133 research outputs found
Location, orbit and energy of a meteoroid impacting the moon during the Lunar Eclipse of January 21, 2019
During lunar eclipse of January 21, 2019 a meteoroid impacted the Moon
producing a visible light flash. The impact was witnessed by casual observers
offering an opportunity to study the phenomenon from multiple geographical
locations. We use images and videos collected by observers in 7 countries to
estimate the location, impact parameters (speed and incoming direction) and
energy of the meteoroid. Using parallax, we achieve determining the impact
location at lat. , lon. and
geocentric distance as 356553 km. After devising and applying a photo-metric
procedure for measuring flash standard magnitudes in multiple RGB images having
different exposure times, we found that the flash, had an average G-magnitude
. We use gravitational ray tracing (GRT) to
estimate the orbital properties and likely radiant of the impactor. We find
that the meteoroid impacted the moon with a speed of km/s (70%
C.L.) and at a shallow angle, degrees. Assuming a normal error
for our estimated flash brightness, educated priors for the luminous efficiency
and object density, and using the GRT-computed probability distributions of
impact speed and incoming directions, we calculate posterior probability
distributions for the kinetic energy (median = 0.8 kton), body
mass ( = 27 kg) and diameter ( = 29 cm), and crater
size ( = 9 m). If our assumptions are correct, the crater left by
the impact could be detectable by prospecting lunar probes. These results arose
from a timely collaboration between professional and amateur astronomers which
highlight the potential importance of citizen science in astronomy.Comment: 19 pages, 11 figures, 4 tables. Data and scripts available in
https://github.com/seap-udea/MoonFlashes. Accepted for publication in MNRA
4
Abstract. Brain-Computer Interfaces based on electrocorticography (ECoG) or electroencephalography (EEG), in combination with robot-assisted active physical therapy, may support traditional rehabilitation procedures for patients with severe motor impairment due to cerebrovascular brain damage caused by stroke. In this short report, we briefly review the state-of-the art in this exciting new field, give an overview of the work carried out at the Max Planck Institute for Biological Cybernetics and the University of TΓΌbingen, and discuss challenges that need to be addressed in order to move from basic research to clinical studies. Current rehabilitation methods for patients with severe motor impairment due to cerebrovascular brain damage are limited in providing significant long-term functional recovery. In stroke patients, functional recovery beyond one year post-stroke is rare (Johnston et al. [2004]), and functional independence often displays a long-term decline (Dhamoon et al. [2009]). As such, novel strategies in stroke rehabilitation are required. Robot-assisted physical therapy (Riener et al. [2005]) and motor imagery (Dijkerman et al. [2004], Page et al. [2007]) have been shown to be beneficial in stroke rehabilitation
Genetic Basis of Virulence Attenuation Revealed by Comparative Genomic Analysis of Mycobacterium tuberculosis Strain H37Ra versus H37Rv
Tuberculosis, caused by Mycobacterium tuberculosis, remains a leading infectious disease despite the availability of chemotherapy and BCG vaccine. The commonly used avirulent M. tuberculosis strain H37Ra was derived from virulent strain H37 in 1935 but the basis of virulence attenuation has remained obscure despite numerous studies. We determined the complete genomic sequence of H37Ra ATCC25177 and compared that with its virulent counterpart H37Rv and a clinical isolate CDC1551. The H37Ra genome is highly similar to that of H37Rv with respect to gene content and order but is 8,445 bp larger as a result of 53 insertions and 21 deletions in H37Ra relative to H37Rv. Variations in repetitive sequences such as IS6110 and PE/PPE/PE-PGRS family genes are responsible for most of the gross genetic changes. A total of 198 single nucleotide variations (SNVs) that are different between H37Ra and H37Rv were identified, yet 119 of them are identical between H37Ra and CDC1551 and 3 are due to H37Rv strain variation, leaving only 76 H37Ra-specific SNVs that affect only 32 genes. The biological impact of missense mutations in protein coding sequences was analyzed in silico while nucleotide variations in potential promoter regions of several important genes were verified by quantitative RT-PCR. Mutations affecting transcription factors and/or global metabolic regulations related to in vitro survival under aging stress, and mutations affecting cell envelope, primary metabolism, in vivo growth as well as variations in the PE/PPE/PE-PGRS family genes, may underlie the basis of virulence attenuation. These findings have implications not only for improved understanding of pathogenesis of M. tuberculosis but also for development of new vaccines and new therapeutic agents
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