An Ethnobotanical Survey of Herbal Markets and Medicinal Plants in Lagos State of Nigeria

An ethnobotanical survey of three largest herbal markets and medicinal plants used for treating ailments in Lagos state of Nigeria was undertaken by means of oral and written questionnaire. Traditional medicine is undoubtedly a reliable alternative approach to health care delivery in the metropolis because it is cheap, easily accessible, and efficacious. Herbs are obtained from bushes around the neighbourhood and forests from adjacent states. Recipes for the treatment of common ailments which are reported almost on daily basis such as hypertension, dysentery, low sperm count and weak erection, coated tongue, pile, menstrual disorder, leucorrhoea and fevers were given by the practitioners. Moreover, a list of medicinal plants and their reported folkloric uses was compiled during the survey. Apparently, daily health issues of Lagosians are partly taken care of by traditional medicine and its use is on the increase in Lagos state. The efforts of the Lagos State Traditional Medicine Board and Nigeria Natural Medicine Development Agency are praised in facilitating recognition of herbal medicine in the metropolis. Government should help in the area of conservation of medicinal plant and protect patent right of the Traditional Medicine Practitioners to encourage release of information

Systematic significance of the leaf cuticle of Hypodaphnis zenkeri (Engl.) Stapf (Lauraceae) and a record of its volatile organic compounds

Hypodaphnis zenkeri is a monotypic taxon whose position is basal in the phylogenetic tree of the family Lauraceae. Cuticular information on the plant is lacking. Given the systematic relevance of this character in the family and absence of its record for the species, the leaves of the species were investigated with the aid of light and scanning electron microscopy. Also, volatile organic compounds in leaves and fruits were studied with Gas Chromatography-Mass Spectrometry (GC-MS), for the first time. Taxonomically useful cuticular features of the species include long stomatal rim and aperture, granulated periclinal walls on the adaxial surface and superficial stomatal orientation. The leaves and fruits of the plant are rich in volatile organic compounds such as 1,2-benzene-dicarboxylic acid, hexadecanoic acid ester and stigmasta-3,5-diene. Based on these features, the species can be distinguished from other related taxa in the family

Report of the International Society of Hypertension (ISH) Hypertension Teaching Seminar organized by the ISH Africa Regional Advisory Group: Maputo, Mozambique, 2016

The International Society of Hypertension (ISH), in fulfilment of its mission of promoting hypertension control and prevention and also of advancing knowledge globally, organizes hypertension teaching seminars or ‘summer schools’ worldwide through the ISH Regional Advisory Groups. In Africa, seven of such seminars have been organized. This is a report of the eighth seminar held in Maputo, Mozambique, April, 2016. The seminar was attended by over 65 participants from 11 African countries. The Faculty consisted of 11 international hypertension experts. The eighth African hypertension seminar was a great success as confirmed by a pre- and post-test questionnaire

Protocol for a feasibility study of smoking cessation in the surgical pathway before major lung surgery: Project MURRAY

INTRODUCTION: Smoking prior to major thoracic surgery is the biggest risk factor for development of postoperative pulmonary complications, with one in five patients continuing to smoke before surgery. Current guidance is that all patients should stop smoking before elective surgery yet very few are offered specialist smoking cessation support. Patients would prefer support within the thoracic surgical pathway. No study has addressed the effectiveness of such an intervention in this setting on cessation. The overall aim is to determine in patients who undergo major elective thoracic surgery whether an intervention integrated (INT) into the surgical pathway improves smoking cessation rates compared with usual care (UC) of standard community/hospital based NHS smoking support. This pilot study will evaluate feasibility of a substantive trial. METHODS AND ANALYSIS: Project MURRAY is a trial comparing the effectiveness of INT and UC on smoking cessation. INT is pharmacotherapy and a hybrid of behavioural support delivered by the trained healthcare practitioners (HCPs) in the thoracic surgical pathway and a complimentary web-based application. This pilot study will evaluate the feasibility of a substantive trial and study processes in five adult thoracic centres including the University Hospitals Birmingham NHS Foundation Trust. The primary objective is to establish the proportion of those eligible who agree to participate. Secondary objectives include evaluation of study processes. Analyses of feasibility and patient-reported outcomes will take the form of simple descriptive statistics and where appropriate, point estimates of effects sizes and associated 95% CIs. ETHICS AND DISSEMINATION: The study has obtained ethical approval from NHS Research Ethics Committee (REC number 19/WM/0097). Dissemination plan includes informing patients and HCPs; engaging multidisciplinary professionals to support a proposal of a definitive trial and submission for a full application dependent on the success of the study. TRIAL REGISTRATION NUMBER: NCT04190966

Diagnostic challenge for ovarian malignant melanoma in premenopausal women: Primary or metastatic?

<p>Abstract</p> <p>Background</p> <p>In the ovary, metastatic malignant melanoma may be confused with primary malignant melanoma and presents a diagnosis challenge. Most cases are associated with disseminated diseases and poor prognosis. We present this case report of a metastatic ovarian malignant melanoma simulating primary ovarian cancer.</p> <p>Case report</p> <p>A 45-year-old premenopausal woman was incidentally found to have an abdominal mass, 3 years after removal of a cutaneous melanoma lesion. Ultrasound and CT scan revealed left two solid masses, which were found to be an ovarian tumor at laparotomy. Left oophorectomy was performed. Histopathology and immunohistochemistry showed melanoma metastasis to the ovary. Nine months later, the patient developed epilepsy and confusion. Magnetic Resonance Imaging showed unique Wright frontal lobe lesion. She underwent stereotactic radio surgery and dacarbazine monotherapy. For months later, the patient is died from disseminate disease progression.</p> <p>Conclusion</p> <p>Ovarian metastasis is an unusual presentation of cutaneous melanoma and the prognosis was dismal. As illustrated by this case report, a differential diagnosis of a metastatic malignant melanoma must be considered.</p