The role of warmed intravenous fluid on intraoperative hypothermia and postoperative shivering during prolonged oral and maxillofacial surgery

Background: Under general anaesthesia, the core temperature may drop up to 6°C. Patients undergoing prolonged maxillofacial surgery frequently experience unintentional hypothermia that causes postanaesthetic shivering which is a common complication of anaesthesia that should be prevented. This study aimed to evaluate the role of warmed intravenous fluid in preventing intraoperative hypothermia and postoperative shivering. Methods: Between January 2022 and December 2022, 322 patients with American Society of Anesthesiologists (ASA) physical status I, II and the age group of 18 to 45 years old scheduled for elective major oral and maxillofacial surgery were evaluated under the Department of Anaesthesiology in Dhaka Dental College and Hospital. The patients were grouped into Room Temperature Group and Warmed Fluid Group. Results: 162 patients received warmed fluid, whereas 160 patients received fluid at room temperature. In Room Temperature Group, there were 89 male and 71 female patients, whereas Warmed Fluid group had 88 male and 74 female patients. At the end of the procedure, the basal core temperature was 36.7±0.2°C in the group receiving warmed fluid versus 35.9±0.2°C in the group receiving fluid at room temperature. The incidence of hypothermia (<36 °C) was much lower in Warmed Fluid Group (n=28, 17.28%) than Room Temperature Group (n=86, 53.75%). Shivering was more common in Room Temperature Group (n = 67, 41.86%) than in Warmed Fluid Group (n = 19, 11.73%) in the postanaesthetic care unit (PACU). Conclusions: The results of this study suggested that intraoperative hypothermia and postoperative shivering are less common when warmed fluid is infused.  

Integration of herbicides with manual weeding for controlling the weeds in rice under saline environment

The pot experiment was conducted to select appropriate integrated weed management method in rice under different salinity levels (0,4 and 8 dS m-1). All the parameters including rice and weed measured were significantly influenced by weed control treatments at all salinity levels. Treatments including weed-free condition, Pretilachlor @ 0.375 kg ai ha-1 + hand weeding, Propanil + Thiobencarb @ 0.9 kg ai ha-1 and 1.8 kg ai ha-1 + hand weeding performed better under all salinity levels. Pretilachlor @ 0.375 kg ai ha-1 with one round of hand weeding and propanil + thiobencarb 0.9 kg ai ha-1 + 1.8 kg ai ha-1 with one round of hand weeding were comparable to weed-free yields, and were superior to other treatments under salinity condition. Considering all the parameters, pretilachlor @ 0.375 kg ai ha-1 + one round of hand weeding (at 65 DAT), propanil + thiobencarb 0.9 kg ai ha-1 +1.8 kg ai ha-1 + one round of hand weeding (at 65 DAT) gave the most effective control of weeds in rice under saline environments

Effect of salt stress on morpho-physiology, vegetative growth and yield of rice

Selection of salt tolerant rice varieties has a huge impact on global food supply chain. Five Malaysian rice (Oryza sativa L.) varieties, MR33, MR52, MR211, MR219 and MR232 were tested in pot experiment under different salinity levels for their response in term of vegetative growth, physiological activities, development of yield components and grain yield. Rice varieties, BRRI dhan29 and IR20 were used as a salt-sensitive control and Pokkali was used as a salt-tolerant control. Three different salinity levels viz. 4, 8, and 12 dS m-1 were used in a randomized complete block design with four replications under glass house conditions. Two Malaysia varieties, MR211 and MR232 performed better in terms of vegetative growth (plant height, leaf area plant-1, number of tillers plant-1, dry matter accumulation plant-1), photosynthetic rate, transpiration rate, yield components, grain yield and injury symptoms. While, MR33, MR52 and MR219 verities were able to withstand salinity stress over salt-sensitive control, BRRI dhan29 and IR20

Coronavirus disease 2019 and future pandemics: Impacts on livestock health and production and possible mitigation measures

The World Health Organization declared coronavirus disease 2019 (COVID-19) a pandemic on March 11, 2020. COVID-19, the current global health emergency, is wreaking havoc on human health systems and, to a lesser degree, on animals globally. The outbreak has continued since the first report of COVID-19 in China in December 2019, and the second and third waves of the outbreak have already begun in several countries. COVID-19 is expected to have adverse effects on crop production, food security, integrated pest control, tourism, the car industry, and other sectors of the global economy. COVID-19 induces a range of effects in livestock that is reflected economically since human health and livelihood are intertwined with animal health. We summarize the potentially harmful effects of COVID-19 on livestock and possible mitigation steps in response to this global outbreak. Mitigation of the negative effects of COVID-19 and future pandemics on livestock requires the implementation of current guidelines

Sustainable Antibiotic-Free Broiler Meat Production: Current Trends, Challenges, and Possibilities in a Developing Country Perspective

Antibiotic-free broiler meat production is becoming increasingly popular worldwide due to consumer perception that it is superior to conventional broiler meat. Globally, broiler farming impacts the income generation of low-income households, helping to alleviate poverty and secure food in the countryside and in semi-municipal societies. For decades, antibiotics have been utilized in the poultry industry to prevent and treat diseases and promote growth. This practice contributes to the development of drug-resistant bacteria in livestock, including poultry, and humans through the food chain, posing a global public health threat. Additionally, consumer demand for antibiotic-free broiler meat is increasing. However, there are many challenges that need to be overcome by adopting suitable strategies to produce antibiotic-free broiler meat with regards to food safety and chicken welfare issues. Herein, we focus on the importance and current scenario of antibiotic use, prospects, and challenges in the production of sustainable antibiotic-free broiler meat, emphasizing broiler farming in the context of Bangladesh. Moreover, we also discuss the need for and challenges of antibiotic alternatives and provide a future outlook for antibiotic-free broiler meat production

Multidrug-resistant non-typhoidal Salmonella of public health significance recovered from migratory birds in Bangladesh

Non-typhoidal Salmonella provides an exemplar for the One Health approach as it encompasses public and animal health, food safety, and environmental considerations. The contribution of environmental aspects is currently less well-defined. The purpose of this study was to determine the carriage occurrence of non-typhoidal Salmonella in migratory birds in Bangladesh and assess the potential significance to public and animal health. Cloacal swabs (N = 453) were collected in the years 2018-2020 from Tanguar and Hakaluki Haors, important wetland ecosystems in Northeastern Bangladesh. The prevalence of Salmonella was 13.5% (61 positive swabs). Classical serotyping identified six serovars: Salmonella enterica subsp. enterica serovars Perth, Kentucky, Albany, Infantis, Weltevreden, and Brancaster. Resistance towards 14 antimicrobials was assessed by broth microdilution minimum inhibitory concentration determination and the antimicrobial resistance (AMR) genotype established by whole-genome sequencing. S. Perth and S. Weltevreden isolates were susceptible and harbored no acquired AMR genes. Isolates from the remaining serovars were multidrug resistant, commonly possessing resistance to tetracycline, ampicillin, chloramphenicol, sulfamethoxazole, trimethoprim, and ciprofloxacin. Salmonella resistant to ciprofloxacin meets WHO criteria for priority pathogens. There was excellent concordance between resistance phenotype and the presence of corresponding AMR genes, many of which reside on Salmonella Genomic Islands. High-level ciprofloxacin resistance correlated with the presence of mutations in the chromosomal gyrB and/or parC genes. The S. Kentucky isolates were ST198, a widely distributed multidrug-resistant lineage reported in humans and animals, and constituting an ongoing risk to public health worldwide. We have demonstrated that multidrug-resistant non-typhoidal Salmonella of public health significance can be recovered from migratory birds. A potential for risk can manifest through direct interaction, transmission to food-producing livestock on farms, and dissemination via the long range migratory movements of birds. Risks can be mitigated by measures including continued surveillance and implementation of good farm biosecurity practices

Allelopathic potential in rice - a biochemical tool for plant defence against weeds

Rice is a key crop for meeting the global food demand and ensuring food security. However, the crop has been facing great problems to combat the weed problem. Synthetic herbicides pose a severe threat to the long-term viability of agricultural output, agroecosystems, and human health. Allelochemicals, secondary metabolites of allelopathic plants, are a powerful tool for biological and eco-friendly weed management. The dynamics of weed species in various situations are determined by crop allelopathy. Phenolics and momilactones are the most common allelochemicals responsible for herbicidal effects in rice. The dispersion of allelochemicals is influenced not only by crop variety but also by climatic conditions. The most volatile chemicals, such as terpenoids, are usually emitted by crop plants in drought-stricken areas whereas the plants in humid zones release phytotoxins that are hydrophilic in nature, including phenolics, flavonoids, and alkaloids. The allelochemicals can disrupt the biochemical and physiological processes in weeds causing them to die finally. This study insight into the concepts of allelopathy and allelochemicals, types of allelochemicals, techniques of investigating allelopathic potential in rice, modes of action of allelochemicals, pathways of allelochemical production in plants, biosynthesis of allelochemicals in rice, factors influencing the production of allelochemicals in plants, genetical manipulation through breeding to develop allelopathic traits in rice, the significance of rice allelopathy in sustainable agriculture, etc. Understanding these biological phenomena may thus aid in the development of new and novel weed-control tactics while allowing farmers to manage weeds in an environmentally friendly manner

Construction of copy number variation landscape and characterization of associated genes in a Bangladeshi cohort of neurodevelopmental disorders

Introduction: Copy number variations (CNVs) play a critical role in the pathogenesis of neurodevelopmental disorders (NDD) among children. In this study, we aim to identify clinically relevant CNVs, genes and their phenotypic characteristics in an ethnically underrepresented homogenous population of Bangladesh. Methods: We have conducted chromosomal microarray analysis (CMA) for 212 NDD patients with male to female ratio of 2.2:1.0 to identify rare CNVs. To identify candidate genes within the rare CNVs, gene constraint metrics [i.e., “Critical-Exon Genes (CEGs)”] were applied to the population data. Autism Diagnostic Observation Schedule-Second Edition (ADOS-2) was followed in a subset of 95 NDD patients to assess the severity of autism and all statistical tests were performed using the R package. Results: Of all the samples assayed, 12.26% (26/212) and 57.08% (121/212) patients carried pathogenic and variant of uncertain significance (VOUS) CNVs, respectively. While 2.83% (6/212) patients’ pathogenic CNVs were found to be located in the subtelomeric regions. Further burden test identified females are significant carriers of pathogenic CNVs compared to males (OR = 4.2; p = 0.0007). We have observed an increased number of Loss of heterozygosity (LOH) within cases with 23.85% (26/109) consanguineous parents. Our analyses on imprinting genes show, 36 LOH variants disrupting 69 unique imprinted genes and classified these variants as VOUS. ADOS-2 subset shows severe social communication deficit (p = 0.014) and overall ASD symptoms severity (p = 0.026) among the patients carrying duplication CNV compared to the CNV negative group. Candidate gene analysis identified 153 unique CEGs in pathogenic CNVs and 31 in VOUS. Of the unique genes, 18 genes were found to be in smaller (<1 MB) focal CNVs in our NDD cohort and we identified PSMC3 gene as a strong candidate gene for Autism Spectrum Disorder (ASD). Moreover, we hypothesized that KMT2B gene duplication might be associated with intellectual disability. Conclusion: Our results show the utility of CMA for precise genetic diagnosis and its integration into the diagnosis, therapy and management of NDD patients

Eco-conscious tourism: a study on green turtle conservation measures at Pantai Kerachut, Penang

The impact of tourism on the safety of green turtle hatching at Pantai Kerachut, Penang, Malaysia has been reviewed in this paper. It emphasizes the need for sustainable ecotourism practices to protect the reproduction processes of endangered green turtles. The uncontrolled influx of tourists at Penang National Park has raised concerns about its biodiversity and ecosystem. The study aims to understand the existing situation related to tourism-based activities at Pantai Kerachut and their repercussions on green turtle reproduction. The findings reveal that while authorities are making efforts to control the number and activities of tourists to safeguard the ecosystem, room for improvement remains. Illegal activities such as night camping disrupt the hatching process of turtles, necessitating stricter monitoring. Furthermore, tourist facilities at Pantai Kerachut do not adhere to proper safety standards, particularly concerning the jetty, accessibility, sanitation, and other essential amenities. There is potential for enhancing the nesting environment for green turtles by introducing suitable vegetation along the shoreline. To address these concerns, a comprehensive review of existing tourism rules and activities based on national ecotourism policies is recommended. Specific guidelines tailored to the unique ecosystem of Penang National Forest should also be developed. Lastly, further research is proposed to investigate the hatching patterns and suitable environmental conditions for green turtles. This research also projected to define specific time durations and activities with appropriate facilities, ensuring the proper management of tourism and the preservation of the ecosystem at Pantai Kerachut

Eco-conscious tourism: a study on Green Turtle conservation measures at Pantai Kerachut, Penang

The impact of tourism on the safety of green turtle hatching at Pantai Kerachut, Penang, Malaysia has been reviewed in this paper. It emphasizes the need for sustainable ecotourism practices to protect the reproduction processes of endangered green turtles. The uncontrolled influx of tourists at Penang National Park has raised concerns about its biodiversity and ecosystem. The study aims to understand the existing situation related to tourism-based activities at Pantai Kerachut and their repercussions on green turtle reproduction. The findings reveal that while authorities are making efforts to control the number and activities of tourists to safeguard the ecosystem, room for improvement remains. Illegal activities such as night camping disrupt the hatching process of turtles, necessitating stricter monitoring. Furthermore, tourist facilities at Pantai Kerachut do not adhere to proper safety standards, particularly concerning the jetty, accessibility, sanitation, and other essential amenities. There is potential for enhancing the nesting environment for green turtles by introducing suitable vegetation along the shoreline. To address these concerns, a comprehensive review of existing tourism rules and activities based on national ecotourism policies is recommended. Specific guidelines tailored to the unique ecosystem of Penang National Forest should also be developed. Lastly, further research is proposed to investigate the hatching patterns and suitable environmental conditions for green turtles. This research also projected to define specific time durations and activities with appropriate facilities, ensuring the proper management of tourism and the preservation of the ecosystem at Pantai Kerachut