Correction to: Cluster identification, selection, and description in Cluster randomized crossover trials: the PREP-IT trials

An amendment to this paper has been published and can be accessed via the original article

Comparison of Propranolol versus Amitriptyline as monotherapy for migraine prophylaxis

Introduction: Several drugs like Beta Blockers, SSRIs etc., are used for migraine prophylaxis. Objectives: The purpose of the present study was to compare the efficacy of propranolol and amitriptyline as monotherapy for the prophylaxis of migraine. Materials and Methods: This was a comparative, double-blinded, Prospective, randomized controlled study conducted at Department of General Medicine at Surabhi Institute of Medical Sciences. A total of 140 patients were enrolled in the study, diagnosed cases of migraine were randomly allocated using random number table to either Group 1 (Period 1: To receive tablet Propranolol 4–16 weeks and Period 2: Amitriptyline 20–32 weeks) or Group 2 (Period 1: To receive tablet Amitriptyline 4–16 weeks and Period 2: Propranolol 20–32 weeks). During the first 4 weeks, the run-in period, the patients do not receive prophylactic treatment and have to record in a headache diary the number of migraine attacks, the duration of attacks in hours and the severity.  Similarly during 16 to 20 weeks patient didn’t receive any prophylactic treatment to wear of the drug effects

Correlation between Glycosylated Haemoglobin and serum lipid profile in patients with type 2 diabetes

Introduction: Dyslipidaemia is one of the major risk factor for cardiovascular disease in Type 2 Diabetes mellitus, characterized by elevated Total cholesterol (TC), Triglycerides (TG), Low density lipoprotein (LDL) and decreased High density lipoprotein (HDL). Haemoglobin A1c (HbA1c) is widely used as an index of mean glycaemia, a measure of risk for the development of diabetes complications and a measure of the quality of diabetes care. The aim of this study was to determine the impact of glycaemic control on lipid profile and to know utility of HbA1c as an indirect indicator of dyslipidaemia. Objectives:  To assess the relationship between glycemic control (HbA1c) and serum lipid profile as well as to evaluate the importance of HbA1c as an indicator of dyslipidemia in patients with T2DM. Materials and Methods: The present study is a prospective, observational study which is conducted in the Department of General Medicine at Surabhi Institute of Medical Sciences over a period of 6 months.  A total of 65 T2DM patients with dyslipidemia who had visited the hospital. Inclusion criteria: Adults aged above 30 years and having Type 2 Diabetes Mellitus with dyslipidaemia

Correlation Between Glycosylated Haemoglobin and Serum Lipid Profile in Patients with Type 2 Diabetes

Introduction: Dyslipidaemia is one of the major risk factor for cardiovascular disease in Type 2 Diabetes mellitus, characterized by elevated Total cholesterol (TC), Triglycerides (TG), Low density lipoprotein (LDL) and decreased High density lipoprotein (HDL). Haemoglobin A1c (HbA1c) is widely used as an index of mean glycaemia, a measure of risk for the development of diabetes complications and a measure of the quality of diabetes care. The aim of this study was to determine the impact of glycaemic control on lipid profile and to know utility of HbA1c as an indirect indicator of dyslipidaemia. Objectives:  To assess the relationship between glycemic control (HbA1c) and serum lipid profile as well as to evaluate the importance of HbA1c as an indicator of dyslipidemia in patients with T2DM. Materials and Methods: The present study is a prospective, observational study which is conducted in the Department of General Medicine at Surabhi Institute of Medical Sciences over a period of 6 months.  A total of 65 T2DM patients with dyslipidemia who had visited the hospital. Inclusion criteria: Adults aged above 30 years and having Type 2 Diabetes Mellitus with dyslipidaemia

Characteristics of Embedded-Shock-Free Compressible Vortex Rings: A Detailed Study Using PIV

The present study focus on evolution of compressible vortex ring generated at the open end of a shock tube through accurate measurement of velocity field using Particle Image Velocimetry (PIV). To investigate the unsteady characteristics of embedded shock-free, low Mach number vortex rings, two cases (shock Mach numbers, M=1.27 and M=1.37) are considered for PIV measurements. Time-dependent variations of circulation, core and ring diameters, and ring velocity are calculated from the measured velocity field. Pinching-off process is investigated in detail for both cases. Formation time and the time of complete detachment of the vortex ring from the trailing jet are identified from the velocity and vorticity field. The ring formation is complete at about t*(=tUb/D)=1.75 and 1.65 for M=1.27 and 1.37, respectively, where t is time, Ub is fluid velocity behind the shock at exit, and D is tube diameter. Complete detachment of the vortex ring from the trailing jet is observed at t∗=2 and 2.9 for M=1.27 and 1.37, respectively