High-K adakitic intrusion in the Sør Rondane Mountains, East Antarctica

The Tenth Symposium on Polar Science/Ordinary sessions: [OG] Polar Geosciences, Wed. 4 Dec. / Entrance Hall (1st floor), National Institute of Polar Researc

Smart Agriculture IoT Education Course in enPiT-everi (Education Network for Practical Information Technologies - Evolving and Empowering Regional Industries)

In Japan, expectations for the utilization of IT such as AI (Artificial Intelligence) and IoT (Internet of Things) are becoming greater and greater to address the shortage of working population due to the declining birthrate and aging population, and the depopulation of rural areas. There is a serious shortage of IT human resources, especially in rural areas, and I believe that IT human resource development is an urgent task to promote the super-smart society, Society 5.0, which is being promoted by the government. Thus, in order to promote business efficiency and productivity improvement, the utilization of IT in companies will become even more important[1]. Then, five universities, mainly in Kyushu and Chugoku regions, have been selected by the Ministry of Education, Culture, Sports, Science and Technology (MEXT) for the enPiT-Pro project, and will collaborate to provide systematic and practical IT education programs to working people from local companies, with the aim of fostering advanced IT human resources. In this paper, we report on a class of the enPIT-everi program, the Agricultural IoT Education course.The 2021 International Conference on Artificial Life and Robotics (ICAROB 2021), January 21-24, 2021, Higashi-Hiroshima (オンライン開催に変更

Geologic connection between Dronning Maud Land and Enderby Land

The Tenth Symposium on Polar Science/Ordinary sessions: [OG] Polar Geosciences, Wed. 4 Dec. / Entrance Hall (1st floor), National Institute of Polar Researc

Beneficial Effects of Cocoa in Perivascular Mato Cells of Cerebral Arterioles in SHR-SP (Izm) Rats

As previously reported, the cerebral arterioles are surrounded by unique perivascular Mato cells. They contain many inclusion bodies rich in hydrolytic enzymes, and have strong uptake capacity. They are thus considered scavenger cells of vascular and neural tissues in steady-state. In this study, employing hypertensive SHR-SP (Izm) rats, the viability of Mato cells was investigated. In hypertensive rats, the capacity for uptake of horse radish peroxidase (HRP) and the activity of acid phosphatase (ACPase) of Mato cells were markedly reduced, and on electron-microscopic examination Mato cells were found to include heterogeneous contents and appeared electron-dense and degenerated. Vascular cells exhibited some signs of pathology. However, in hypertensive rats fed chow containing 0.25% cocoa, the uptake capacity and ACPase activity of Mato cells for HRP were enhanced, and on electron-microscopic examination Mato cells appeared healthy, with mitochondria with nearly normal profiles. Signs of pathology in vascular cells were also decreased. Superoxides may impair Mato cells and vascular cells

Mineral paragenesis and its implications in the högbomite-bearing skarn, Sør Rondane Mountains, East Antarctica

第2回極域科学シンポジウム/第31回極域地学シンポジウム 11月17日（木） 国立極地研究所　2階大会議

An Analysis on the Olympus Scandal : From the Perspectives of Risk Management Theory

This thesis analyzed the Olympus Scandal which was broadly featured as a major social issue after 2011 autumn until 2012 spring. This thesis analyzed the back ground history and cause of the scandal, based on the resources opened up to the present, and drew a lesson for company risk management. This thesis especially focused on the human factor which perhaps has utmost effects to outcome of risk management

ATF6α/β-mediated adjustment of ER chaperone levels is essential for development of the notochord in medaka fish.

ATF6α and ATF6β are membrane-bound transcription factors activated by regulated intramembrane proteolysis in response to endoplasmic reticulum (ER) stress to induce various ER quality control proteins. ATF6α- and ATF6β single-knockout mice develop normally, but ATF6α/β double knockout causes embryonic lethality, the reason for which is unknown. Here we show in medaka fish that ATF6α is primarily responsible for transcriptional induction of the major ER chaperone BiP and that ATF6α/β double knockout, but not ATF6α- or ATF6β single knockout, causes embryonic lethality, as in mice. Analyses of ER stress reporters reveal that ER stress occurs physiologically during medaka early embryonic development, particularly in the brain, otic vesicle, and notochord, resulting in ATF6α- and ATF6β-mediated induction of BiP, and that knockdown of the α1 chain of type VIII collagen reduces such ER stress. The absence of transcriptional induction of several ER chaperones in ATF6α/β double knockout causes more profound ER stress and impaired notochord development, which is partially rescued by overexpression of BiP. Thus ATF6α/β-mediated adjustment of chaperone levels to increased demands in the ER is essential for development of the notochord, which synthesizes and secretes large amounts of extracellular matrix proteins to serve as the body axis before formation of the vertebra

Generation of medaka gene knockout models by target-selected mutagenesis

We have established a reverse genetics approach for the routine generation of medaka (Oryzias latipes) gene knockouts. A cryopreserved library of N-ethyl-N-nitrosourea (ENU) mutagenized fish was screened by high-throughput resequencing for induced point mutations. Nonsense and splice site mutations were retrieved for the Blm, Sirt1, Parkin and p53 genes and functional characterization of p53 mutants indicated a complete knockout of p53 function. The current cryopreserved resource is expected to contain knockouts for most medaka genes

NBRP databases: databases of biological resources in Japan

The National BioResource Project (NBRP) is a Japanese project that aims to establish a system for collecting, preserving and providing bioresources for use as experimental materials for life science research. It is promoted by 27 core resource facilities, each concerned with a particular group of organisms, and by one information center. The NBRP database is a product of this project. Thirty databases and an integrated database-retrieval system (BioResource World: BRW) have been created and made available through the NBRP home page (http://www.nbrp.jp). The 30 independent databases have individual features which directly reflect the data maintained by each resource facility. The BRW is designed for users who need to search across several resources without moving from one database to another. BRW provides access to a collection of 4.5-million records on bioresources including wild species, inbred lines, mutants, genetically engineered lines, DNA clones and so on. BRW supports summary browsing, keyword searching, and searching by DNA sequences or gene ontology. The results of searches provide links to online requests for distribution of research materials. A circulation system allows users to submit details of papers published on research conducted using NBRP resources

ヒガシ ドロンイングモードランド, セール・ロンダーネ サンチ チガク チョウサタイ ホウコク 2008-2009 (JARE-50)

第50次日本南極地域観測隊(JARE-50)夏隊・セール・ロンダーネ山地地学調査隊は,山地西部地域の地質調査を実施した(国立極地研究所一般研究プロジェクト,P-5-1:代表・本吉洋一).調査地へは,ドロンイングモードランド航空ネットワークを利用して空路ケープタウンから山地に入った.メンバーの構成は,地質調査担当5名とフィールドアシスタント1名である.調査地では三つのキャンプ(ベースキャンプ,前進キャンプ1および前進キャンプ2)を設営し,75日間すべてテントで生活した.本報告では,セール・ロンダーネ山地地学調査隊の設営,西部の気象条件および野外調査結果を含め,調査計画から実施に至る過程について記述する.The Sør Rondane Mountains field party, part of the summer party of the 50th Japanese Antarctic Research Expedition (JARE-50), consisted of five geologists and one field assistant, and conducted geological fieldwork in the western Sr Rondane Mountains, Eastern Dronning Maud Land, as part of a research project of the National Institute of Polar Research (#P-5-1). The field party accessed the mountains using the Dronning Maud Land Air Network (DROMLAN) from Cape Town to a runway close to the Belgian base, via the Novolazarevskaya runway. The field party made three campsites (Base Camp, Camp 1, and Camp 3) and stayed on the snowfield for 75 days. Here, we report the detailed operation plans and present a summary of the fieldwork, including information on logistics and weather reports for the western Sør Rondane Mountains