Extension of Resistance Law by Approximated Function for Trajectory

An attempt has been made to extend the approximated function beyond 914 m/sec. With the help of suitable functions to enable the trajectory computation of the projectile without using the retardation coefficients from 1940 Resistance Law Tables. The results obtained with these functions have been compared with those obtained from Primary and Secondary, Ballistic Functions and using associated values defined in Siacci's method

Optimization Problem of Mortar Barrel and Bomb Clearances

Optimum mortar windage to achieve maximum accuracy and required velocity for impacting the firing stud under two conditions of constraint is considered. These control constraints are considered to be bounded and the extremals have been studied

On Availability of a Series system with Imperfect Detectors

An n-unit series system with exponential distributions for life-times and repair-time has been considered. Each unit is equipped with a detector to detect failures. Detectors are subject to two failure modes: viz. (i) instantaneous failure i.e. it fails at the time of need when a unit fails; (ii) gradual failure i.e. it fails and gives false alarm for system failure. Steady-state availability of the system is obtained by studying the underlying system equations. Behavior of steady-state unavailability has also been studied analytically

Spontaneous laceration of spleen with hilar lymph node metastasis: a case of primary splenic mantle cell lymphoma in elderly

Mantle cell lymphoma (MCL) is a type of non-Hodgkin (B-cell) lymphoma (NHL) with manifestations ranging from indolent to aggressive disease. It arises from mantle zone or primary follicle lymphocytes and is associated with translocation t (11;14) which is seen in almost all cases. Most of the cases present at stage III/IV with hepatospenomegaly, generalized lymphadenopathy, bone marrow involvement or lymphoid polyposis. Rate of relapse is high occurring in 50-60% patients and 5-year survival rates are low ~27-30%. Median overall survival is 3.5 years. Age >60 years, raised serum LDH, high mitotic count, Ki67>30%, blastoid or pleomorphic variants, TP53 mutation, gains in 3q,11q and deletions of 13q as well as 17p are important prognostic factors associated with worst outcome. Treatment involves conventional chemo-immunotherapy and stem cell transplantation (SCT). In our case the elderly patient had an atraumatic splenic rupture with no past medical history of trauma. The patient presented to the emergency department with severe abdominal pain in left upper quadrant. Thus emergency splenectomy was executed successfully, and the patient was stabilized. After receiving initial cycle of R-CHOP regime, he was lost to follow up. In this case report, we will discuss the clinical presentation, as well as current treatment guidelines for atraumatic splenic rupture

Orthodontic repositioning of traumatically intruded permanent incisors - A report of three cases

Intrusive luxation of permanent teeth is one of the most serious traumatic dental injuries involving damage to the gingival tissue, periodontal ligament, cementum, bone and to the neurovascular supply of the pulp. In addition to disruption of normal tooth development and eruption, it can also lead to pulpal necrosis, root resorption and marginal bone loss. Based on the extent/severity, intrusion maybe classified into mild (<3 mm), moderate (3-6mm) and severe (>6mm). Available techniques for managing intrusive luxation include a wait-and-watch approach to allow for spontaneous re-eruption, orthodontic traction and surgical repositioning. The type of treatment approach employed depends upon the stage of root development, severity of intrusive luxation and the presence or absence of alveolar fractures. It is difficult to predict reliable outcomes with these approaches, since the presence of variables such as the severity of intrusion, associated crown/root fracture, stage of root development and presence of alveolar fractures may alter the prognosis. The present article presents a series of three cases with intrusive luxation of permanent incisors successfully treated using an interdisciplinary approach involving orthodontic traction along with endodontic rehabilitation

A case report of all-trans retinoic acid-induced pseudotumor cerebri in an adult patient of acute promyelocytic leukemia

All-trans retinoic acid (ATRA), a derivative of vitamin A, is the first line drug for acute promyelocytic leukemia (APL). At the same time, ATRA is also associated with various side effects, including some life threatening conditions. We describe a case of ATRA-induced pseudotumor cerebri in an adult patient of APL

Cathodoluminescence Studies of Nanoindented CdZnTe Single Crystal Substrates for Analysis of Residual Stresses and Deformation Behaviour

Nanoindentation-induced residual stresses were analysed on (111) Te face CdZnTe single-crystal substrates in this study. CdZnTe substrates were subjected to nanoindentation using cube corner indenter geometry with a peak load of 10 mN. Loading rates of 1 mN/s and 5 mN/s were used in the experiments, with a holding time of 10 s at peak load. Residual stresses on the indented region were analysed from load-displacement curves and explained using dislocation generation and elastic recovery mechanisms. Residual stresses were found to be of compressive type, just on the indented surface. The slip lines along the slip directions of this material were clearly visible in the FE-SEM images of the indents. Indents and surrounding surfaces were characterized using the Cathodoluminescence (CL) technique. CL mapping of the indented surface revealed the dislocation generation and their propagation behaviour just beneath the indenter as well as in the surrounding surfaces. The dislocations act as non-radiative recombination centres and quench the CL intensity locally. Dark lines were explained as the presence of dislocations in the material. CL mapping analysis shows that both the rosette glide and tetrahedral glide of dislocations are the primary deformation mechanisms present in CdZnTe. A rosette structure was observed in the CL mapping. CL spectra at 300 K of un-deformed CdZnTe show a peak at 810 nm wavelength, which corresponds to near-band-edge emission. After indentation, the CL spectra show the peak intensity at 814 nm and 823 nm wavelengths at the edge of the indents created with a loading rate of 1 mN/s and 5 mN/s, respectively. These peak shifts from 810 nm were attributed to the tensile residual stresses present in the indented material

Bulk Disposal of Unserviceable Toxic Cresylic Acid Waste Using Polymerisation Technique

A bulk amount of unserviceable toxic cresylic acid waste has been disposed off in a safe and environmentally benign manner. A process to immobilize this waste into non-toxic solid cresol formaldehyde polymer has been developed. Initial study was performed for 1.0 Kg batch size for optimizing the process parameters and conditions, and on the basis of this data, process was scaled-up for bulk disposal (100 Kg / batch). The effect of ratio of reactants, type of catalyst [H2SO4, NaOH and Ca(OH)2], catalyst concentration, reaction temperature and reaction time have been studied in a batch process. Maximum immobilization in the 1.0 Kg batch studies was obtained when cresylic acid and formaldehyde were taken in a molar ratio 1 : 1.5 using NaOH as a catalyst. For bulk polymerization, a ratio of 1.0 : 1.2 (cresylic acid : formaldehyde) with NaOH {0.7 % (wt. / wt. of total charge)} was found optimum. The final polymerized product has been buried as per standard procedure in two brick lined pits and finally, the site has been declared as free from the toxic waste.Defence Science Journal, 2011, 61(5), pp.505-511, DOI:http://dx.doi.org/10.14429/dsj.61.51

DESIGN, DEVELOPMENT AND EVALUATION OF LIPID BASED TOPICAL FORMULATIONS OF SILVER SULFADIAZINE FOR TREATMENT OF BURNS AND WOUNDS

Abstract: The aim of this research was to develop a novel lipid based film forming gel based on polymer and to investigate its potential as slow-release wound healing vehicle. The lipid based is composed of water soluble gel with model drug (Silver Sulfadiazine) and an egg oil, which acted as a remove scars. The morphology, rheology, mechanical properties, in-vitro drug release profiles were investigated. A smooth film layers was produced. The characterization results showed that film has superior mechanical and rheological properties than the ointment and cream. The lipid based gel treating low suppurating wounds and suitable for slow release application on wound surfaces. The lipid based gel also provided a significant higher healing rate in-vivo, with well-formed epidermis with faster granulation tissue formation when compared to the controls. In conclusions, a novel polymer-based lipid film gel was developed and results suggested that they can be exploited as slow-release wound dressings. Key Words: Wound healings, slow release, silver sulfadiazine and film ge