2 research outputs found
Supramolecular catalysis in the synthesis of polyfunctionalised pyrroles
<div><p>An efficient sequential one pot three component reaction involving anilines, DEAD/DMAD and glyoxal in aqueous media is reported. The protocol is environmentally benign and provides a new synthetic route to access polyfunctionalised pyrrole derivatives in high yield. The reaction proceeded via supramolecular catalysis.</p></div
Triphenylphosphine-Catalyzed, Novel, One-Pot, Multicomponent Synthesis of Functionalized β-Acetamido Carbonyls
<div><p></p><p>An efficient triphenylphosphine-catalyzed synthesis of β-acetamido carbonyls via multicomponent reaction of aromatic aldehydes, enolizable ketones or β-keto esters, acid chlorides and acetonitrile at room temperature is described. The process is remarkably simple, environmentally benign, and uses Lewis base for the first time in such type of reaction.</p>
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