16 research outputs found
A comparative study on the in vitro effects of the DNA methyltransferase inhibitor 5-Azacytidine (5-AzaC) in breast/mammary cancer of different mammalian species
Get PDFIn vivo Comparison of the Effects of Bupivacaine and Levobupivacaine on the Pregnant Rat Myometrium Using Electrohysterogram
No full textOptimally fitted tracheal tubes decrease the probability of postextubation adverse events in children undergoing general anesthesia
No full textEffects of coupling agent addition on the adhesive wear, frictional and thermal properties of glass fiber-reinforced polyamide 6,6 composites
No full textGlycine decarboxylase induces autophagy and is downregulated by miRNA-30d-5p in hepatocellular carcinoma
No full textAutophagy inhibitor facilitates gefitinib sensitivity in vitro and in vivo by activating mitochondrial apoptosis in triple negative breast cancer
No full textA new numerical approach for low velocity impact response of multiscale-reinforced nanocomposite plates
No full text
Targeting autophagy in cancer
No full textAutophagy is a mechanism by which cellular material is delivered to lysosomes for degradation, leading to the basal turnover of cell components and providing energy and macromolecular precursors. Autophagy has opposing, context-dependent roles in cancer, and interventions to both stimulate and inhibit autophagy have been proposed as cancer therapies. This has led to the therapeutic targeting of autophagy in cancer to be sometimes viewed as controversial. In this Review, we suggest a way forwards for the effective targeting of autophagy by understanding the context-dependent roles of autophagy and by capitalizing on modern approaches to clinical trial design
A Comparative Study between the Effect of Combined Local Anesthetic and Low-dose Ketamine with Local Anesthetic on Postoperative Complications after Impacted Third Molar Surgery
No full text
