Studies on the biosynthesis of cordycepin

The carboxyl carbons of acetate and isovalerate do not serve to any appreciable extent as precursors of cordycepin, thus arguing against the origin of cordycepose from pathways of isoprenoid biosynthesis. Exogenously added [8-14C]adenine, [I-14C]-glucose, and [6-14C]glucose serve as excellent precursors, the latter two compounds labeling both the base and sugar of the nucleoside. [6-14C]glucose labels cordycepose better than [I-14C]glucose, thereby indicating a loss of carbon atom number one of the glucose molecule in cordycepose synthesis.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/32376/1/0000451.pd

Hydrolysis of nucleoside di- and triphosphates by crystalline preparations of yeast inorganic pyrophosphatase

1. 1. Crystalline preparations of yeast inorganic pyrophosphatase catalyze phosphate liberation from ATP and ADP, as well as from pyrophosphate, in the presence of zinc ions.2. 2. A variety of other nucleoside di- and triphosphates are hydrolyzed in the presence of zinc ions and pyrophosphatase, and manganous and cobaltous ions can partially substitute for zinc in effecting ATP hydrolysis.3. 3. Although several lines of evidence suggest that a single protein possesses Mg++-pyrophosphatase and Zn++-ATPase activities, the possibility cannot be eliminated that a different protein, present in small amounts, accounts for the ATPase activity.4. 4. Evidence has been obtained that the hydrolysis of ATP occurs primarily between the [beta]- and [gamma]-phosphate groups to yield ADP, which is then converted to AMP.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/32415/1/0000492.pd

l-Threonine Deaminase of Rhodospirillum rubrum

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65547/1/j.1432-1033.1971.tb01490.x.pd

Tight binding inhibitors of xanthine oxidase

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/24536/1/0000815.pd

Neutron-induced nucleosynthesis

Neutron--induced nucleosynthesis plays an important role in astrophysical scenarios like in primordial nucleosynthesis in the early universe, in the s--process occurring in Red Giants, and in the $\alpha$--rich freeze--out and r--process taking place in supernovae of type II. A review of the three important aspects of neutron--induced nucleosynthesis is given: astrophysical background, experimental methods and theoretical models for determining reaction cross sections and reaction rates at thermonuclear energies. Three specific examples of neutron capture at thermal and thermonuclear energies are discussed in some detail.Comment: 40 pages (uses kluwer.sty), 2 postscript figures (uses psfig), accepted for publication in Surveys in Geophysics, uuencoded tex-files and postscript-files available at ftp://is1.kph.tuwien.ac.at/pub/ohu/Geo.u