Mesenchymal Stem Cell Responses to Bone-Mimetic Electrospun Matrices Composed of Polycaprolactone, Collagen I and Nanoparticulate Hydroxyapatite

The performance of biomaterials designed for bone repair depends, in part, on the ability of the material to support the adhesion and survival of mesenchymal stem cells (MSCs). In this study, a nanofibrous bone-mimicking scaffold was electrospun from a mixture of polycaprolactone (PCL), collagen I, and hydroxyapatite (HA) nanoparticles with a dry weight ratio of 50/30/20 respectively (PCL/col/HA). The cytocompatibility of this tri-component scaffold was compared with three other scaffold formulations: 100% PCL (PCL), 100% collagen I (col), and a bi-component scaffold containing 80% PCL/20% HA (PCL/HA). Scanning electron microscopy, fluorescent live cell imaging, and MTS assays showed that MSCs adhered to the PCL, PCL/HA and PCL/col/HA scaffolds, however more rapid cell spreading and significantly greater cell proliferation was observed for MSCs on the tri-component bone-mimetic scaffolds. In contrast, the col scaffolds did not support cell spreading or survival, possibly due to the low tensile modulus of this material. PCL/col/HA scaffolds adsorbed a substantially greater quantity of the adhesive proteins, fibronectin and vitronectin, than PCL or PCL/HA following in vitro exposure to serum, or placement into rat tibiae, which may have contributed to the favorable cell responses to the tri-component substrates. In addition, cells seeded onto PCL/col/HA scaffolds showed markedly increased levels of phosphorylated FAK, a marker of integrin activation and a signaling molecule known to be important for directing cell survival and osteoblastic differentiation. Collectively these results suggest that electrospun bone-mimetic matrices serve as promising degradable substrates for bone regenerative applications

Determination Of Radome Panel Performance Based On Electromagnetic Material Characterisation Data For DWR Radome

Electromagnetic Power Trarfsmission And Reflection Performances,Based On Material Characterisation Done At Cusat, Cochin, Are Predicted For The A-Sandwich Radome Panels Fabricated At Nal.Similar Studies Are Also Conducted For Ideally Fabricatedn Panels Which Adheres To The Specifications Of Nal Radome Design Team . These Analyses Show That There Is No Appreciable Difference In The Radome Panel Performace, Either Due To Fabrication Uncertainties, Or Between The Fabrication Processes And Materials,To The Levels Observed In This Study

Preliminary EM Design Studies for A-Sandwich DWR Radome

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Broadband Suspended Microstrip Antenna For Circular Polarization

In this paper we propose a circularly polarized (CP) microstrip antenna on a suspended substrate with a coplanar capacitive feed and a slot within the rectangular patch. The antenna has an axial ratio bandwidth (< 3 dB) of 7.1%. The proposed antenna exhibits a much higher impedance bandwidth of about 49% (S11 < -10 dB) and also yields return loss better than -15 dB in the useful range of circular polarization. Measured characteristics of the antenna are in good agreement with the simulated results. The radiation patterns indicate good cross polarization rejection and low back lobe radiations. The design proposed here can be scaled to any frequency of interest

Radar Absorbing Materials (RAM): A Cross-Indexed Bibliography (1956-1993)

Abstract attached as PD

Evaluation of Fock-type Integrals and Airy Functions for UTD Applications

Abstract attached as PD

Electromagnetic Characterisation of Materials for DWR Radome

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Trends in radar absorbing materials technology

The research in the area of Radar Absorbing Materials RAMs) has been actively pursued for at least four decades. Although resonant RAMs were originally designed by transmission line approach, and the broad band RAMs were obtained by multilayering, the quest for ultrawide band performance has led to novel approaches such as chirality and even exploring biochemical products. It is observed that radome materials are frequently used as RAMs. The understanding of the underlying principles of electromagnetic analysis and design, fabrication and the trends in RAMs reviewed in this paper could lead to indigenisation, and even pioneering next generation of RAM technology

Shaping Analysis for Radar Cross Section (RCS) Reduction for Missiles: Annual Technical Report (1995-1996)

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Lossy Model EM Design Studies for DWR Radome

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