Application of the Mutual Information to the Zn Gauge Model

We introduce the mutual information to the Zn lattice gauge theory for testing the degree of correlations. It is shown that our simulation result for the plaquettes gives a clear peak on the critical point

IR Absorption Nnalysis of Oxidation Behaviors of Nano-composite Phases with β-FeSi2 Nanocrystals and Si

We have investigated oxidation behaviors of nano-composite phase with β-FeSi2 nanocrystals (β-NCs) and Si on Si substrates. IR absorption measurements revealed that only oxidation of Si into SiO2 proceeded in the nano-composite phase. This fact is very important for realization of a novel composite phase with β-NCs and SiO2, which may contribute to enhancement of light emission and to prevent a large thermal quenching of light emission observed in the composite phase with β-NCs and Si.International Conference and Summer School on Advanced Silicide Technology 2014, July 19–21, 2014, Tokyo, Japa

Photoluminescence Enhancement of β-FeSi2 Nanocrystals Controlled by Transport of Holes in Cu-doped n-type Si Substrates

We have investigated PL behavior of β-FeSi2 nanocrystals controlled by transport of holes in Cu-doped n-type Si substrates. PL enhancement was observed and PCI-PL measurements revealed that PL enhancement was attributed to a transport process of holes with a larger time constant in Cu-doped n-Si substrate in which an interval trap process is controlled by Cu doping.International Conference and Summer School on Advanced Silicide Technology 2014, July 19–21, 2014, Tokyo, Japa

Enhancement of Photoluminescence from Cu-doped β-FeSi2/Si Heterostructures

We have investigated photoluminescence (PL) behaviors of the Cu-doped β-FeSi2 thin film/Si heterostructure. Pronounced enhancement of an intrinsic A band and an impurity-related C band emissions has been observed in all the Cu-doped samples. The photo-carrier injection (PCI)-PL measurements have revealed that the PL enhancement is attributed to dynamic process of migration of holes where a repeated trap process of holes can be controlled by Cu-doping.International Conference and Summer School on Advanced Silicide Technology 2014, July 19–21, 2014, Tokyo, Japa

Photoluminescence Property of Nano-composite Phases of β-FeSi2 Nanocrystals Embedded in SiO2

We have investigated photoluminescence (PL) behaviors of nano-composite phase of β-NCs embedded in SiO2 (β-NCs/SiO2). The inhomogeneous spectra consisting of the A, B, and C emission bands were observed. PL enhancement also was confirmed in comparison with β-NCs/Si. Under high pumping rate, we observed PL spectra near room temperatures (~270 K). This fact means that oxidation of the nano-composite phase can contribute to reduction of thermal quenching, which may come from increase of band offsets around β-NCs.International Conference and Summer School on Advanced Silicide Technology 2014, July 19–21, 2014, Tokyo, Japa

Structural conversion from bowl- to ball-type polyoxovanadates: Synthesis of a spherical tetradecavanadate through a chloride-incorporated bowl-type dodecavanadate

A spherical tetradecavanadate, [V14O38(Cl)] 7-, was synthesized from a chloride-incorporated bowl-type dodecavanadate. © 2014 Elsevier B.V. All rights reserved

Formation of vv lacunary polyoxovanadates and interconversion reactions of dodecavanadate species

金沢大学理工研究域物質化学系Oxidation, reactions of the reduced decavanadate [VIV2Vv8O26]4- (1) with halide guest anions were investigated for the synthesis of Vv host molecules. The reaction with Cl- afforded a new dodecavanadate, [HVV12O32(C1)]4-(3), which incorporated the guest chloride anion. The polyoxovanadate framework of 3 is different from, the bowl-shaped dodecavanadate [VV12O 32(CH3CN)]4- (2). The structure of 3 is regarded as a trilacunary counterpart of the pentadecavanadate [V V9VIV8O36C1] 4-. Employment: of an F-template yielded the layered polyoxovanadate [HVV11O29F2] 4- (4). The framework of 4 is a monolacunary structure of the fluoride-incorporated dodecavanadate [H6VV2VIv10O30F2] 6-, in which one of the VO groups at the belt position is removed. The three vana-dium atoms in the capping units are connected, by (μ3-F bridges. Reaction with Br provided [HVv12O32(Br)]4- (5) with minor formation of [H3VV10O28]3- Interconversion reactions between 2, 3, and 4 proceeded as follows: the reaction of 2 with Cl- prompted, an isomerization reaction of the bowl-type framework, affording 3; the reaction of 3 with F- gave 4; the reaction of 4 with CH3CN reproduced acetonitrile-incorporated 2. Complexes 3 and 4 were characterized by X-ray analysis. Polyoxovanadates 3 and 4, with the highest oxidation cores, exhibited distinct signals in the 51V NMR spectra, corresponding to lacunary polyoxovanadate geometries. © Wiley-VCH Verlag GmbH & Co. KGaA

Modulation of porcine intestinal epitheliocytes immunetranscriptome response by Lactobacillus jensenii TL2937

In order to evaluate probiotic strains applicable for the beneficial immunomodulation of the porcine gut (immunobiotics), we previously developed a porcine intestinal epitheliocyte cell line (PIE cells). Here, transcriptomic studies using PIE cells were performed considering that this information would be valuable for understanding the mechanisms involved in the protective activity of the immunobiotic strain Lactobacillus jensenii TL2937 against intestinal inflammatory damage in pigs. In addition, those studies would provide criteria for selecting biomarkers for the screening of new immunobiotic strains. We performed microarray analysis to investigate the transcriptomic response of PIE cells to the challenge with heat-stable Enterotoxigenic Escherichia coli (ETEC) pathogen-associated molecular patterns (PAMPs) and, the changes induced by L. jensenii TL2937 in that response. The approach allowed us to obtain a global overview of the immune genes involved in the response of PIE cells to heat-stable ETEC PAMPs. We observed that L. jensenii TL2937 differently modulated gene expression in ETEC PAMPs-challenged PIE cells. Microarray and RT-PCR analysis indicated that the most remarkable changes in PIE cells transcriptomic profile after heat-stable ETEC PAMPs challenge were observed in chemokines, adhesion molecules, complement and coagulation cascades factors. In addition, an anti-inflammatory effect triggered by TL2937 strain in PIE cells was clearly demonstrated. The decrease in the expression of chemokines (CCL8, CXCL5, CXCL9, CXCL10, and CXCL11), complement (C1R, C1S, C3, and CFB), and coagulation factors (F3) by L. jensenii TL2937 supports our previous reports on the immunoregulatory effect of this strain. These results provided clues for the better understanding of the mechanism underlying host-immunobiotic interaction in the porcine host. The comprehensive transcriptomic profiles of PIE cells provided by our analyses successfully identified a group of genes, which could be used as prospective biomarkers for the screening and evaluation of new anti-inflammatory immunobiotics for the prevention of inflammatory intestinal disorders in pigs.Fil: Kobayashi, Hisakazu. Tohoku University; JapónFil: Albarracín, Leonardo Miguel. Tohoku University; Japón. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaFil: Sato, Nana. Tohoku University; JapónFil: Kanmani, Paulraj. Tohoku University; JapónFil: Kober, Humayun A.K.M.. Tohoku University; Japón. Chittagong Veterinary and Animal Sciences University. Department of Dairy and Poultry Science; BangladeshFil: Ikeda-Ohtsubo, Wakako. Tohoku University; JapónFil: Suda, Yoshihito. Miyagi University; JapónFil: Nochi, Tomonori. Tohoku University; JapónFil: Aso, Hisashi. Tohoku University; JapónFil: Makino, Seiya. Meiji Co., Ltd. Food Science Research Labs.; JapónFil: Kano, Hiroshi. Meiji Co., Ltd. Food Science Research Labs.; JapónFil: Ohkawara, Sou. Meiji Seika Pharma Co., Ltd. Agricultural and Veterinary Division; JapónFil: Saito, Tadao. Tohoku University; JapónFil: Villena, Julio Cesar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina. Tohoku University; JapónFil: Kitazawa, Haruki. Tohoku University; Japó

Methylxanthine sensitization of human colon cancer cells to 186Re-labeled monoclonal antibody

金沢大学大学院医学系研究科Tumor cells lacking the functional p53 suppressor gene may arrest at the G2 phase of the cell cycle after exposure to ionizing radiation, resulting in increased radioresistance. Methylxanthines (MTXs), such as pentoxifylline (PTX) or caffeine (CAF), can inhibit the G2-phase checkpoint arrest of damaged cells and thus radiosensitize them. However, the effect of MTX in cells irradiated with low-dose-rate β-emission is not well understood. Methods: A clonogenic assay was performed with LS180 human colon cancer cells lacking the functional p53 suppressor gene. Cells were irradiated with increasing concentrations of 186Re-mercaptoacetyltriglycine (186Re-MAG3)-labeled A7 monoclonal antibody against colorectal cancer (0-925 kBq/mL) at 37°C in 5% CO2 for 24 h in the presence or absence of PTX (0-2 mmol/L) or CAF (0-5 mmol/L). The enhancement ratio (ER) with MTX was calculated as a ratio of 50% cell-killing concentration of 186Re-MAG3-A7 in control cells to that in cells treated with PTX or CAF. The cell cycle distribution was analyzed with a flow cytometer. Results: The concentration of 50% cell kill was 474 kBq/mL 186Re-MAG3-A7. Both PTX and CAF dose dependently enhanced the cytotoxicity of 186Re-MAG3-A7: ERs of 0.5 mmol/L PTX, 2 mmol/L PTX, 1 mmol/L CAF, and 5 mmol/L CAF were 1.50, 2.18, 1.54, and 2.63, respectively. Flow cytometry showed that the percentage nonirradiated cells in the G2/M phase of the cell cycle was 11.3% ± 1.66%. On the other hand, cells exposed to 186Re-MAG3-A7 accumulated in the G2/M phase of the cell cycle (40.2% ± 1.46%), which was inhibited by the presence of 1 mmol/L PTX (19.8% ± 8.12%) or 2 mmol/L CAF (26.9% ± 6.21%). Conclusion: Cellular modulation of the cell cycle with PTX and CAF radiosensitized LS180 colon cancer cells exposed to 186Re radiation