14,173 research outputs found

    Mergers at z = 1

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    Multiband images of nearby interacting pairs of galaxies, mergers, and normal field galaxies are used to simulate images of high redshift mergers by identifying distinctive morphological features. Preliminary results indicate that it is feasible for the HST to detect these high redshift objects

    Quasinormal Modes of Kerr Black Holes in Four and Higher Dimensions

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    We analytically calculate to leading order the asymptotic form of quasinormal frequencies of Kerr black holes in four, five and seven dimensions. All the relevant quantities can be explicitly expressed in terms of elliptical integrals. In four dimensions, we confirm the results obtained by Keshest and Hod by comparing the analytic results to the numerical ones.Comment: 14 pages, 7 figure

    Dna2p Helicase/Nuclease Is a Tracking Protein, Like FEN1, for Flap Cleavage during Okazaki Fragment Maturation

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    During cellular DNA replication the lagging strand is generated as discontinuous segments called Okazaki fragments. Each contains an initiator RNA primer that is removed prior to joining of the strands. Primer removal in eukaryotes requires displacement of the primer into a flap that is cleaved off by flap endonuclease 1 (FEN1). FEN1 employs a unique tracking mechanism that requires the recognition of the free 5' terminus and then movement to the base of the flap for cleavage. Abnormally long flaps are coated by replication protein A (RPA), inhibiting FEN1 cleavage. A second nuclease, Dna2p, is needed to cleave an RPA-coated flap producing a short RPA-free flap, favored by FEN1. Here we show that Dna2p is also a tracking protein. Annealed primers or conjugated biotin-streptavidin complex block Dna2p entry and movement. Single-stranded binding protein-coated flaps inhibit Dna2p cleavage. Like FEN1, Dna2p can track over substrates with a non-Watson Crick base, such as a biotin, or a missing base within a chain. Unlike FEN1, Dna2p shows evidence of a "threading-like" mechanism that does not support tracking over a branched substrate. We propose that the two nucleases both track, Dna2p first and then FEN1, to remove initiator RNA via long flap intermediates

    Generating social network data using partially described networks: an example informing avian influenza control in the British poultry industry

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    <p>Background: Targeted sampling can capture the characteristics of more vulnerable sectors of a population, but may bias the picture of population level disease risk. When sampling network data, an incomplete description of the population may arise leading to biased estimates of between-host connectivity. Avian influenza (AI) control planning in Great Britain (GB) provides one example where network data for the poultry industry (the Poultry Network Database or PND), targeted large premises and is consequently demographically biased. Exposing the effect of such biases on the geographical distribution of network properties could help target future poultry network data collection exercises. These data will be important for informing the control of potential future disease outbreaks.</p> <p>Results: The PND was used to compute between-farm association frequencies, assuming that farms sharing the same slaughterhouse or catching company, or through integration, are potentially epidemiologically linked. The fitted statistical models were extrapolated to the Great Britain Poultry Register (GBPR); this dataset is more representative of the poultry industry but lacks network information. This comparison showed how systematic biases in the demographic characterisation of a network, resulting from targeted sampling procedures, can bias the derived picture of between-host connectivity within the network.</p> <p>Conclusions: With particular reference to the predictive modeling of AI in GB, we find significantly different connectivity patterns across GB when network estimates incorporate the more demographically representative information provided by the GBPR; this has not been accounted for by previous epidemiological analyses. We recommend ranking geographical regions, based on relative confidence in extrapolated estimates, for prioritising further data collection. Evaluating whether and how the between-farm association frequencies impact on the risk of between-farm transmission will be the focus of future work.</p&gt

    Mass Spectra of N=2 Supersymmetric SU(n) Chern-Simons-Higgs Theories

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    An algebraic method is used to work out the mass spectra and symmetry breaking patterns of general vacuum states in N=2 supersymmetric SU(n) Chern-Simons-Higgs systems with the matter fields being in the adjoint representation. The approach provides with us a natural basis for fields, which will be useful for further studies in the self-dual solutions and quantum corrections. As the vacuum states satisfy the SU(2) algebra, it is not surprising to find that their spectra are closely related to that of angular momentum addition in quantum mechanics. The analysis can be easily generalized to other classical Lie groups.Comment: 17 pages, use revte

    Tracking Blade Tip Vortices for Numerical Flow Simulations of Hovering Rotorcraft

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    Blade tip vortices generated by a helicopter rotor blade are a major source of rotor noise and airframe vibration. This occurs when a vortex passes closely by, and interacts with, a rotor blade. The accurate prediction of Blade Vortex Interaction (BVI) continues to be a challenge for Computational Fluid Dynamics (CFD). Though considerable research has been devoted to BVI noise reduction and experimental techniques for measuring the blade tip vortices in a wind tunnel, there are only a handful of post-processing tools available for extracting vortex core lines from CFD simulation data. In order to calculate the vortex core radius, most of these tools require the user to manually select a vortex core to perform the calculation. Furthermore, none of them provide the capability to track the growth of a vortex core, which is a measure of how quickly the vortex diffuses over time. This paper introduces an automated approach for tracking the core growth of a blade tip vortex from CFD simulations of rotorcraft in hover. The proposed approach offers an effective method for the quantification and visualization of blade tip vortices in helicopter rotor wakes. Keywords: vortex core, feature extraction, CFD, numerical flow visualizatio

    Impurity-induced frustration in correlated oxides

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    Using the example of Zn-doped La2CuO4, we demonstrate that a spinless impurity doped into a non-frustrated antiferromagnet can induce substantial frustrating interactions among the spins surrounding it. This counterintuitive result is the key to resolving discrepancies between experimental data and earlier theories. Analytic and quantum Monte Carlo studies of the impurity-induced frustration are in a close accord with each other and experiments. The mechanism proposed here should be common to other correlated oxides as well.Comment: 4 pages, updated figures, accepted versio

    Knowledge-based monitoring of the pointing control system on the Hubble space telescope

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    A knowledge-based system for the real time monitoring of telemetry data from the Pointing and Control System (PCS) of the Hubble Space Telescope (HST) that enables the retention of design expertise throughout the three decade project lifespan by means other than personnel and documentation is described. The system will monitor performance, vehicle status, success or failure of various maneuvers, and in some cases diagnose problems and recommend corrective actions using a knowledge base built using mission scenarios and the more than 4,500 telemetry monitors from the HST
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