611 research outputs found
ESTIMATING THE CONTRIBUTION OF THE FARGODOME TO THE AREA ECONOMY
Tourism has become an important economic sector in many parts of the world, and many regions, states, and local areas are increasingly looking to expenditures by visitors as a potential source of economic growth. Some communities have developed facilities to host sports events or other forms of entertainment to attract out-of-town visitors. Thus, the multi-purpose sports arena/auditorium has joined the industrial park as a community economic development initiative. This paper estimates the economic contribution of a multi-purpose sports and auditorium facility located in Fargo, North Dakota. Since opening its doors in December of 1992, the FARGODOME has hosted a wide variety of sporting events (e.g., college and high school football, rodeo, professional basketball), concerts, trade shows, and other forms of entertainment (e.g., ice shows, circuses, motor sports events). The purpose of this study was to estimate the contribution that FARGODOME event attendees and participants make to the Fargo area economy. The assessment process included (1) determining the residency and expenditure patterns of event attendees and participants, (2) estimating the aggregate direct economic contribution to the area economy by combining event attendee attributes and expenditures with FARGODOME records of the number of events held at the facility and attendance at each, and (3) estimating the secondary economic impacts associated with the FARGODOME's direct economic contribution. Event attendees' and participants' (e.g., exhibitors, athletes, and accompanying persons) place of residence and expenditures were obtained through intercept surveys of attendees/participants at selected FARGODOME events. The expenditures made directly by the FARGODOME to local entities (i.e., for payroll, benefits, utilities, etc.) were added to the attendees'/participants' expenditures outside the facility to arrive at the total direct economic impact (contribution) to the Fargo area. Then, the North Dakota Input-Output Model was used to estimate the secondary (multiplier) effects resulting from FARGODOME activities. Economic impacts will be reported using indicators such as gross business volume (gross receipts) of various economic sectors (e.g., retail trade), personal income, and employment.economic impacts, visitor spending, sports events, Public Economics, Resource /Energy Economics and Policy,
Numerical Simulations Reproduce Field Observations Showing Transient Weakening During Shear Zone Formation by Diffusional Hydrogen Influx and H2O Inflow
Exposures on HolsnĂžy island (Bergen Arcs, Norway) indicate fluid infiltration through fractures into a dry, metastable granulite, which triggered a kinetically delayed eclogitization, a transient weakening during fluid-rock interaction, and formation of shear zones that widened during shearing. It remains unclear whether the effects of grain boundary-assisted aqueous fluid inflow on the duration of granulite hydration were influenced by a diffusional hydrogen influx accompanying the fluid inflow. To better estimate the fluid infiltration efficiencies and the parameter interdependencies, a 1D numerical model of a viscous shear zone is utilized and validated using measured mineral phase abundance distributions and H2O-contents in nominally anhydrous minerals of the original granulite assemblage to constrain the hydration by aqueous fluid inflow and diffusional hydrogen influx, respectively. Both hydrations are described with a diffusion equation and affect the effective viscosity. Shear zone kinematics are constrained by the observed shear strain and thickness. The model fits the phase abundance and H2O-content profiles if the effective hydrogen diffusivity is approximately one order of magnitude higher than the diffusivity for aqueous fluid inflow. The observed shear zone thickness is reproduced if the viscosity ratio between dry granulite and deforming, reequilibrating eclogite is âŒ104 and that between dry granulite and hydrated granulite is âŒ102. The results suggest shear velocities <10â2 cm/a, hydrogen diffusivities of âŒ10â13±1 m2/s, and a shearing duration of <10 years. This study successfully links and validates field data to a shear zone model and highlights the importance of hydrogen diffusion for shear zone widening and eclogitization
Numerical Simulations Reproduce Field Observations Showing Transient Weakening During Shear Zone Formation by Diffusional Hydrogen Influx and H<sub>2</sub>O Inflow
Exposures on HolsnĂžy island (Bergen Arcs, Norway) indicate fluid infiltration through fractures into a dry, metastable granulite, which triggered a kinetically delayed eclogitization, a transient weakening during fluid-rock interaction, and formation of shear zones that widened during shearing. It remains unclear whether the effects of grain boundary-assisted aqueous fluid inflow on the duration of granulite hydration were influenced by a diffusional hydrogen influx accompanying the fluid inflow. To better estimate the fluid infiltration efficiencies and the parameter interdependencies, a 1D numerical model of a viscous shear zone is utilized and validated using measured mineral phase abundance distributions and H2O-contents in nominally anhydrous minerals of the original granulite assemblage to constrain the hydration by aqueous fluid inflow and diffusional hydrogen influx, respectively. Both hydrations are described with a diffusion equation and affect the effective viscosity. Shear zone kinematics are constrained by the observed shear strain and thickness. The model fits the phase abundance and H2O-content profiles if the effective hydrogen diffusivity is approximately one order of magnitude higher than the diffusivity for aqueous fluid inflow. The observed shear zone thickness is reproduced if the viscosity ratio between dry granulite and deforming, reequilibrating eclogite is âŒ104 and that between dry granulite and hydrated granulite is âŒ102. The results suggest shear velocities <10â2 cm/a, hydrogen diffusivities of âŒ10â13±1 m2/s, and a shearing duration of <10 years. This study successfully links and validates field data to a shear zone model and highlights the importance of hydrogen diffusion for shear zone widening and eclogitization
Residual Stresses in Tungsten Thin Films for Single Photon Detectors
The residual stress in 20 nm thick tungsten films deposited on silicon substrate by dc magnetron sputtering is investigated. The sample was held in a continuous flow cryostat, which was capable of achieving temperatures as low as 8 K. The cryostat was mounted on a goniometer to enable the angle-dispersive x-ray diffraction measurements. X-ray diffraction was used to monitor the shift of the α-W {110} Bragg reflection at room temperature and 8 K. From the shift of the {110} Bragg reflection, the total residual stress was estimated at about 6.0 GPa. After applying corrections for the thermal stress in the film, the residual intrinsic stress is estimated at 5.8 GPa
Spontaneous Thyroid Hemorrhage on Chronic Anticoagulation Therapy.
Even though highly vascularized, the thyroid gland rarely has spontaneous bleeding. Bleeding into the thyroid gland can result in potentially lethal acute airway compromise. This case report describes an elderly patient on warfarin for atrial fibrillation, who presented with swelling on the right side of her neck causing acute airway obstruction. An urgent computed tomography of the neck showed an enlarging hemorrhage into the right lobe of the thyroid gland. She was initially intubated for airway protection and her anticoagulation was reversed to stop the bleeding. She was closely monitored in the intensive care unit. After an uncomplicated tracheal extubation and recovery, she was discharged and scheduled for an elective total thyroidectomy. We desire that physicians be aware of this rare, potentially lethal bleeding complication
Guidance for the practical management of warfarin therapy in the treatment of venous thromboembolism
Factors Associated With Risk of Postdischarge Thrombosis in Patients With COVID-19
Importance: COVID-19 is associated with a high incidence of thrombotic events; however, the need for extended thromboprophylaxis after hospitalization remains unclear.
Objective: To quantify the rate of postdischarge arterial and venous thromboembolism in patients with COVID-19, identify the factors associated with the risk of postdischarge venous thromboembolism, and evaluate the association of postdischarge anticoagulation use with venous thromboembolism incidence.
Design, Setting, and Participants: This is a cohort study of adult patients hospitalized with COVID-19 confirmed by a positive SARS-CoV-2 test. Eligible patients were enrolled at 5 hospitals of the Henry Ford Health System from March 1 to November 30, 2020. Data analysis was performed from April to June 2021.
Exposures: Anticoagulant therapy after discharge.
Main Outcomes and Measures: New onset of symptomatic arterial and venous thromboembolic events within 90 days after discharge from the index admission for COVID-19 infection were identified using International Statistical Classification of Diseases and Related Health Problems, Tenth Revision codes.
Results: In this cohort study of 2832 adult patients hospitalized with COVID-19, the mean (SD) age was 63.4 (16.7) years (IQR, 53-75 years), and 1347 patients (47.6%) were men. Thirty-six patients (1.3%) had postdischarge venous thromboembolic events (16 pulmonary embolism, 18 deep vein thrombosis, and 2 portal vein thrombosis). Fifteen (0.5%) postdischarge arterial thromboembolic events were observed (1 transient ischemic attack and 14 acute coronary syndrome). The risk of venous thromboembolism decreased with time (Mann-Kendall trend test, Pâ\u3câ.001), with a median (IQR) time to event of 16 (7-43) days. There was no change in the risk of arterial thromboembolism with time (Mann-Kendall trend test, Pâ=â.37), with a median (IQR) time to event of 37 (10-63) days. Patients with a history of venous thromboembolism (odds ratio [OR],â3.24; 95% CI, 1.34-7.86), peak dimerized plasmin fragment D (D-dimer) level greater than 3 ÎŒg/mL (OR,â3.76; 95% CI, 1.86-7.57), and predischarge C-reactive protein level greater than 10 mg/dL (OR,â3.02; 95% CI, 1.45-6.29) were more likely to experience venous thromboembolism after discharge. Prescriptions for therapeutic anticoagulation at discharge were associated with reduced incidence of venous thromboembolism (OR,â0.18; 95% CI, 0.04-0.75; Pâ=â.02).
Conclusions and Relevance: Although extended thromboprophylaxis in unselected patients with COVID-19 is not supported, these findings suggest that postdischarge anticoagulation may be considered for high-risk patients who have a history of venous thromboembolism, peak D-dimer level greater than 3 ÎŒg/mL, and predischarge C-reactive protein level greater than 10 mg/dL, if their bleeding risk is low
Analyses of multidrug efflux pump-like proteins encoded on the Staphylococcus aureus chromosome
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