13 research outputs found
Impaired Bone Health in Inflammatory Bowel Disease: A Case-Control Study in 80 Pediatric Patients
Peer reviewe
Peripheral quantitative computed tomography (pQCT) for the assessment of bone strength in most of bone affecting conditions in developmental age: a review
Gamma-gliadin specific celiac disease antibodies recognize p31-43 and p57-68 alpha gliadin peptides in deamidation related manner as a result of cross-reaction
Nutritional status and body composition in children with inflammatory bowel disease: a prospective, controlled, and longitudinal study
Impaired Bone Health in Inflammatory Bowel Disease: A CaseâControl Study in 80 Pediatric Patients
Psychological wellbeing and physical activity in children and adolescents with inflammatory bowel disease compared to healthy controls
Abstract Background Children and adolescents with inflammatory bowel disease (IBD) report impairments in daily activities, social interactions and coping. Findings regarding psychological functioning are inconsistent, while limited information is available on objectively assessed physical activity (PA). The aims of the present study were therefore to compare anthropometric dimensions, blood values, psychological functioning and PA of children and adolescents with IBD with healthy controls. Methods Forty-seven children and adolescents took part in the study. Of these, 23 were diagnosed with IBD (mean age: 13.88Â years, 44% females). The IBD group was divided into a medically well adjusted âremission-groupâ (nâ=â14; IBD-RE) and a group with an âactive stateâ of disease (nâ=â8; IBD-AD). Healthy controls (nâ=â24; HC) were age- and gender-matched. Participantsâ anthropometric data, blood values and objective PA were assessed. Further, participants completed questionnaires covering socio-demographic data and psychological functioning. Results Participants with IBD-AD showed higher erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) values, haemoglobin, and leukocyte values. IBD-AD had poorer psychological functioning and lower PA (average steps per day) compared to IBD-RE and HC. No mean differences were found between IBD-RE and HC. Conclusions The pattern of results suggests that effective medical treatment of IBD in children and adolescents is associated with favorable physiological parameters, psychological dimensions and PA. Psychological counselling of children and adolescents in an active state of IBD seem to be advised in addition to standard treatment schedules. Trial registration NCT NCT02264275 ; Registered 8 October 2014