The Valuation of Cash Flow Forecasts: An Empirical Analysis

This paper compares the market value of highly leveraged transactions (HLTs) to the discounted value of their corresponding cash flow forecasts. These forecasts are provided by management to investors and shareholders in 51 HLTs completed between 1983 and 1989. Our estimates of discounted cash flows are within 10%, on average, of the market values of the completed transactions. Our estimates perform at least as well as valuation methods using comparable companies and transactions. We also invert our analysis and estimate the risk premium implied by transaction values and forecast cash flows, and the relation of the implied risk premium to firm-level betas, industry-level betas, firm size, and firm book-to-market ratios.

Cancer Molecular Analysis Project: Weaving a rich cancer research tapestry

AbstractThe Cancer Molecular Analysis Project (CMAP) of the NCI is integrating diverse cancer research data to elucidate fundamental etiologic processes, enable development of novel therapeutic approaches, and facilitate the bridging of basic and clinical science

THE EFFECTS OF UPLEDGER CRANIOSACRAL THERAPY ON POST TRAUMATIC STRESS DISORDER SYMPTOMATOLOGY IN VIETNAM COMBAT VETERANS

The Upledger Institute has provided rwo week intensive treatment for Vietnam veterans suffering from Post Traumatic Stress Disorder as diagnosed by the Veteran's Affairs (VA) medical division. These patients received psychological evaluation tests at the times of entry and exit into and out of the program. The intensive treatment was about six-seven hours per day for eight full days, with approximately three-four hours on the first and last days of the program. The therapy used was primarily CranioSacral Therapy and its progeny Energy Cyst Release, SomatoEmotional Release and Therapeutic Imagery and Dialogue. The results obtained strongly suggest that PTSD may be more successfully treated when the thetapy includes corrections of the craniosacral system, the release of foreign energies and conscious-nonconscious integration

Tenofovir-Associated Nephrotoxicity in Two HIV-Infected Adolescent Males

We report two cases of tenofovir (TDF)-associated nephrotoxicity in perinatally HIV-infected adolescents. The first case, a 16-year-old African American male with an absolute CD4+ cell count of 314 cells/mm3, presented with an abrupt rise in serum creatinine leading to irreversible renal failure while on TDF-containing highly active antiretroviral therapy (HAART). While the patient had evidence of underlying kidney disease, the timing of his renal failure indicates that TDF played a central role. The second case, a 16-year-old African-American male with an absolute CD4+ cell count of 895 cells/mm3, presented with rickets and hypophosphatemia while receiving TDF-based HAART. To our knowledge, these cases represent the first reports of TDF-associated irreversible renal failure and rickets in pediatric patients. We believe these cases highlight important and potentially irreversible side effects of this agent and emphasize the need for further studies of the renal safety of TDF in pediatric patients

Cognitive-Behavioral Treatment of the Paraphilias

AbstrAct Background: Sexual offenders continue to occupy the public's attention; a significant proportion of this population is diagnosed with paraphilias. Cognitivebehavioral treatment has been the mainstay of treatment for sex offenders and for the paraphilias for the past three decades. This article will review the history of cognitivebehavioral therapy, its techniques, and its efficacy

Watch and learn: the cognitive neuroscience of learning from others' actions

The mirror neuron system has dominated understanding of observational learning from a cognitive neuroscience perspective. Our review highlights the value of observational learning frameworks that integrate a more diverse and distributed set of cognitive and brain systems, including those implicated in sensorimotor transformations, as well as in more general processes such as executive control, reward, and social cognition. We argue that understanding how observational learning occurs in the real world will require neuroscientific frameworks that consider how visuomotor processes interface with more general aspects of cognition, as well as how learning context and action complexity shape mechanisms supporting learning from watching others

Human factors analysis of driver behavior by experimental systems methods

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/32759/1/0000130.pd