Estimates of combining ability and standard heterosis for grain yield and various agromorphological traits in rice (Oryza sativa L.)

A study was conducted for estimating combining ability and standard heterosis for grain yield and various agromorphological traits involving 10 parents and their 45 F1s (half diallel) during 2012-13 and 2013-14. The results of present investigation revealed that additive gene action played a predominant role in the inheritance of most of the traits under study. On the basis of general combining ability (GCA) effects and specific combining ability (SCA) effects, three parents (Vallabh Basmati 21, Pusa Basmati 1, CSR 13) and three crosses (Vallabh Basmati 21 x Pusa 1121, Pusa 1121 x CSR 13 and Pusa Basmati 1 x CSR 13) were found good general and specific combiners. The best combinations mostly involved good x good and good x poor parental GCA effects suggesting that there is addi-tive x additive and additive x dominance type of gene action for yield and other component traits. The cross showing additive gene action can be improved by pedigree breeding and selection can be postponed to later generations. The most appropriate breeding method for the exploitation of non additive gene action will be heterosis breeding. The six best cross combinations (Vallabh Basmati 21 x CSR 30, CSR 30 x CSR 13, Vallabh Basmati 21 x CSR 13, CSR 30 x Pusa basmati 1, Pusa basmati 1 x CSR 13 and Vallabh Basmati 21 x Pusa basmati 1) had significant standard heterosis for grain yield and other component traits. The crosses which showed significant standard heter-osis is highly suitable for commercial exploitation of heterosis in rice crop

Estimates of genetic parameters for grain yield, various yield components and some quality traits in rice (Oryza sativa L.)

A study was conducted during two crop season (Kharif, 2011-12 and 2012-13) for estimating the genetic parameters by involving 10 parents and their 45 F1s in rice crop. The estimates of h2 (overall dominance effects) were positive and significant for days to 50 % flowering (9.11), days to maturity (0.24), plant height (2.95), panicle length1(39), productive tillers per plant (3.22), branches per panicle (5.61), flag leaf area (5.50), 1000-grain weight (0.27), biological yield (7.35) and amylose content (1.03) which indicated dominance of genetic components in F1s crosses. The theoretical value (0.25) of (H2/4H1) for all the traits except kernel length and amylose content indicated the asymmetrical distribution of positive and negative genes in the parents. The proportion of dominant and recessive alleles for panicle length, productive tillers, branches per panicle, 1000 grain weight, biological yield, kernel length and L/B ratio reflected more dominant alleles, whereas for days to 50 % flowering, days to maturity, plant height, grains per panicle, flag leaf area, grain yield, harvest index, kernel breadth, kernel length after cooking, elongation ratio, amylose content and hulling %, reflected more recessive alleles in the parents. The estimates of specific combining ability (SCA) effects revealed that the cross Vallabh Basmati 21 x Pusa 1121 could be an excellent candidate for improving grain yield (1.52**), harvest index (1.86**) and flag leaf area (6.20**) whereas Pusa 1121 x CSR 10 is excellent candidate for panicle length (0.89**) and amylose content (1.54**). The characters showing more than 60 % narrow sense heritability along with positive and significant correlation with each other and also with grain yield could be rewarding for further improvement of yield and quality in rice. Therefore, these parental lines can be used as donors in future by following bi-parental mating and the diallel selective mating system could be the best breeding method in an early segregating generation for improvement in these traits in rice crop

Discovery of highly spin-polarized conducting surface states in the strong spin-orbit coupling semiconductor Sb2_2Se3_3

Majority of the A$_2$B$_3$ type chalcogenide systems with strong spin-orbit coupling, like Bi$_2$Se$_3$, Bi$_2$Te$_3$ and Sb$_2$Te$_3$ etc., are topological insulators. One important exception is Sb$_2$Se$_3$, where a topological non-trivial phase was argued to be possible under ambient conditions, but such a phase could be detected to exist only under pressure. In this Letter, we show that like Bi$_2$Se$_3$, Sb$_2$Se$_3$, displays generation of highly spin-polarized current under mesoscopic superconducting point contacts as measured by point contact Andreev reflection spectroscopy. In addition, we observe a large negative and anisotropic magnetoresistance in Sb$_2$Se$_3$, when the field is rotated in the basal plane. However, unlike in Bi$_2$Se$_3$, in case of Sb$_2$Se$_3$ a prominent quasiparticle interference (QPI) pattern around the defects could be obtained in STM conductance imaging. Thus, our experiments indicate that Sb$_2$Se$_3$ is a regular band insulator under ambient conditions, but due to it's high spin-orbit coupling, non-trivial spin-texture exists on the surface and the system could be on the verge of a topological insulator phase.Comment: 5 pages, 4 figures, supplemental material not include

Identification of heterotic cross combinations for various agromorphological and some quality traits in bread wheat (Triticum aestivum L.)

A study was conducted to identify the best heterotic cross for various agromorphological and some quality traits involving 10 parents and their 45 F1s excluding reciprocals during 2012-13 and 2013-14. The higher magnitude of heterosis for all the agromorphological and quality traits was not expressed in a single cross combination. It varied from cross to cross due to diverse genetic background of their parents. The highest heterobeltiosis (35.68%, 11.11%, 11.44%), average heterosis (38.97%, 9.13%, 10.26%) and standard heterosis (31.09%, 7.84%, 10.41%) for grain yield, spikelets per spike and grains per spike respectively, was showed by HD 3095 x RAJ 4246 and this cross also showed highly significant (at <1% level of significant) heterosis for biological yield, flag leaf area, spike length and productive tillers. Whereas PBW 435 x RAJ 4246 were common for gluten content (8.52% and 7.72%), grain yield (33.11% and 33.64%), productive tillers (16.15% and 13.53%) and biological yield (36.27% and 21.98%) which showed superior average heterosis and heterobeltiosis respectively, therefore, these crosses may be exploit-ed in a national hybrid wheat breeding programme may offer genetic improvement in breeding for higher grain yield, agromorphological and quality traits in bread wheat. The presence of high heterosis for yield contributing compo-nents is not only for developing hybrids through exploitation of heterosis but also helps to produce transgressive segregants for developing of superior homozygous lines

Radial club hand managed with ulnar osteotomy and centralization of hand: a case report and review

Radial club hand also called radial longitudinal deficiency or radial dyspasia is a preaxial longitudinal failure of formation. As the defect is preaxial it is often associated with thumb hypoplasia or anomaly of the radial aspect of the carpus. It is diagnosed clinically and on X-rays. It is frequently syndromic so it is a must to look for associated congenital anomalies by doing a through clinical examination. The frequency of this anomaly is between 1:50000 to 1:100000 live births. The incidence of all radial ray-deficient limbs, including hypoplastic thumbs alone, is approximately 1:30000. The radial deficiency is bilateral in 50% of the cases and the male:female is 3:2. It includes a wide spectrum of disorders that encompass an absent thumb or thumb hypoplasia, a thin first metacarpal and an absent radius. We report here a 1.5 years old child with isolated type IV radial club hand without any restricted range of motion in elbow managed with osteotomy of ulna and centralization of hand

Tribological behavior and biocompatibility of novel Nickel-Free stainless steel manufactured via laser powder bed fusion for biomedical applications

Due to the risk of releasing carcinogenic nickel ions from conventional 316L stainless steel under a corrosive human body environment, a new variant of steel termed nickel-free stainless steel (NiFSS) has been investigated. The present study investigates the tribological properties and biocompatibility of NiFSS manufactured via laser powder bed fusion (PBF-LB/M). The ferritic NiFSS exhibited significantly lower coefficient of friction (0.08 to 0.28) and wear rate (1.60 × 10-6 mm3/Nm to 6.60 × 10-6 mm3/Nm) compared to reported values for austenitic 316L SS, under both dry and simulated body fluid (SBF) conditions and various sliding geometries. This improvement is attributed to the superior hardness (3.394 ± 0.1340 GPa) and elastic modulus (238 ± 9.0797 GPa) of NiFSS. To assess the biocompatibility, the viability of mouse pre-osteoblastic MC3T3-E1 cells was evaluated with an Alamar Blue assay when the cells were cultured on top of PBF-LB/M built NiFSS and 316L SS samples. The results indicated that even though cell growth was most optimal on regular cell culture plastic, cell viability was better maintained on PBF-LB/M built NiFSS compared to 316L SS. Therefore, the results of the present study propose that PBF-LB/M fabricated NiFSS holds promise for application in biomedical devices for joint arthroplasty.Peer reviewe

Cytoprotective effect of methanolic extract of Nardostachys jatamansi against hydrogen peroxide induced oxidative damage in C6 glioma cells

Oxidative stress has been implicated as an important factor in the process of neurodegeneration and hydrogen peroxide (H2O2) is one of the most important precursors of reactive oxygen species (ROS), responsible for many neurodegenerative diseases. This study used extracts from Nardostachys jatamansi rhizomes, known for nerve relaxing properties in Ayurvedic medicine, to ascertain their protective role in H2O2-induced oxidative stress in C6 glioma cells. The protective effect of methanolic, ethanolic and water extracts of N. jatamansi (NJ-MEx, NJ-EEx and NJ-WEx respectively) was determined by MTT assay. NJ-MEx significantly protected against H2O2 cytotoxicity when cells were pretreated for 24 h. The level of antioxidant enzymes, catalase, superoxide dismutase (Cu-ZnSOD), glutathione peroxidase (GPx), and a direct scavenger of free radicals, glutathione (GSH), significantly increased following pre-treatment with NJ-MEx. Lipid peroxidation (LPx) significantly decreased in NJ-MEx-pretreated cultures. The expression of a C6 differentiation marker, GFAP (glial fibrillary acidic protein), stress markers HSP70 (heat shock protein) and mortalin (also called glucose regulated protein 75, Grp75) significantly decreased when cells were pre-treated with NJ-MEx before being subjected to H2O2 treatment as shown by immunofluorescence, western blotting and RT-PCR results. The present study suggests that NJ-MEx could serve as a potential treatment and/or preventive measure against neurodegenerative diseases

“COVID- 19 Vaccination utilization pattern of the beneficiaries attending COVID 19 vaccination centre at a Medical college in Haryana, India”

Introduction: The COVID vaccination was introduced this year and there was lot of hesitancy amongst the people including health care workers. The pace of COVID vaccination increased with each passing day. No previous data was available about the utilization pattern of beneficiaries of COVID vaccination. Objective : This study was conducted to know the vaccine utilization pattern amongst general population as well as health care workers at a tertiary care health institute.Method: The beneficiaries who received COVID vaccination from 16th January 2021 to 15th June 2021 at a COVID Vaccination Centre of a tertiary care health institute in Haryana ( n= (Total = 9721).Result : Total number of beneficiaries vaccinated with 1st dose during the study period were 9721. Out of total vaccinated, 1600 (16.45%) were health care workers. Coverage of vaccination with first dose was maximum in the administrative staff (Data Entry Operators /Clerk/IT/other managers, Receptionist, Technical Staff etc) was 100 % and minimum in doctors ( 66.4 %) .Conclusion: Vaccine coverage in HCW with first dose in the study hospital was 82.27 % and for 2nd dose was 64.35% which is comparatively less to first dose. More sensitization of HCW is required to motivate them for second dose of Covid vaccination