Measuring agreement of administrative data with chart data using prevalence unadjusted and adjusted kappa

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Intersection of inflammation and herbal medicine in the treatment of osteoarthritis

Herbal remedies and dietary supplements have become an important area of research and clinical practice in orthopaedics and rheumatology. Understanding the risks and benefits of using herbal medicines in the treatment of arthritis, rheumatic diseases, and musculoskeletal complaints is a key priority of physicians and their patients. This review discusses the latest advances in the use of herbal medicines for treating osteoarthritis (OA) by focusing on the most significant trends and developments. This paper sets the scene by providing a brief introduction to ethnopharmacology, Ayurvedic medicine, and nutrigenomics before discussing the scientific and mechanistic rationale for targeting inflammatory signalling pathways in OA by use of herbal medicines. Special attention is drawn to the conceptual and practical difficulties associated with translating data from in-vitro experiments to in-vivo studies. Issues relating to the low bioavailability of active ingredients in herbal medicines are discussed, as also is the need for large-scale, randomized clinical trial

Estimation of population proportion in randomized response sampling using weighted confidence interval construction

[[abstract]]This paper considers the problem of estimation for binomial proportions of sensitive attributes in the population of interest. Randomized response techniques are suggested for protecting the privacy of respondents and reducing the response bias while eliciting information on sensitive attributes. By applying the Wilson (J Am Stat Assoc 22:209–212, 1927) score approach for constructing confidence intervals, various probable point estimators and confidence interval estimators are suggested for the common structures of randomized response procedures. In addition, efficiency comparisons are carried out to study the performances of the proposed estimators for both the cases of direct response surveys and randomized response surveys. Circumstances under which each proposed estimators is better are also identified.[[notice]]補正完畢[[journaltype]]國外[[incitationindex]]SCI[[booktype]]電子版[[booktype]]紙本[[countrycodes]]DE