Hydrocephaly: Medical Treatment

Hydrocephaly is a prevalent condition in all age groups. At present, the most frequent strategies used to treat hydrocephaly are surgical shunting procedures, which are still associated with multiple complications. The main goal of the medical therapy for the lowering of high ventricular pressure is to avoid shunting or to reduce and decrease intracranial pressure (ICP) until shunt surgery. Medications affect cerebrospinal fluid dynamics by decreasing secretion or increasing reabsorption. Medical treatment for manipulation of water balance or cerebrospinal fluid (CSF) production reduces mortality in both infants and adults with neurological disorders. Medical treatment has an important role in the management of hydrocephaly especially in patients not suitable for shunt and in patients whom the shunt alone is not able to control the hydrocephaly. The treatment is used to delay surgical intervention but is not effective in the long treatment of chronic hydrocephaly

Psoriasis Symptom Inventory (PSI) as a patient-reported outcome in mild psoriasis: Real life data from a large psoriatic arthritis registry

Objective: Our aim is to test the validity of the Psoriasis Symptom Inventory (PSI), a patient-reported outcome, to assess the psoriasis severity within the scope of rheumatology. Methods: Within the PsA international database (PSART-ID), 571 patients had PSI, while 322 of these also showed body surface area (BSA). Correlations between PSI, BSA, and other patient- and physician-reported outcomes were investigated. Results: There was a good correlation between PSI and BSA (r=0.546, p<0.001), which was even higher for mild psoriasis (BSA<3 (n=164): T-0.608, p<0.001). PSI significantly correlated with fatigue, pain, and patient and physician global parameters (p<0.001). Conclusion: PSI has a good correlation with other patient- and physician-reported outcomes, and our findings support its use in rheumatology practice

A SUCCESSFUL KIDNEY TRANSPLANTATION WITH PROPHYLACTIC ECULIZUMAB TREATMENT IN A PATIENT WITH ATYPICAL HEMOLYTIC UREMIC SYNDROME

WOS: 000367726702468

A stimulatory role of ozone exposure on human natural killer cells

Ozone is claimed to have beneficial effects. While studies revealed the safe therapeutic use of ozone, there are conflicting results for the link between immune system and ozone encounter. Natural killer (NK) cells are important sentinels of immunity with their cytotoxic activity and immune-regulatory potentials. This study aimed to investigate the effects of direct ozone encountering on human immune system, at cellular level. Survival, proliferative capacity and subset content of peripheral blood mononuclear cells (PBMC) were analysed. PBMC of healthy donors (n = 5, mean age: 27 +/- 6 years) were exposed to 1, 5, 10 and 50 mu g/mL doses of medical ozone, directly injected into culture wells, once, initially. 1 and 5 mu g/mL doses didn't show toxic effects while 10 and 50 mu g/mL doses were toxic. PBMC were cultured for 5 days following 1 and 5 mu g/mL ozone encountering. 1 mu g/mL dose increased numbers of CD3(-)CD16(+)/56(+) NK cells among PBMC. Following stimulation with ozone, no difference was observed in basal and phytohemaglutinin-stimulated proliferative capacity. 1 and 5 mu g/mL doses of ozone were found to increase NK cytotoxicity. These data indicates influential effects of transient ozone exposure on NK cells, which in turn may have a role in control of immune responses

Importación de Lactdew de Yakutl Japón a México

El presente trabajo pretende resaltar los aspectos estratégicos que se tienen para la importación de Lactdew de Yakutl Japón a México. Se estima que debido al crecimiento de la empresa en México se encuentra en expansión y por tal motivo nos mueve a realizar el análisis del proyecto para poder introducir la linea Lactdew

An Evaluation of Exogen Islet Amyloid Polypeptide Injection Efficacy on Interleukin-1Beta and Glycemia in Nondiabetics, Streptozotocin-Induced Diabetics and Rats with Islet Transplantation

Objectives: This study aims to investigate the effect of exogen amylin injection on interleukin-1beta (IL-1 beta) and glycemia levels in healthy, diabetic, with transplantation and with amylin injection rats