Aspergillus fumigatus related pacemaker infection

İmplante edilmiş kalp pili (KP) sisteminde fungal enfeksiyonlar çok nadir görülen ve ölümcül olan bir komplikasyondur. Tanı konulduğunda cihaz tamamen çıkarılmalı, uzun süreli antifungal tedavi başlanmalıdır. Burada 52 yaşında Aspergillus fumigatus’a bağlı KP infeksiyonu gelişen hastayı sunacağız.Fungal infections are rare but potentially lethal complication of pacemaker system. The infected implantable device must be completely removed and prolonged antifungal therapy is required. Here we reported our experience with Aspergillus fumigatus related pacemaker lead infection in a 52 years old patient

Fever of Unknown Origin: Report of 62 Cases

Fever of unknown origin is defined as fever above 38.3°C in several episodes in 3 weeks period, in the absence of specific diagnosis established by the end of 1 week inpatient evaluation. Sixtytwo patients, fitting the criteria of fever of unknown origin, followed in our clinics between 1993-1997 were investigated retrospectively. Minor or major invasive procedures were applied to 46 (74%) (7 laparotomies) patients. A specific diagnosis has been established in 55 (89%) patients. Infections, connective tissue diseases, neoplasms and other diseases were diagnosed in 31(50%), 13 (21%), 7 (11%) and 4 (6%) cases respectively. Among all, infections were the leading cause. When the infections were considered; tuberculosis (12 cases 19%) was the first in rank followed by endocarditis (7 cases 11%). Disseminated tuberculosis was the most frequent tuberculosis form. Still’s disease (5, 8%) and lymphomas were the leading forms of connective tissue diseases and neoplasms respectively. No diagnosis has been established in 7 (11%) out of 62 patients. Laparatomy had direct contribution to diagnosis in 6 cases making the diagnostic value of the procedure 86%. In the circumstances of our country, infections are the leading cause of fever of unknown origin and beyond tuberculosis; endocarditis and brucellosis should be beard in mind

Infective Endocarditis cases with the Clinical Presentation of Fever of Unknown Origin (FUO): 7 Case Reports

Fever of unknown origin (FUO) is described as documented fevers above 38.3°C, for more than three weeks of duration and lack of a specific diagnosis after one week of investigation. The most common causes of FUO in adult patients are infections, neoplasms and collagen vascular diseases. In adults, the most common causes of FUO are infections. Also in our country, more than half of the reported cases are caused by infections. Infective endocarditis is reported as the cause of 0-8% of FUO cases in developed countries, and 0-3.8% in our country. In this study, we established the diagnosis of infective endocarditis in 11.2% (7 patients) of 62 FUO patients. We discussed the diagnostic difficulties, probable predisposing factors, clinical and laboratory findings of infective endocarditis and the role of infective endocarditis in FUO cases in our cauntry by reviewing these seven patients with infective endocarditis

Diabetic Extremity Infections: Our Clinical Experiences

Between April’93 & March’96, we follewed 93 patients (68 men & 33 women) who have 101 extremity infections in Internal Medicine Section, Infectious Diseases Unit. Among them one patient three times and six patients two times was followed. 93 infections diagnosed in lower extremities and 8 in upper. 39 (38.6%) of them was osteomyelitis and 62 (61.4%) wus soft tissue infection. Amputation was done in 17 (16.8%) patients because of late admission and gangrene 28 (27.7%) bacterial growth detected in aspiration cultures. The most frequent isolate was S.aureus (35.6%)