The effect of dietary lipid on the growth performance of Meagre (Argyrosomus regius Asso, 1801)

The aim of the study was to investigate the effects of dietary lipid on the growth and feed utilization of Meagre (Argyrosomus regius Asso, 1801), taking into account their feeding behavior of collecting food from the bottom of the cages. The fish (141.07±0.5g, average weight ± SD; 22.18±0.53 cm, average total length± SD) were fed three isonitrogenous experimental diets (45% crude protein, dry matter) containing 16% (group A), 18% (group B), and 20% (group C) crude lipids for 570 days. The fish were stocked into 9 net cages (16 m diameter; 7 m deep) at a density of 16000 fish per cage with 2 replications. At the end of the experiment fish in the A, B, and C groups reached 1054.59±5.9, 1026.32±4.3, 955.31±2.3 mean live weight (g) and 45.78±1.6, 44.43±1.4, 43.88±1.4 mean total length (cm) respectively. FCR and CF values were 1.99, 2.07, 2.14 and 1.999, 1.131, 1.170 respectively for each group, at the end of the study. VSI, HIS, and GSI values were also calculated. Growth rate in fish from group A (fed the lowest lipid diet) was superior to the other dietary groups. Cross sections of their liver were checked and were found to have less lipidosis. © 2016, Israeli Journal of Aquaculture - Bamidgeh. All rights reserved

The prognostic significance of serum TGF-?1 levels in patients with Crimean-Congo hemorrhagic fever

PubMed: 27467498Crimean-Congo Hemorrhagic Fever (CCHF) may exhibit a mild clinical course or a severe profile like mortal bleeding. The pathogenesis of the illness and reason of bleeding are unclear. However, endothelial injury is a key factor in the pathogenesis of the illness. Transforming growth factor beta (TGF-?) is one of the materials involved in repairing injured endothelium. This is a significant polypeptide released in pretty much all cells and important for the regulation of cellular events, epithelium formation, inflammation, blood coagulation, and collagen synthesis. This study aimed to determine the prognostic significance of serum TGF-?1 levels in CCHF patients. We examined 120 patients hospitalized with CCHF diagnosis and their serum TGF-?1 was investigated, retrospectively. Patients were put into two groups according to the existence of hemorrhage. Forty-four (36.7%) patients had hemorrhage. TGF-?1 levels in patients with bleeding were 5.2 ± 1.8, and 7.1 ± 2.2 for non-bleeding (P < 0.0001). When ROC analysis was performed in patients with CCHF alone in order to identify patients with bleeding, at a TGF-?1 cut-off point of 4.9, AUC was 0.762 (0.675–0.835), sensitivity 59.1%, specificity 85.5%, PPV 70.3%, and NPV 78.3%. We summarize that TGF-?1 level and endothelial dysfunction can be related. A decreased TGF-?1 level is a likely prognostic and diagnostic factor for bleeding in CCHF patients. Therefore, this marker should be considered in the treatment strategy for these patients. J. Med. Virol. 89:413–416, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc

Body mass index and complications following major gastrointestinal surgery: A prospective, international cohort study and meta-analysis

Aim Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a metaanalysis of all available prospective data. Methods This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien–Dindo Grades III–V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastrointestinal surgery. Individual patient meta-analysis was used to analyse pooled results. Results This study included 2519 patients across 127 centres, of whom 560 (22.2%) were obese. Unadjusted major complication rates were lower in obese vs normal weight patients (13.0% vs 16.2%, respectively), but this did not reach statistical significance (P = 0.863) on multivariate analysis for patients having surgery for either malignant or benign conditions. Individual patient meta-analysis demonstrated that obese patients undergoing surgery formalignancy were at increased risk of major complications (OR 2.10, 95% CI 1.49–2.96, P < 0.001), whereas obese patients undergoing surgery for benign indications were at decreased risk (OR 0.59, 95% CI 0.46–0.75, P < 0.001) compared to normal weight patients. Conclusions In our international data, obesity was not found to be associated with major complications following gastrointestinal surgery. Meta-analysis of available prospective data made a novel finding of obesity being associated with different outcomes depending on whether patients were undergoing surgery for benign or malignant disease