Din felsefesi bağlamında Aziz Nesin'de ateizmin dayanakları

xi, 116 sayfa29 cm. 1 CDÖZETDin Felsefesi Bağlamında Aziz Nesin'de Ateizmin Dayanakları adlı bu çalışmada Aziz Nesin'in İslamiyet özelinde Tanrı ve dini inançlara karşı eleştirileri ele alınacaktır. Nesin, çeşitli türlerdeki yazıları ile önemli bir okuyucu kitlesine sahip olmuştur, hala da sahiptir. Bu nedenle, onun İslam inancına yönelik eleştirel bakış ve değerlendirmeleri, dar anlamıyla felsefi yöntem ve argümantasyon gözetilerek kaleme alınmadıysa da iddiaları ve bunların okuyucular üzerindeki etkisi düşünüldüğünde felsefi bir değerlendirmeye ihtiyaç göstermektedir. Bunun bir sonucu olarak bu araştırmada Nesin'in ateizmi, hayat hikâyesine ve yazılarına bakılarak anlaşılmaya ve felsefi bakış açısı ile temellendirilmeye çalışılacaktır.ABSTRACTWith the title of 'The Foundation of Aziz Nesin's Atheism in the Context of Philosophy of Religion', this thesis comprises of Aziz Nesin's criticism of theistic and religious faith, with the special reference to Islam. By employing a variety of literary genres, Nesin's writings attracted wide audience in the past, as well as it still does today. Even though his critical regard and evaluation of Islam is devoid of a proper philosophical argumentation and methodology in a technical sense, the fact that his writings exercised an enormous influence on the readers warrants for a philosophical assessment of his ideas. Accordingly, in this thesis I intend to unearth the philosophical value of Nesin's atheism, with special reference to his autobiographical writings

A* Orthogonal Matching Pursuit: Best-First Search for Compressed Sensing Signal Recovery

Compressed sensing is a developing field aiming at reconstruction of sparse signals acquired in reduced dimensions, which make the recovery process under-determined. The required solution is the one with minimum $\ell_0$ norm due to sparsity, however it is not practical to solve the $\ell_0$ minimization problem. Commonly used techniques include $\ell_1$ minimization, such as Basis Pursuit (BP) and greedy pursuit algorithms such as Orthogonal Matching Pursuit (OMP) and Subspace Pursuit (SP). This manuscript proposes a novel semi-greedy recovery approach, namely A* Orthogonal Matching Pursuit (A*OMP). A*OMP performs A* search to look for the sparsest solution on a tree whose paths grow similar to the Orthogonal Matching Pursuit (OMP) algorithm. Paths on the tree are evaluated according to a cost function, which should compensate for different path lengths. For this purpose, three different auxiliary structures are defined, including novel dynamic ones. A*OMP also incorporates pruning techniques which enable practical applications of the algorithm. Moreover, the adjustable search parameters provide means for a complexity-accuracy trade-off. We demonstrate the reconstruction ability of the proposed scheme on both synthetically generated data and images using Gaussian and Bernoulli observation matrices, where A*OMP yields less reconstruction error and higher exact recovery frequency than BP, OMP and SP. Results also indicate that novel dynamic cost functions provide improved results as compared to a conventional choice.Comment: accepted for publication in Digital Signal Processin

Sarkoid donjeg očnog kapka kod magarca (Equus asinus) izazvan bovinim papiloma 2 virusom

Sarcoid tumors were described by means of histopathological and molecular procedures in a 5-year-old donkey. Histopathological examination showed epithelial changes including hyperkeratosis, epithelial hyperplasia, koilocytosis, and rete peg formation. Neoplastic fibroblastic cells were plumb, large spindle to stellate and embedded in dense collagenous tissue. Results of Polymerase Chain Reaction and DNA sequence analysis showed that the etiological agent belonged to Bovine Papilloma Virus-II species in the delta papilloma virus genus. This case study represents the first report demonstrating the presence of Bovine Papilloma Virus-II in donkey sarcoid.Sarkoidi su opisani primenom histopatoloških i molelularanih metoda i procedura kod magarca, starog pet godina. Histopatološko ispitivanje, ukazalo je na promene u epitelu koje su uključivale hiperkeratozu, hiperplaziju epitela, koilocitozu i formiranje invaginacija epitela ptema dubokom dermisu - rete peg. Fibroblastine neoplastične ćelije su bile krupne, ovalnovretenaste i zvezdaste, uronjene u tkivo bogato kolagenom. Ispitivanje PCR metodom kao i rezultati DNK sekvencioniranja pokazali su da je etiološki agens spadao u grupu bovinog papilomavirusa-2 koji pripada rodu delta papilomavirusa. Ova studija predstavlja prvi opisani slučaj prisustva papiloma virusa goveda-2 kod sarkoida magarca

Association Between Atherogenic Index of Plasma and Atherogenic Coefficient and in-Stent Restenosis After Drug-eluting Stent Implantation for Stable Coronary Artery Disease

Introduction:Despite improvements in stent science, in-stent restenosis (ISR) remains a major problem. This study was designed to evaluate the atherogenic index of plasma (AIP) and atherogenic coefficient (AC) levels and their predictive values in patients who developed ISR after drug-eluting stent implantation for stable coronary artery disease.Methods:One hundred ninety-nine patients with ISR and 377 without ISR were included in the study. The biochemical and hematological parameters of the patients were measured. The AIP and AC values were calculated.Results:Patients with ISR had significantly longer stent length, lower stent diameter, lower ejection fraction, and higher SYNTAX score. They also had significantly higher levels of low-density lipoprotein cholesterol (LDL-C), triglyceride (TG), total cholesterol, AIP, and AC compared to that of patients who did not develop ISR. AIP had a sensitivity of 61.3% and specificity of 72.1% for predicting ISR a cut-off value of 0.58. AC had sensitivity and specificity of 69.8% and 58.8%, respectively, for the presence of ISR a cut-off value of 3.44. LDL-C level of 111.5 mg/dL had sensitivity and specificity of 65.3% and 54% for developing ISR, respectively. Paired comparisons of area difference under the receiver operating characteristic curve showed that AIP and AC had significantly greater area compared with that of LDL-C. Stent diameter, stent length, SYNTAX score, ejection fraction, AIP, and AC were the predictors of ISR.Conclusion:AIP and AC had higher specificities compared with that of LDL-C in predicting ISR. The calculation of AIP and AC is simple and could be used easily in clinical practice

The histopathological evaluation of effects of application of the bovine amniotic fluid with graft on peri-implant bone regeneration

This study aimed to determine the effects of bovine amniotic fluid combined with bone graft in treating peri-implant bone defects with guided bone regeneration. Twenty female Sprague–Dawley rats were divided into two groups. Bone sockets with a diameter of 4 mm in the coronal part and a diameter of 2.5 mm in the apical part of the implant were created into the corticocancellous bone in the metaphyseal parts of the right tibia bones of all subjects. Implants with a length of 4 mm and a diameter of 2.5 mm were placed in the bone sockets. In the sham surgery group (n = 10) was the circumferential bone defect equivalent to half of the 4-mm implant length, which occurred between the implant and the bone, filled with bovine xenograft. Bovine xenografts were filled with amniotic fluid mixture in the experimental group (n = 10). After 8 weeks of recovery, all rats were sacrificed. The implants were extracted from the soft tissues and the surrounding bone. Subsequently, the bones were decalcified and prepared for histological analysis. The percentage of newly regenerated bone (NRB) formation and fibrosis in the bone defect area around the implant was calculated from all sections. NRB was found in 37.4±4.4% of controls and 41.4±2.63% of test animals (P<0.05 and P=0.024, respectively). Fibrosis formation was found at a rate of 38.6±5.06% in the control group and 33.2±5.38% in the test group (P<0.05 and P=0.033, respectively). It was considered that combining bovine amniotic fluid with bone transplant could be a useful way of treating bone abnormalities

Comparison of Voice Quality and Cost Effectiveness of Endoscopic Cordectomy Using Microdissection Electrodes with Laser Cordectomy and Radiotherapy

Objective: To compare the acoustic parameters and the cost effectiveness achieved after endoscopic cordectomy using radiofrequency microdissection electrodes (ECRM) with those of transoral laser cordectomy and radiotherapy.Methods: The study included 81 disease-free patients previously treated for early larynx carcinoma (30 with ECRM, 27 with transoral laser cordectomy, 24 with primary radiotherapy). Post-treatment voice analysis was performed in all patients. Additionally, the cost effectiveness of all treatment procedures was calculated.Results: The GRBAS (G: Grade, R: Roughness, B: Breathiness, A: Asthenia, and S: Strain) scale showed a significant difference between the groups (p0.05 for all). Percent jitter, percent shimmer and fundamental frequency (F0) were significantly different in the radiotherapy group than the ECRM and the transoral laser cordectomy groups (p0.05). The mean cost of the ECRM technique was statistically lower than the other treatment techniques (p<0.05). Moreover, the length of hospital stay after ECRM was statistically significantly shorter than was after laser cordectomy (p<0.05).Conclusion: Objective and perceptive voice analysis after ECRM showed comparable results with transoral laser cordectomy, but poorer results than radiotherapy. Cost effectiveness of ECRM was found to be better than the other two treatment techniques

Diffusion tensor imaging and diffusion-weighted imaging on axillary lymph node status in breast cancer patients

PURPOSEThis article will examine the usefulness of diffusion tensor imaging (DTI) and diffusion-weighted imaging (DWI) on the assessment of axillary lymph nodes (ALN) of breast cancer patients.METHODSAxillary lymph nodes in 66 breast cancer patients were examined by DTI and DWI, and the largest lymph node with increased cortical thickness in axilla was selected. Morphological features, apparent diffusion coefficient (ADC), volume anisotropy, and fractional anisotropy values were measured by using a special software. Imaging findings and histopathological results were recorded.RESULTSMetastatic ALN were detected in 43 (65.1%) patients. Cortical thickness of the metastatic ALN was significantly higher than the non-metastatic ALNs (P < .001), and the long-axis-to-shortaxis ratio was significantly lower in metastatic ALNs (P < .001). There was a statistically significant difference between the ALN status and fatty hilum presence (P < .001). Apparent diffusion coefficient values of metastatic ALNs were statistically lower than those of non-metastatic ALNs (P < .001) using a cutoff value of 1.26 × 10−3 mm2 /s for b=500 ADC and 1.21 × 10−3 mm2 /s for b=800 ADC which had 97.7% sensitivity and 91.3% specificity. Fractional anisotropy and volume anisotropy values were significantly different between both groups. A cutoff value of 0.47 for b-500 fractional anisotropy had 83.7% sensitivity, 69.6% specificity 69.6% positive predictive value, and 83.7% negative predictive value. A cutoff value of 0.33 for b=500 volume anisotropy had 76.7% sensitivity, 78.3% specificity, 86.8% positive predictive value, and 64.3% negative predictive value.CONCLUSIONApparent diffusion coefficient value of metastatic ALNs was found to be significantly lower than those of non-metastatic ALN, and DTI metrics of metastatic ALN were found to be significantly higher than those of non-metastatic ALN. Overall, ADC had a better diagnostic performance than morphological features, fractional anisotropy, and volume anisotropy. Diffusion tensor imagingderived diffusion metrics may be used to complement breast magnetic resonance imaging in the future after further standardization of the imaging parameters

The positioning performance of low-cost GNSS receivers in the Precise Point Positioning method

Satellite-based positioning, which started being developed in the mid-1960s for military purposes, is now used in almost every area. For the studies single and/or double frequency receivers are used. The cost of a receiver and antenna couple that have capable of high coordinate accuracies ranges from $3000 to$15000. With the production of Original Equipment Manufacturer (OEM) receivers, the cost of satellite-based location determination decreases to approximately one in 10 for the civilian user compared to the operations performed with geodetic receivers and antennas. However, although these receivers collect data in multi-Global Navigation Satellite System (GNSS) and frequencies, the accuracy of the coordinate values estimated is not as high as geodetic receivers and antennas. Therefore, it is necessary to carry out an accuracy study to obtain information about which studies can be used in. In this study, measurements were made at the UZEL point located on the roof of the Yıldız Technical University Geomatics Engineering Department by using the ZED-F9P-02B OEM multi GNSS receiver and ANN-MB L1/L2 multi-band GNSS patch antenna. The performance of the test results has been examined by comparing the results from CSRS(Canadian Spatial Reference System)-PPP with the coordinates of the UZEL point. As a result of the comparison, the difference between the coordinate determined with collected 3.5 hr data and the coordinates of the UZEL point has been determined as – 1.4 cm, 2.8 cm, and 9.3 cm in the East, North, and Height directions, respectivel