8 research outputs found
Hopes and Fears: Community cohesion and the ‘White working class’ in one of the ‘failed spaces’ of multiculturalism
Since 2001, community cohesion has been an English policy concern, with accompanying media discourse portraying a supposed failure by Muslims to integrate. Latterly, academia has foregrounded White majority attitudes towards ethnic diversity, particularly those of the ‘White working class’. Whilst questioning this categorisation, we present data on attitudes towards diversity from low income, mainly White areas within Dewsbury, West Yorkshire, a town portrayed in media discourse as one of the ‘failed spaces’ of multiculturalism. Drawing on mixed methods research, we present and discuss data that provide a complex message, seemingly confirming pessimistic analyses around ethnic diversity and predominantly White neighbourhoods but also highlighting an appetite within the same communities for greater and more productive inter-ethnic contact. Furthermore, anxieties about diversity and integration have largely failed to coalesce into broad support for organised anti-minority politics manifest in groups such as the English Defence League
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Cluster headache genome-wide association study and meta-analysis identifies eight loci and implicates smoking as causal risk factor.
OBJECTIVE: Aggregating data for the first genome-wide association study meta-analysis of cluster headache, to identify genetic risk variants and gain biological insights. METHODS: A total of 4,777 cases (3,348 men and 1,429 women) with clinically diagnosed cluster headache were recruited from ten European and one East Asian cohorts. We first performed an inverse-variance genome-wide association meta-analysis of 4,043 cases and 21,729 controls of European ancestry. In a secondary trans-ancestry meta-analysis we included 734 cases and 9,846 controls of East Asian ancestry. Candidate causal genes were prioritized by five complementary methods: expression quantitative trait loci, transcriptome-wide association, fine-mapping of causal gene sets, genetically driven DNA methylation, and effects on protein structure. Gene set and tissue enrichment analyses, genetic correlation, genetic risk score analysis and Mendelian randomization were part of the downstream analyses. RESULTS: The estimated SNP-based heritability of cluster headache was 14.5%. We identified nine independent signals in seven genome-wide significant loci in the primary meta-analysis, and one additional locus in the trans-ethnic meta-analysis. Five of the loci were previously known. The 20 genes prioritized as potentially causal for cluster headache showed enrichment to artery and brain tissue. Cluster headache was genetically correlated with cigarette smoking, risk-taking behavior, ADHD, depression and musculoskeletal pain. Mendelian randomization analysis indicated a causal effect of cigarette smoking intensity on cluster headache. Three of the identified loci were shared with migraine. INTERPRETATION: This first genome-wide association study meta-analysis gives clues to the biological basis of cluster headache and indicates that smoking is a causal risk factor. This article is protected by copyright. All rights reserved
Crossing the Line ? White young people and Community Cohesion
The emergence of community cohesion as a British policy priority has represented a discursive shift in approaches to race relations, the emphasis on ethnic diversity downplayed in favour of commonality, shared values and the promotion of national identity. Central to community cohesion has been a focus on ‘contact’ as a way of overcoming ‘parallel lives’, and the need for communities to take responsibility within processes of contact and dialogue. The political focus, echoing past assimilationist discourses, has been on an alleged lack of integration on the part of Muslims; by contrast little attention is paid to how white working class young people view the contact central to cohesion strategies. This paper draws on case study evidence from Oldham and Rochdale, Greater Manchester to interpret the limited support the young white respondents have for, cross-ethnic contact, and the relevance of class experience to these views
White like them: Whiteness and anachronistic space in representations of the English white working class
Intermittent reservoir daily-inflow prediction using lumped and distributed data multi-linear regression models
Overcoming intolerance to young people's conduct: Implications from the unintended consequences of policy in the UK
This paper takes the opportunity to reflect upon the trajectory and consequences of the anti-social behaviour policy framework in the United Kingdom (UK) from its inception to date. It contends that despite, and paradoxically because of, the interventions launched to confront anti-social behaviours, perceptions of these behaviours have remained stubborn to improvement. In effect, anti-social behaviour policy has fed negative stereotypes of youth and positioned young people as a metaphor for deeper social malaise. The paper suggests a theoretical framework for understanding the mechanisms through which this perverse consequence has been realized. This task is facilitated conceptually through an exploration of the meaning of tolerance and the considerations that inform (in)tolerant assessments by citizens. Further, we progress to consider evidence of the interplay between these assessments and forces impacting upon social (dis)connectedness in the UK. This enables us to demonstrate how the anti-social behaviour policy suite underpins the intolerance of youth