practices. Another aim was to assess students’ awareness of the health risks associated with obesity. Methods A cross-sectional survey was conducted among a sample of 416 (53% male and 47% female) undergraduate students, aged 18–26 years old, between January 6 and April 6, 2019, from colleges of Health Sciences at Jazan University in the Kingdom of Saudi Arabia (K.S.A). Students completed a self-administered questionnaire and recorded their measured anthropometric parameters. Results The prevalence of overweight (20.4%) and obesity (14.9%) were relatively high among the participants. There were statistically significant associations between Body Mass Index (BMI) and the different settings of food consumption (i.e., dining on a table (or) in the Islamic way: squatting on the ground) (p<0.001)). BMI was also associated with students’ dietary habits regarding consuming food, snacks, and drinking carbonated beverages while watching television (p<0.001), as well as consuming the same pattern of food/drink while watching television, playing video games on mobile phones or computers (p<0.001). Nearly most of the students were oblivious to the fact that metabolic syndrome, reproductive disorders, respiratory disorders along with liver and gallbladder diseases are some of the health risks associated with obesity. Conclusion The prevalence of obesity and overweight were reasonably high in our study sample and were affected by several factors related to students’ eating behaviors and practices. This warrants the need for rigorous and frequent health education interventions on healthy eating behaviors, dietary practices, with an emphasis on the importance of adopting an active, healthy lifestyle
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