38 research outputs found
High-resolution bathymetries and shorelines for the Great Lakes of the White Nile basin
This article is licensed under a Creative Commons Attribution 4.0 International License.HRBS-GLWNB 2020 presents the first open-source and high-resolution bathymetry, shoreline, and water level data for Lakes Victoria, Albert, Edward, and George in East Africa. For each Lake, these data have three primary products collected for this project. The bathymetric datasets were created from approximately 18 million acoustic soundings. Over 8,200 km of shorelines are delineated across the three lakes from high-resolution satellite systems and uncrewed aerial vehicles. Finally, these data are tied together by creating lake surface elevation models collected from GPS and altimeter measures. The data repository includes additional derived products, including surface areas, water volumes, shoreline lengths, lake elevation levels, and geodetic information. These data can be used to make allocation decisions regarding the freshwater resources within Africa, manage food resources on which many tens of millions of people rely, and help preserve the region’s endemic biodiversity. Finally, as these data are tied to globally consistent geodetic models, they can be used in future global and regional climate change models.ECU Open Access Publishing Support Fun
Metabolic Syndrome and Cardiovascular Disease after Hematopoietic Cell Transplantation: Screening and Preventive Practice Recommendations from the CIBMTR and EBMT
Metabolic syndrome (MetS) is a constellation of cardiovascular risk factors that increases the risk of cardiovascular disease, diabetes mellitus, and all-cause mortality. Long-term survivors of hematopoietic cell transplantation (HCT) have a substantial risk of developing MetS and cardiovascular disease, with an estimated prevalence of MetS of 31% to 49% among HCT recipients. Although MetS has not yet been proven to impact cardiovascular risk after HCT, an understanding of the incidence and risk factors for MetS in HCT recipients can provide the foundation to evaluate screening guidelines and develop interventions that may mitigate cardiovascular-related mortality. A working group was established through the Center for International Blood and Marrow Transplant Research and the European Group for Blood and Marrow Transplantation with the goal to review literature and recommend practices appropriate to HCT recipients. Here we deliver consensus recommendations to help clinicians provide screening and preventive care for MetS and cardiovascular disease among HCT recipients. All HCT survivors should be advised of the risks of MetS and encouraged to undergo recommended screening based on their predisposition and ongoing risk factors
Response of fish stocks in Lake Victoria to enforcement of the ban on illegal fishing:are there lessons for management?
Most small-scale inland fisheries in the Global South prohibit fishing gear with smaller meshes than is legally permitted. Nonetheless, in most instances, this is not strictly enforced. But starting in 2017, Uganda and Tanzania ramped up enforcement on Lake Victoria. We used time series hydro-acoustic data to determine whether the strict enforcement achieved the management goal of increased biomass (t) of commercial species and an increase in the biomass of big Nile perch (>50 cm). The biomass for 2018–2021 (under strict enforcement) was expected to be greater than in 2007–2017 (prior to strict enforcement). The biomass of key species fluctuated annually, but no spatial or temporal differences in biomass associated with strict enforcement were evident. Similarly, the biomass of big Nile perch did not increase. Our findings suggest that mesh sizes may have limited influence on fish biomass dynamics in Lake Victoria, and that high primary productivity of the lake, high turnover rates of fish species, and limited compliance by fishers likely counteract the effects of high fishing effort on biomass and size structure of fish. Therefore, the high cost of strict top-down enforcement and the societal cost of lost lives, jobs, and livelihoods may not be justified
Modeling combination therapy for breast cancer with BET and immune checkpoint inhibitors
A Case of Primary Bone Marrow B-Cell Non Hodgkin’s Lymphoma with Severe Thrombocytopenia: Case Report and A Review of the Literature
A 78-year-old man presented with persistent gingival bleeding. He had low platelet count of 1.0 × 109/L without any lymphadenopathy. Bone marrow specimen showed diffusely distributed small-sized lymphocytes. Combined with immunophenotypic analysis, a diagnosis of primary bone marrow B-cell non-Hodgkin’s lymphoma was made. Thrombocytopenia was considered to be caused by autoimmune destruction of platelets