529 research outputs found

    Heron Visualisation Engine. Visualisation and dissemination of semantic cultural heritage data

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    Over the past two decades, there has been a proliferation of software to create great 3D models of archaeological sites and objects, and there has been plenty of thought and discussion on data models for finds. The results of those efforts have been made public through institutional websites and specific portals, but now, a further step is necessary: the cultural heritage data and (meta)data need to be taken into the semantic web. The Heritage Online Visualisation Engine (further: Heron VE) provides tools for documenting, visualising and disseminating the semantic relations between sites, objects, documentation and narratives. Heron VE is scalable: it can be used to tell the story of a particular archaeological complex, but it can also illustrate relations between sites and objects which are widely separated in both time and space. With Heron VE, dissemination of (meta)data can take many different forms: Heron VE contains modules for presenting and reporting on data, but it can also be used to provide data only, for example in several XML-formats or in N-triples. The designer of Heron VE has 25 years of experience with cultural heritage data in the field of archaeology, museums and libraries and has been working on the structured dissemination of cultural heritage data, first in the semantic web and now within the framework of linked data. This paper will illustrate the journey towards Heron VE, including considerations regarding the adoption, adaptation or rejection of existing data models and ontologies. It will also contain examples. These will mainly be based on data regarding sites of former castles and stately homes in the Netherlands, but it will become very clear that the Heron VE can be applied to many different cultural heritage datasets, including those regarding ancient urban areas

    Binding of small interfering RNA molecules is crucial for RNA interference suppressor activity of rice hoja blanca virus NS3 in plants

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    The NS3 protein of rice hoja blanca tenuivirus represents a viral suppressor of RNAi that sequesters small interfering (si)RNAs in vitro. To determine whether this siRNA binding property is the critical determinant for the suppressor activity of NS3, an alanine point mutational analysis was performed and the resulting mutant proteins were tested for both siRNA binding ability and RNAi suppressor activity in plants. Alanine substitutions of lysine residues at position 173-175 resulted in mutant proteins that lost both their affinity for siRNAs and their RNAi suppressor activity in planta. This indicates that siRNA binding of NS3 is indeed essential for the suppressor function of NS3 and that residues at position 173-175 are involved in the siRNA binding and suppressor activit

    Primary Graft Dysfunction after LungTransplantation

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    __Abstract__ The human body requires oxygen to perform aerobic processes 1-3. The lungs are the respiratory organs that not only supply oxygen to the blood, but also remove carbon dioxide from the body. The right lung is most commonly made up of three lobes (superior, middle and inferior) relatively separated by fissures, while the left lung consists of two lobes (superior and inferior). Every lobe is again divided in several bronchopulmonary segments, which are the largest subdivisions of a lobe and named according to the segmental bronchi supplying them. The bronchial tree consists of a conducting zone (bronchi, bronchioles and terminal bronchioles) and a respiratory zone (respiratory bronchioles and the alveolar duct). The alveolar ducts terminate in the alveolar sac which gives rise to several pulmonary alveoli. The conducting zone not only transports gases, it also plays a role in the host defense system, and it warms and humidifies inspired air. It has its own circulation, known as the bronchial circulation, which comes from the descending aorta and drains into the pulmonary veins. Gas exchange occurs in the respiratory zone. A pair of normal lungs contains between 400 and 700 million alveoli. If stretched, this contains an area of 70 m2. The pulmonary circulation has its origin in the pulmonary trunk, that carries deoxygenated but carbon dioxide rich blood to the lungs. The pulmonary trunk divides in a right and left pulmonary artery that enter the pulmonary cavities at the pulmonary hilum. After branching several times, the pulmonary arteries terminate in capillaries that surround the alveolus. After gas excha

    Morphological modelling of the Western Scheldt: validation of DELFT3D

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    Morphological changes of the Scheldt estuary are extensively monitored by the Dutch and Belgian authorities. To predict effects of long-term natural changes (sea level rise) and the consequences of various human interventions, such as dredging/dumping/sand mining and deepening of the navigation channel, there is an urgent need for adequate and reliable tools in these matters. The present report describes the results of the calibration and verification of the DEFLT3D morphological model for the Western Scheldt on the short term (years) as well as on the mid term (decades)
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