72 research outputs found

    Double vs single internal thoracic artery harvesting in diabetic patients: role in perioperative infection rate

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    Background: The aim of this prospective study is to evaluate the role in the onset of surgical site infections of bilateral internal thoracic arteries harvesting in patients with decompensated preoperative glycemia. Methods: 81 consecutive patients with uncontrolled diabetes mellitus underwent elective CABG harvesting single or double internal thoracic arteries. Single left ITA was harvested in 41 patients (Group 1, 50.6%), BITAs were harvested in 40 (Group 2, 49.4%). The major clinical end points analyzed in this study were infection rate, type of infection, duration of infection, infection relapse rate and total hospital length of stay. Results: Five patients developed sternal SSI in the perioperative period, 2 in group 1 and 3 in group 2 without significant difference. All sternal SSIs were superficial with no sternal dehiscence. The development of infection from the time of surgery took 18.5 ± 2.1 and 7.3 ± 3.0 days for Groups 1 and 2 respectively. The infections were treated with wound irrigation and debridement, and with VAC therapy as well as with antibiotics. The VAC system was removed after a mean of 12.8 ± 5.1 days, when sterilization was achieved. The overall survival estimate at 1 year was 98.7%. Only BMI was a significant predictor of SSI using multivariate stepwise logistic regression analysis (Odds Ratio: 1.34; 95%Conficdence Interval: 1.02–1.83; p value: 0.04). In the model, the use of BITA was not an independent predictor of SSI. Conclusion: CABG with bilateral pedicled ITAs grafting could be performed safely even in diabetics with poor preoperative glycaemic control

    Moving Your Sons to Safety: Galls Containing Male Fig Wasps Expand into the Centre of Figs, Away From Enemies

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    Figs are the inflorescences of fig trees (Ficus spp., Moraceae). They are shaped like a hollow ball, lined on their inner surface by numerous tiny female flowers. Pollination is carried out by host-specific fig wasps (Agaonidae). Female pollinators enter the figs through a narrow entrance gate and once inside can walk around on a platform generated by the stigmas of the flowers. They lay their eggs into the ovules, via the stigmas and styles, and also gall the flowers, causing the ovules to expand and their pedicels to elongate. A single pollinator larva develops in each galled ovule. Numerous species of non-pollinating fig wasps (NPFW, belonging to other families of Chalcidoidea) also make use of galled ovules in the figs. Some initiate galls, others make use of pollinator-generated galls, killing pollinator larvae. Most NPFW oviposit from the outside of figs, making peripherally-located pollinator larvae more prone to attack. Style length variation is high among monoecious Ficus spp. and pollinators mainly oviposit into more centrally-located ovules, with shorter styles. Style length variation is lower in male (wasp-producing) figs of dioecious Ficus spp., making ovules equally vulnerable to attack by NPFW at the time that pollinators oviposit

    Platform for Plasmodium vivax vaccine discovery and development

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    Plasmodium vivax is the most prevalent malaria parasite on the American continent. It generates a global burden of 80-100 million cases annually and represents a tremendous public health problem, particularly in the American and Asian continents. A malaria vaccine would be considered the most cost-effective measure against this vector-borne disease and it would contribute to a reduction in malaria cases and to eventual eradication. Although significant progress has been achieved in the search for Plasmodium falciparum antigens that could be used in a vaccine, limited progress has been made in the search for P. vivax components that might be eligible for vaccine development. This is primarily due to the lack of in vitro cultures to serve as an antigen source and to inadequate funding. While the most advanced P. falciparum vaccine candidate is currently being tested in Phase III trials in Africa, the most advanced P. vivax candidates have only advanced to Phase I trials. Herein, we describe the overall strategy and progress in P. vivax vaccine research, from antigen discovery to preclinical and clinical development and we discuss the regional potential of Latin America to develop a comprehensive platform for vaccine development

    Stochastic Modelling of Daily Rainfall for Sout West Monsoon Season of Bapatla, Andhra Pradesh

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    The daily rainfall data for the year of 1988 to 2002 were used to develop stochastic models for Southwest monsoon season of Bapatla. The periodic component in the time series was determined by Fourier analysis and removed. The series were modelled by autoregressive (AR) and autoregressive moving average (ARMA) family of models. The goodness of fit of models were. tested by Box-Pierce Portmonteau test, Akaike Information Criterion, and criteria of good ness of fit tests. Based on goodness of fit tests, AR (2) and ARMA (2, 2) models were selected for daily rainfall of the Southwest monsoon season of Bapatla

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    S Singh, KN Raja, I Ganguly and R Arora (2015) Association of the microsatellite marker with body biometric parameters in Koraput sheep of Odisha Indian Hournal of Tropical Agriculture 33 (2) : 1735 - 1740.Not AvailableNot Availabl

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    S Singh, KN Raja, I Ganguly, R Arora and RS Kataria (2015) Genetic characterization of Koraput sheep of Odisha Indian Journal of Animal Sciences 85 (6) : 667 - 669.Not AvailableNot Availabl

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    S Ahlawat, R Sharma A Maitra, KN Raja, NK Verma and MS Tantia (2015) Prolificacy in Indian goat breeds is independent of FecB mutation Indian Journal of Animal Sciences 85 (6) : 617 - 620.Not AvailableNot Availabl

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