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    Rapid Synthesis of 2-Substituted-2,3-dihydro-4(1H)-quinazolinones using Boric Acid or Sodium Dihydrogen Phosphate under Solvent-Free Conditions

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    Two efficient and convenient methods have been described for synthesis of 2-substituted-2,3-dihydro-4(1H)-quinazolinoneĀ derivatives by one-pot condensation of 2-anthranilamide with aldehydes or ketones in the presence of a catalytic amount of boricĀ acid or sodium dihydrogen phosphate under solvent-free conditions. The attractive features of these processes are short reactionĀ times, easy isolation of products, excellent yields and an environmental friendly procedure.Keywords:Ā Dihydroquinazolinones, boric acid, sodium dihydrogen phosphate, 2-anthranilamide, solvent-free synthesi
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