1,053 research outputs found
Modified navigation instructions for spatial navigation assistance systems lead to incidental spatial learning
© 2017 Gramann, Hoepner and Karrer-Gauss. Spatial cognitive skills deteriorate with the increasing use of automated GPS navigation and a general decrease in the ability to orient in space might have further impact on independence, autonomy, and quality of life. In the present study we investigate whether modified navigation instructions support incidental spatial knowledge acquisition. A virtual driving environment was used to examine the impact of modified navigation instructions on spatial learning while using a GPS navigation assistance system. Participants navigated through a simulated urban and suburban environment, using navigation support to reach their destination. Driving performance as well as spatial learning was thereby assessed. Three navigation instruction conditions were tested: (i) a control group that was provided with classical navigation instructions at decision points, and two other groups that received navigation instructions at decision points including either (ii) additional irrelevant information about landmarks or (iii) additional personally relevant information (i.e., individual preferences regarding food, hobbies, etc.), associated with landmarks. Driving performance revealed no differences between navigation instructions. Significant improvements were observed in both modified navigation instruction conditions on three different measures of spatial learning and memory: subsequent navigation of the initial route without navigation assistance, landmark recognition, and sketch map drawing. Future navigation assistance systems could incorporate modified instructions to promote incidental spatial learning and to foster more general spatial cognitive abilities. Such systems might extend mobility across the lifespan
The Triangle Groups (2, 4, 5) and (2, 5, 5) are not Systolic
In this paper we provide new examples of hyperbolic but nonsystolic groups by showing that the triangle groups (2, 4, 5) and (2, 5, 5) are not systolic. Along the way we prove some results about subsets of systolic complexes stable under involutions
The Characteristic Structural Features of the Blood Vessels of the Lewis Lung Carcinoma (A Light Microscopic and Scanning Electron Microscopic Study)
Vascular corrosion casts of Lewis lung carcinomas (LLC) grown subcutaneously in C57BL/6-mice are correlated with histological sections and with tumor tissue prepared for scanning electron microscopy (SEM). By making low, medium and high pressure cast preparations we studied the influence of perfusion and injection pressure on the resulting cast sample.
Three types of vascular proliferations are distinguishable in LLC: 1) Small globular outgrowths on sinusoidal dilated tumor capillaries, caused by proliferation of their endothelial cells. 2) New sprouts on surrounding host vessels, invading the small, still avascular implant. 3) Superficially located, centrifugally running sprouts in peripheral regions of large tumors. They invade the surrounding host tissue.
Vascular sprouts are of venous origin, have a fragmentary endothelium and are rather leaky if casted.
High pressure preparations of large tumors reveal central avascular cavities surrounded by centripetally running, compressed and blind ending tumor vessels.
Irrespective of the applied injection pressure, the casts always exhibit extravasal channels caused by degeneration of the endothelium of central tumor vessels.
We show that SEM of vascular corrosion casts combined with histology not only demonstrates such contrary processes as the development of tumor blood vessels and the simultaneously occurring vascular degeneration, but also elucidates all other morphological characteristics of the tumor vascular system
The Angioarchitecture of the Lewis Lung Carcinoma in Laboratory Mice (A Light Microscopic and Scanning Electron Microscopic Study)
53 Lewis lung carcinomas implanted subcutaneously into C57BL/6-mice were examined. The animals were killed at various stages of tumor growth (TG) and prepared for histology and for scanning electron microscopy (critical-point-dried tissue; vascular corrosion casts). Prior to casting animals were rinsed using different perfusion pressures. Casting was done by manual injection of the resin, whereby different influx-rates were applied resulting in low, medium and high pressure preparations.
We discern 3 phases of tumor angiogenesis (TA) occurring during 4 stages of TG among which vasodilation establishes the first reaction of the host vascular system to a growing tumor implant. During this stage 1 of TG, tumor nidation, nearby sinusoidal dilated host capillaries form globular outgrowings (phase 1 of TA) Subsequently radially arranged sprouts, which preferentially arise from venous host vessels, grow into the centre of the implant (phase 2 of TA). Stage 2 of TG, early tumor growth, is characterized by necrosis of the central tumor tissue and the development of a central avascular cavity. Thus the tumor vascular system is organized like a hollow sphere with a central cavity and a peripheral vascular envelope with large vessels embracing the tumor and centrifugally growing vascular sprouts, which arise from the venous part of the vascular envelope and invade the surrounding host tissue (phase 3 of TA). During stage 3 of TG, late tumor growth, many vessels of the basket-like vascular envelope obliterate. In stage 4 of TG, prefinal phase, the peripheral vascular density decreases continuously. Thus vascular sprouting and proliferation of viable tumor cells is confined to basal regions of the tumor
A Spectral Algorithm with Additive Clustering for the Recovery of Overlapping Communities in Networks
This paper presents a novel spectral algorithm with additive clustering
designed to identify overlapping communities in networks. The algorithm is
based on geometric properties of the spectrum of the expected adjacency matrix
in a random graph model that we call stochastic blockmodel with overlap (SBMO).
An adaptive version of the algorithm, that does not require the knowledge of
the number of hidden communities, is proved to be consistent under the SBMO
when the degrees in the graph are (slightly more than) logarithmic. The
algorithm is shown to perform well on simulated data and on real-world graphs
with known overlapping communities.Comment: Journal of Theoretical Computer Science (TCS), Elsevier, A Para\^itr
An efficient and principled method for detecting communities in networks
A fundamental problem in the analysis of network data is the detection of
network communities, groups of densely interconnected nodes, which may be
overlapping or disjoint. Here we describe a method for finding overlapping
communities based on a principled statistical approach using generative network
models. We show how the method can be implemented using a fast, closed-form
expectation-maximization algorithm that allows us to analyze networks of
millions of nodes in reasonable running times. We test the method both on
real-world networks and on synthetic benchmarks and find that it gives results
competitive with previous methods. We also show that the same approach can be
used to extract nonoverlapping community divisions via a relaxation method, and
demonstrate that the algorithm is competitively fast and accurate for the
nonoverlapping problem.Comment: 14 pages, 5 figures, 1 tabl
Effects of Contact Network Models on Stochastic Epidemic Simulations
The importance of modeling the spread of epidemics through a population has
led to the development of mathematical models for infectious disease
propagation. A number of empirical studies have collected and analyzed data on
contacts between individuals using a variety of sensors. Typically one uses
such data to fit a probabilistic model of network contacts over which a disease
may propagate. In this paper, we investigate the effects of different contact
network models with varying levels of complexity on the outcomes of simulated
epidemics using a stochastic Susceptible-Infectious-Recovered (SIR) model. We
evaluate these network models on six datasets of contacts between people in a
variety of settings. Our results demonstrate that the choice of network model
can have a significant effect on how closely the outcomes of an epidemic
simulation on a simulated network match the outcomes on the actual network
constructed from the sensor data. In particular, preserving degrees of nodes
appears to be much more important than preserving cluster structure for
accurate epidemic simulations.Comment: To appear at International Conference on Social Informatics (SocInfo)
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Self-regulated charge transfer and band tilt in nm-scale polar GaN films
To date, the generic polarization of Bernardini, Fiorentini and Vanderbilt
(PBFV) has been widely used to address the issue of polarity in III-V nitride
semiconductors, but improvements in nitride materials and the performance of
optoelectronic devices have been limited. The current first-principles
calculation for the electronic structures of nm-scale [0001] GaN films show
that the internal electric fields and the band tilt of these films are in
opposite direction to those predicted by PBFV. Additionally, it is determined
that an intrinsic self-regulated charge transfer across the film limits the
electrostatic potential difference across the film, which renders the local
conduction band energy minimum (at the Ga-terminated surface) approximately
equal to the local valence band energy maximum (at the N-terminated surface).
This effect is found to occur in films thicker than ~4nm
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