8 research outputs found
Implementation Of Anonymous Vehicle Reporting And Communication System For Wrongly Parked Vehicle
Improper parking can cause several issues and problems, including Reduced Accessibility, Inconvenience for Other Drivers, Public Transportation Disruption, Environmental and Aesthetic Concerns, Public Perception, and Traffic Congestion.
Addressing these issues typically calls for a combination of traffic management, public awareness campaigns, law enforcement, smart urban design, and community involvement to preserve the successful and safe usage of public spaces
COVID-19 trajectories among 57 million adults in England: a cohort study using electronic health records
BACKGROUND:
Updatable estimates of COVID-19 onset, progression, and trajectories underpin pandemic mitigation efforts. To identify and characterise disease trajectories, we aimed to define and validate ten COVID-19 phenotypes from nationwide linked electronic health records (EHR) using an extensible framework.
METHODS:
In this cohort study, we used eight linked National Health Service (NHS) datasets for people in England alive on Jan 23, 2020. Data on COVID-19 testing, vaccination, primary and secondary care records, and death registrations were collected until Nov 30, 2021. We defined ten COVID-19 phenotypes reflecting clinically relevant stages of disease severity and encompassing five categories: positive SARS-CoV-2 test, primary care diagnosis, hospital admission, ventilation modality (four phenotypes), and death (three phenotypes). We constructed patient trajectories illustrating transition frequency and duration between phenotypes. Analyses were stratified by pandemic waves and vaccination status.
FINDINGS:
Among 57 032 174 individuals included in the cohort, 13 990 423 COVID-19 events were identified in 7 244 925 individuals, equating to an infection rate of 12·7% during the study period. Of 7 244 925 individuals, 460 737 (6·4%) were admitted to hospital and 158 020 (2·2%) died. Of 460 737 individuals who were admitted to hospital, 48 847 (10·6%) were admitted to the intensive care unit (ICU), 69 090 (15·0%) received non-invasive ventilation, and 25 928 (5·6%) received invasive ventilation. Among 384 135 patients who were admitted to hospital but did not require ventilation, mortality was higher in wave 1 (23 485 [30·4%] of 77 202 patients) than wave 2 (44 220 [23·1%] of 191 528 patients), but remained unchanged for patients admitted to the ICU. Mortality was highest among patients who received ventilatory support outside of the ICU in wave 1 (2569 [50·7%] of 5063 patients). 15 486 (9·8%) of 158 020 COVID-19-related deaths occurred within 28 days of the first COVID-19 event without a COVID-19 diagnoses on the death certificate. 10 884 (6·9%) of 158 020 deaths were identified exclusively from mortality data with no previous COVID-19 phenotype recorded. We observed longer patient trajectories in wave 2 than wave 1.
INTERPRETATION:
Our analyses illustrate the wide spectrum of disease trajectories as shown by differences in incidence, survival, and clinical pathways. We have provided a modular analytical framework that can be used to monitor the impact of the pandemic and generate evidence of clinical and policy relevance using multiple EHR sources.
FUNDING:
British Heart Foundation Data Science Centre, led by Health Data Research UK
Effect of Bombay high crude oil and its water-soluble fraction on growth and metabolism of diatom Thalassiosira sp.
251-255Effect of Bombay high crude oil (BHC) and its water-soluble fraction (WSF) on growth and metabolism of the phytoplankton, Thalassiosira sp. was assessed. The study revealed the signs of acute toxicity at higher concentrations of crude oil (0.5%) and WSF (40%), while stimulatory effect was observed at lower concentrations (0.01 and 0.1% of BHC and 5, 10% of WSF). WSF at higher concentrations (20 and 40%) caused reduction in DNA and RNA of the diatom. At lower concentrations it caused increase in protein and RNA content indicating increased metabolism. High concentrations of oil and its fraction had inhibitory effect on growth, protein content and nucleic acid content. This indicates that biosynthesis of these molecules may be probable targets for toxicity of oil
Role of annealing atmosphere on structure, dielectric and magnetic properties of La<SUB>2</SUB>CoMnO<SUB>6</SUB> and La<SUB>2</SUB>MgMnO<SUB>6</SUB>
Polycrystalline samples of La<SUB>2</SUB>MMnO<SUB>6</SUB> (M = Co and Mg) were prepared by a combined gel-combustion and high temperature reaction method. The samples were annealed in different oxygen partial pressure (p<SUB>O2</SUB>) and characterized by powder XRD, SQUID magnetometry, ac impedance spectroscopy, and electron paramagnetic resonance techniques. Monoclinic (P2<SUB>1</SUB>/n) and rhombohedral (Requation image) lattices were observed for La<SUB>2</SUB>CoMnO<SUB>6</SUB> and La<SUB>2</SUB>MgMnO<SUB>6</SUB>, respectively. On annealing in inert atmosphere, La<SUB>2</SUB>MgMnO<SUB>6</SUB> partially converted to monoclinic La<SUB>2</SUB>CoMnO<SUB>6</SUB> type structure, whereas no structural change was observed in La<SUB>2</SUB>CoMnO<SUB>6</SUB>. Dielectric studies of La2CoMnO6 indicated relaxor like behavior with polaronic conduction, which systematically decreased with the increase in p<SUB>2</SUB> of the annealing atmosphere. Magnetic studies indicated multiple ferromagnetic phase transitions in La<SUB>2</SUB>CoMnO<SUB>6</SUB> and a spin-glass like phase transition in La<SUB>2</SUB>MgMnO<SUB>6</SUB>. The fraction of ferromagnetic phases of La<SUB>2</SUB>CoMnO<SUB>6</SUB> was significantly dependent on the annealing environments. The variations of magnetic and dielectric properties of samples were related to the fluctuation of oxidation state of transition metal ions and oxygen vacancies in the samples
Optimized and validated spectrophotometric determination of two antifungal drugs in pharmaceutical formulations using an ion-pair complexation reaction
Abstracts of National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020
This book presents the abstracts of the papers presented to the Online National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020 (RDMPMC-2020) held on 26th and 27th August 2020 organized by the Department of Metallurgical and Materials Science in Association with the Department of Production and Industrial Engineering, National Institute of Technology Jamshedpur, Jharkhand, India.
Conference Title: National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020Conference Acronym: RDMPMC-2020Conference Date: 26–27 August 2020Conference Location: Online (Virtual Mode)Conference Organizer: Department of Metallurgical and Materials Engineering, National Institute of Technology JamshedpurCo-organizer: Department of Production and Industrial Engineering, National Institute of Technology Jamshedpur, Jharkhand, IndiaConference Sponsor: TEQIP-