The effect of varying volume fraction of microcapsules on fresh, mechanical and self-healing properties of mortars

Spherical polymeric microcapsules, carrying liquid sodium silicate, were used for autonomic self-healing of mortars. Microcapsules were added at varying volume fractions (V$_f$), with respect to the cement volume, from as low as 4% up to 32% and their effect on fresh, mechanical and self-healing properties was investigated. For this purpose a series of techniques were used ranging from static mechanical testing, ultrasonic measurements, capillary sorption tests and optical microscopy. A detailed investigation was also carried out at the microstructural level utilising scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX). Results showed that although increasing V$_f$ resulted in a ~27% reduction in the mechanical properties, the corresponding improvement in the self-healing potential was significantly higher. Areal crack mouth healing reached almost 100%. Also, the measured crack depth and sorptivity coefficient reduced to a maximum of 70% and 54% respectively in microcapsule-containing specimens. SEM/EDX observations showed that the regions in the periphery of fractured microcapsules are very dense. In this region, high healing product formation is also observed. Elemental analysis revealed that these products are mainly ettringite and calcium-silicate-hydrate (C-S-H).Engineering and Physical Sciences Research Council (Project Ref. EP/K026631/1 – ‘‘Materials for Life”)This is the final version of the article. It first appeared from Elsevier via http://dx.doi.org/10.1016/j.conbuildmat.2016.06.11

Assessing the adaptation of arable farmers to climate change using DEA and bio-economic modelling

The objective of this article is to assess the impact of climate change on arable farming systems in Flevoland (the Netherlands) and to explore the adoption of different adaptation strategies. Data Envelopment Analysis (DEA) is applied that uses empirical data from individual farms to identify “best” current farm practices and derive relationships regarding current farm managemen

Penicillin kills chlamydia following the fusion of bacteria with Lysosomes and prevents genital inflammatory lesions in C. muridarum-infected mice

The obligate intracellular bacterium Chlamydia exists as two distinct forms. Elementary bodies (EBs) are infectious and extra-cellular, whereas reticulate bodies (RBs) replicate within a specialized intracellular compartment termed an ‘inclusion’. Alternative persistent intra-cellular forms can be induced in culture by diverse stimuli such as IFNγ or adenosine/EHNA. They do not grow or divide but revive upon withdrawal of the stimulus and are implicated in several widespread human diseases through ill-defined in vivo mechanisms. β-lactam antibiotics have also been claimed to induce persistence in vitro. The present report shows that upon penicillin G (pG) treatment, inclusions grow as fast as those in infected control cells. After removal of pG, Chlamydia do not revert to RBs. These effects are independent of host cell type, serovar, biovar and species of Chlamydia. Time-course experiments demonstrated that only RBs were susceptible to pG. pG-treated bacteria lost their control over host cell apoptotic pathways and no longer expressed pre-16S rRNA, in contrast to persistent bacteria induced with adenosine/EHNA. Confocal and live-video microscopy showed that bacteria within the inclusion fused with lysosomal compartments in pG-treated cells. That leads to recruitment of cathepsin D as early as 3 h post pG treatment, an event preceding bacterial death by several hours. These data demonstrate that pG treatment of cultured cells infected with Chlamydia results in the degradation of the bacteria. In addition we show that pG is significantly more efficient than doxycycline at preventing genital inflammatory lesions in C. muridarum-C57Bl/6 infected mice. These in vivo results support the physiological relevance of our findings and their potential therapeutic applications

Climate change adaptation in agriculture; the use of multi-scale modelling and stakeholder participation in the Netherlands

Abstract about a research project to develop a methodology to assess adaptation of agriculture to climatic and socio-economic changes at multiple scales, with a first application in the Province of Flevoland, the Netherlands

Understanding Enemy Images in Central and Eastern European Politics. Towards an Interdisciplinary Approach

Europe has experienced a rise in politics based on antagonism, often discussed from the perspectives of populism and the mainstreaming of the ideologies of the radical right. In this study, we argue that there is a need for an interdisciplinary, theoretically broader and more empirically focused approach that fosters understanding of these developments. To explore the causal factors, we focus on the enemy images that are constructed and diffused by politicians, and their specific historical and structural contexts.V předchozích letech Evropa zažívá vzestup politiky založené na antagonismu, často diskutovaném v kontextu populismu a mainstreamingu ideologie radikální pravice. V tomto textu tvrdíme, že je třeba multidisciplinárního, teoreticky širšího a více empiricky zaměřeného přístupu pro porozumění tohoto vývoje. Pro zjištění kauzálních příčin se soustředíme na zobrazení nepřítele prezentované politiky a též na strukturální a specifické historické faktory