Asymptotic Giant Branch models at very low metallicity

In this paper we present the evolution of a low mass model (initial mass M=1.5 Msun) with a very low metal content (Z=5x10^{-5}, equivalent to [Fe/H]=-2.44). We find that, at the beginning of the AGB phase, protons are ingested from the envelope in the underlying convective shell generated by the first fully developed thermal pulse. This peculiar phase is followed by a deep third dredge up episode, which carries to the surface the freshly synthesized 13C, 14N and 7Li. A standard TP-AGB evolution, then, follows. During the proton ingestion phase, a very high neutron density is attained and the s-process is efficiently activated. We therefore adopt a nuclear network of about 700 isotopes, linked by more than 1200 reactions, and we couple it with the physical evolution of the model. We discuss in detail the evolution of the surface chemical composition, starting from the proton ingestion up to the end of the TP-AGB phase.Comment: Accepted for Publication on PAS

Are Neutron-Rich Elements Produced in the Collapse of Strange Dwarfs ?

The structure of strange dwarfs and that of hybrid stars with same baryonic number is compared. There is a critical mass (M~0.24M_sun) in the strange dwarf branch, below which configurations with the same baryonic number in the hybrid star branch are more stable. If a transition occurs between both branches, the collapse releases an energy of about of 3x10^{50} erg, mostly under the form of neutrinos resulting from the conversion of hadronic matter onto strange quark matter. Only a fraction (~4%) is required to expel the outer neutron-rich layers. These events may contribute significantly to the chemical yield of nuclides with A>80 in the Galaxy, if their frequency is of about one per 1500 years.Comment: Accepted for publication in IJMP

The s-process branching at 185W

The neutron capture cross section of the unstable nucleus 185W has been derived from experimental photoactivation data of the inverse reaction 186W(gamma,n)185W. The new result of sigma = (687 +- 110) mbarn confirms the theoretically predicted neutron capture cross section of 185W of sigma = 700 mbarn at kT = 30 keV. A neutron density in the classical s-process of n_n = (3.8 +0.9 -0.8} * 1e8 cm-3 is derived from the new data for the 185W branching. In a stellar s-process model one finds a significant overproduction of the residual s-only nucleus 186Os.Comment: ApJ, in pres

Age-dependent differences in demographics, risk factors, co-morbidity, etiology, management, and clinical outcome of acute ischemic stroke

Background : Comparisons between younger and older stroke patients including comorbidities are limited. Methods : Prospective data of consecutive patients with first ever acute ischemic stroke were compared between younger (≤ 45 years) and older patients (> 45 years). Results : Among 1004 patients, 137 (14 %) were ≤ 45 years. Younger patients were more commonly female (57 % versus 34 %; p < 0.0001), had a lower frequency of diabetes (1 % versus 15 %; p < 0.0001), hypercholesterolemia (26 % versus 56 %; p < 0.0001), hypertension (19 % versus 65 %; p < 0.0001), coronary heart disease (14 % versus 40 %; p < 0.0001), and a lower mean Charlson co-morbidity index (CCI), (0.18 versus 0.84; p < 0.0001). Tobacco use was more prevalent in the young (39 % versus 26 %; P < 0.0001). Large artery disease (2 % versus 21 %; p < 0.0001), small artery disease (3 % versus 12 %; p = 0.0019) and atrial fibrillation (1 % versus 17 %; p = 0.001) were less common in young patients, while other etiologies (31 % versus 9 %; p < 0.0001), patent foramen ovale or atrial septal defect (44 % versus 26 %; p < 0.0001), and cervical artery dissection (26 % versus 7 %; p < 0.0001) were more frequent. A favorable outcome (mRS 0 or 1) was more common (57.4 % versus 46.9 %; p = 0.023), and mortality (5.1 % versus 12 %; p = 0.009) was lower in the young. After regression analysis, there was no independent association between age and outcome (p = 0.206) or mortality (p = 0.073). Baseline NIHSS score (p < 0.0001), diabetes (p = 0.041), and CCI (p = 0.002) independently predicted an unfavorable outcome. Conclusions : Younger patients were more likely to be female, had different risk factors and etiologies and fewer co-morbidities. There was no independent association between age and clinical outcome or mortalit

The effect of 12C + 12C rate uncertainties on s-process yields

The slow neutron capture process in massive stars (the weak s-process) produces most of the s-only isotopes in the mass region 60 < A < 90. The nuclear reaction rates used in simulations of this process have a profound effect on the final s-process yields. We generated 1D stellar models of a 25 solar mass star varying the 12C + 12C rate by a factor of 10 and calculated full nucleosynthesis using the post-processing code PPN. Increasing or decreasing the rate by a factor of 10 affects the convective history and nucleosynthesis, and consequently the final yields.Comment: Conference proceedings for the Nuclear Physics in Astrophysics IV conference, 8-12 June 2009. 4 pages, 3 figures. Accepted for publication to the Journal of Physics: Conference Serie

Mitochondrial neurogastrointestinal encephalomyopathy in three siblings: Clinical, genetic and neuroradiological features

Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a rare autosomal recessive disorder in which a nuclear mutation of the thymidine phosphorylase (TP) gene causes mitochondrial genomic dysfunction. Patients suffer from gastrointestinal dysmotility, cachexia, ptosis, external ophthalmoparesis, myopathy and polyneuropathy. Magnetic resonance imaging (MRI) shows leukoencephalopathy. We describe clinical, genetic and neuroradiological features of three brothers affected with MNGIE. Clinical examination, laboratory analyses, MRI and magnetic resonance spectroscopy (MRS) of the brain, and genetic analysis have been performed in all six members of the family with the three patients with MNGIE. Two of them are monozygous twins. They all suffered from gastrointestinal dysmotility, cachexia, ophthalmoplegia, muscular atrophies, and polyneuropathy. Urinary thymidine was elevated in the patients related to the severity of clinical disease, and urinary thymidine (normally not detectable) was also found in a heterozygous carrier. Brain MRI showed leukoencephalopathy in all patients; however, their cognitive functioning was normal. Brain MRS demonstrated reduced N-acetylaspartate and choline in severely affected areas. MRI of heterozygous carriers was normal. A new mutation (T92N) in the TP gene was identified. Urinary thymidine is for the first time reported to be detectable in a heterozygous carrier. MRS findings indicate loss of neurons, axons, and glial cells in patients with MNGIE, but not in heterozygous carrier

Novel method to study neutron capture of U 235 and U 238 simultaneously at keV energies

The neutron capture cross sections of the main uranium isotopes, U235 and U238, were measured simultaneously for keV energies, for the first time by combining activation technique and atom counting of the reaction products using accelerator mass spectrometry. New data, with a precision of 3%-5%, were obtained from mg-sized natural uranium samples for neutron energies with an equivalent Maxwell-Boltzmann distribution of kT∼25keV and for a broad energy distribution peaking at 426 keV. The cross-section ratio of U235(n,γ)/U238(n,γ) can be deduced in accelerator mass spectrometry directly from the atom ratio of the reaction products U236/U239, independent of any fluence normalization. Our results confirm the values at the lower band of existing data. They serve as important anchor points to resolve present discrepancies in nuclear data libraries as well as for the normalization of cross-section data used in the nuclear astrophysics community for s-process studies