Mirtazapine-Related manic / hypomanic shift: Mini review and case report

Mirtazapine-related manic / hypomanic shift: mini review and case report Mirtazapine is a pharmacological agent frequently used both as an antidepressant and as a hypnotic sedative agent. However, manic shift, an important side effect of other antidepressants, has not been adequately addressed in the treatment of mirtazapine, and the evidence has been only available from case reports. This mini-review and case report aimed to compile case reports on mirtazapine related manic shifts and to report a case where a manic shift was determined relatively early compared to that in these cases

Socio-demographic and Clinical Features of Young Adult Males Using Synthetic Cannabinoid (English)

Object: Synthetic Cannabinoid (SC) use is becoming more widespread throughout the world. Studies that revealed user profiles indicate that the drug is especially popular among young men. Knowledge on sociodemographic, clinical characteristics and motivation for SC users in our country is limited. On the other hand, in spite of the increase of information known about symptoms of acute intoxication of SC use, physical and psychiatric consequences and loss of function due to longterm use of SC is limited. In this study, we aimed to investigate socio-demographic and clinical characteristics associated with SC use and the negative consequences caused by the use of SC. Methods: 166 male patients who admitted to the psychiatric outpatient clinic due to SC use disorder between November 2014 to April 2015 were enrolled in the study. Demographic data of patients, substance use characteristics, familial substance use, reasons for substance use, medical history, the problems related to drug use was questioned. Results: The age of onset for SC use was found to be 17.25 ± 2.30. SC using duration was 3.79 ± 2.15 years. The most common agents accompanying SC use were smoking (95.8%) and cannabis (88.6%). It was determined that 62.7% developed suicidal ideas due to SC use. Among psychiatric side effects, most common were euphoria, hallucinations, skepticism and suicidal ideation. About 1/3 of cases were found to live loss of business and legal issues depending on long-term SC use. 76.5% of the patients' consumed SC through inhalation and 22.9 % orally. It was determined that oral users began SC use at an earlier age than users via inhalation. Discussion: Despite the physical, mental, occupational, social and legal problems caused by the use of SC, it has become an important public health problem, especially among young men. Effective intervention programs for the use of outbreaking SCs need to be developed

Could it be a new subtype of post-traumatic stress disorder which has cognitive impairment and psychotic symptoms ? Case report

Travma sonrası stres bozukluğu (TSSB) olgularındaki dissosiyatif belirtiler, flaşbekler ve kaçınma belirtileri sıklıkla psikotik belirtiler olarak değerlendirilebilmektedir. Son dönemdeki yayınlarda, travmaya maruz kalmış ve TSSB tanısı konan kişilerde süreçte ortaya çıkan psikotik belirtilerde özellikle dissosiyasyonun rolü ve ayrımındaki zorluklar üzerinde durulmuştur. TSSB'nun bir alt tipi olarak psikotik belirtilerle giden tipi vurgulanırken bazı olgularda görülen kognitif yıkım hala açıklanabilmiş değildir. Burada savaş travmasına maruz kalmış TSSB tanılı bir olgunun belirti ve bulguları üstünden travma, psikoz ve kognitif yıkım ilişkisi tartışılacaktırMost of the post-traumatic stress disorder (PTSD) patient who demonstrates dissociative sings, flashbacks and avoid signs could be evaluated as a psychotic disorders. In a recent research; person who exposure the traumatic event and diagnosed as a PTSD patient displays some of the psychotic features in the course of the illness. Discrimination between dissociative disorders and psychotic symptoms could be difficult. One of the subtype of the PTSD with psychotic features was mentioned, whereas the reason of the cognitive decline which seen together psychotic feauteres have not still been elicited yet. Here the association between the psychosis, trauma and cognitive impairment will be discussed over a case of PTSD symptoms and signs which have been exposed to combat- traum

Mirtazapine-related manic / hypomanic shift: mini review and case report

Mirtazapine-related manic / hypomanic shift: mini review and case report Mirtazapine is a pharmacological agent frequently used both as an antidepressant and as a hypnotic sedative agent. However, manic shift, an important side effect of other antidepressants, has not been adequately addressed in the treatment of mirtazapine, and the evidence has been only available from case reports. This mini-review and case report aimed to compile case reports on mirtazapine related manic shifts and to report a case where a manic shift was determined relatively early compared to that in these cases