258 research outputs found
Method for deducing anisotropic spin-exchange rates
Using measured spin-transfer rates from alkali atoms to He-3, combined with
spin-relaxation rates of the alkali atoms due to He-3 and He-4, it should be
possible to differentiate between isotropic and anisotropic spin-exchange. This
would give a fundamental limit on the He-3 polarization attainable in
spin-exchange optical pumping. For K-He, we find the limit to be 0.90+-0.11
The Effect of \u3ci\u3eLucas v. South Carolina Coastal Council\u3c/i\u3e on the Law of Regulatory Takings
In Lucas v. South Carolina Coastal Council, the United States Supreme Court established a two-part takings analysis. The first step is an economically viable use threshold question, subject to a nuisance exception. The second step is a balancing test in which courts weigh the public and private interests involved. Although this two-part analysis differs in structure from most lower court takings analyses, most courts already apply a functionally equivalent test. Therefore, unless the Court alters the unit of land to which it applies, this new analysis will have little effect on the outcome of takings challenges to land use regulations
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Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes.
Recently, a severe combined immunodeficiency syndrome with a deficiency of CD8+ peripheral T cells and a TCR signal transduction defect in peripheral CD4+ T cells was associated with mutations in ZAP-70. Since TCR signaling is required in developmental decisions resulting in mature CD4 (and CD8) T cells, the presence of peripheral CD4+ T cells expressing TCRs incapable of signaling in these patients is paradoxical. Here, we show that the TCRs on thymocytes, but not peripheral T cells, from a ZAP-70-deficient patient are capable of signaling. Moreover, the TCR on a thymocyte line derived from this patient can signal, and the homologous kinase Syk is present at high levels and is tyrosine phosphorylated after TCR stimulation. Thus, Syk may compensate for the loss of ZAP-70 and account for the thymic selection of at least a subset of T cells (CD4+) in ZAP-70-deficient patients
Checking-in to Create Instructor-Student Immediacy in Honors
Weekly, self-evaluative briefs are used to assess students’ general wellbeing during the coronavirus crisis. Authors discuss the efficacy of personalized check-ins and remote, interpersonal rapport, suggesting a positive impact on student learning outcomes
Non-destructive spatial heterodyne imaging of cold atoms
We demonstrate a new method for non-destructive imaging of laser-cooled
atoms. This spatial heterodyne technique forms a phase image by interfering a
strong carrier laser beam with a weak probe beam that passes through the cold
atom cloud. The figure of merit equals or exceeds that of phase-contrast
imaging, and the technique can be used over a wider range of spatial scales. We
show images of a dark spot MOT taken with imaging fluences as low as 61 pJ/cm^2
at a detuning of 11 linewidths, resulting in 0.0004 photons scattered per atom.Comment: text+3 figures, submitted to Optics Letter
Spin-axis relaxation in spin-exchange collisions of alkali atoms
We present calculations of spin-relaxation rates of alkali-metal atoms due to
the spin-axis interaction acting in binary collisions between the atoms. We
show that for the high-temperature conditions of interest here, the spin
relaxation rates calculated with classical-path trajectories are nearly the
same as those calculated with the distorted-wave Born approximation. We compare
these calculations to recent experiments that used magnetic decoupling to
isolate spin relaxation due to binary collisions from that due to the formation
of triplet van-der-Waals molecules. The values of the spin-axis coupling
coefficients deduced from measurements of binary collision rates are consistent
with those deduced from molecular decoupling experiments. All the experimental
data is consistent with a simple and physically plausible scaling law for the
spin-axis coupling coefficients.Comment: text+1 figur
Reconstitution of T cell receptor signaling in ZAP-70-deficient cells by retroviral transduction of the ZAP-70 gene.
A variant of severe combined immunodeficiency syndrome (SCID) with a selective inability to produce CD8 single positive T cells and a signal transduction defect in peripheral CD4+ cells has recently been shown to be the result of mutations in the ZAP-70 gene. T cell receptor (TCR) signaling requires the association of the ZAP-70 protein tyrosine kinase with the TCR complex. Human T cell leukemia virus type I-transformed CD4+ T cell lines were established from ZAP-70-deficient patients and normal controls. ZAP-70 was expressed and appropriately phosphorylated in normal T cell lines after TCR engagement, but was not detected in T cell lines from ZAP-70-deficient patients. To determine whether signaling could be reconstituted, wild-type ZAP-70 was introduced into deficient cells with a ZAP-70 retroviral vector. High titer producer clones expressing ZAP-70 were generated in the Gibbon ape leukemia virus packaging line PG13. After transduction, ZAP-70 was detected at levels equivalent to those observed in normal cells, and was appropriately phosphorylated on tyrosine after receptor engagement. The kinase activity of ZAP-70 in the reconstituted cells was also appropriately upregulated by receptor aggregation. Moreover, normal and transduced cells, but not ZAP-70-deficient cells, were able to mobilize calcium after receptor ligation, indicating that proximal TCR signaling was reconstituted. These results indicate that this form of SCID may be corrected by gene therapy
Spin Relaxation Resonances Due to the Spin-Axis Interaction in Dense Rubidium and Cesium Vapor
Resonances in the magnetic decoupling curves for the spin relaxation of dense
alkali-metal vapors prove that much of the relaxation is due to the spin-axis
interaction in triplet dimers. Initial estimates of the spin-axis coupling
coefficients for the dimers are 290 MHz for Rb; 2500 MHz for Cs.Comment: submitted to Physical Review Letters, text + 3 figure
Measurement-induced Squeezing of a Bose-Einstein Condensate
We discuss the dynamics of a Bose-Einstein condensate during its
nondestructive imaging. A generalized Lindblad superoperator in the condensate
master equation is used to include the effect of the measurement. A continuous
imaging with a sufficiently high laser intensity progressively drives the
quantum state of the condensate into number squeezed states. Observable
consequences of such a measurement-induced squeezing are discussed.Comment: 4 pages, 2 figures, submitted to PR
Detecting Neutral Atoms on an Atom Chip
Detecting single atoms (qubits) is a key requirement for implementing quantum
information processing on an atom chip. The detector should ideally be
integrated on the chip. Here we present and compare different methods capable
of detecting neutral atoms on an atom chip. After a short introduction to
fluorescence and absorption detection we discuss cavity enhanced detection of
single atoms. In particular we concentrate on optical fiber based detectors
such as fiber cavities and tapered fiber dipole traps. We discuss the various
constraints in building such detectors in detail along with the current
implementations on atom chips. Results from experimental tests of fiber
integration are also described. In addition we present a pilot experiment for
atom detection using a concentric cavity to verify the required scaling.Comment: 13 pages, 12 figure
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