A quantum protocol to win the graph colouring game on all Hadamard graphs

This paper deals with graph colouring games, an example of pseudo-telepathy, in which two provers can convince a verifier that a graph $G$ is $c$-colourable where $c$ is less than the chromatic number of the graph. They win the game if they convince the verifier. It is known that the players cannot win if they share only classical information, but they can win in some cases by sharing entanglement. The smallest known graph where the players win in the quantum setting, but not in the classical setting, was found by Galliard, Tapp and Wolf and has 32,768 vertices. It is a connected component of the Hadamard graph $G_N$ with $N=c=16$. Their protocol applies only to Hadamard graphs where $N$ is a power of 2. We propose a protocol that applies to all Hadamard graphs. Combined with a result of Frankl, this shows that the players can win on any induced subgraph of $G_{12}$ having 1609 vertices, with $c=12$. Combined with a result of Frankl and Rodl, our result shows that all sufficiently large Hadamard graphs yield pseudo-telepathy games.Comment: 5pag

Response of a stretched cylindrical diffusion flame to a sinusoidal velocity oscillation of air stream

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乳酸菌Lactobacillus plantarum AYAの免疫賦活効果と作用機序解析

学位の種別: 論文博士審査委員会委員 : （主査）東京大学特任准教授 岡田 晋治, 東京大学教授 佐藤 隆一郎, 東京大学特任教授 朝倉 富子, 東京大学准教授 八村 敏志, 国立感染症研究所免疫部第四室長 高橋 宜聖University of Tokyo(東京大学

Weakly bound molecules as sensors of new gravitylike forces

Several extensions to the Standard Model of particle physics, including light dark matter candidates and unification theories predict deviations from Newton’s law of gravitation. For macroscopic distances, the inverse-square law of gravitation is well confirmed by astrophysical observations and laboratory experiments. At micrometer and shorter length scales, however, even the state-of-the-art constraints on deviations from gravitational interaction, whether provided by neutron scattering or precise measurements of forces between macroscopic bodies, are currently many orders of magnitude larger than gravity itself. Here we show that precision spectroscopy of weakly bound molecules can be used to constrain non-Newtonian interactions between atoms. A proof-of-principle demonstration using recent data from photoassociation spectroscopy of weakly bound Yb2 molecules yields constraints on these new interactions that are already close to state-of-the-art neutron scattering experiments. At the same time, with the development of the recently proposed optical molecular clocks, the neutron scattering constraints could be surpassed by at least two orders of magnitude

Effectiveness of Anti-PD-1 Antibody Monotherapy for the Primary Malignant Melanoma of the Esophagus： A Case Report

Primary malignant melanoma of the esophagus（PMME）is extraordinarily rare with a high degree of malignancy and poor prognosis, and a standard therapy remains to be established. The anti-PD-1 antibody nivolumab is a promising agent for various cancers. To our knowledge, this is the first case report of PMME where a complete response was achieved using nivolumab. We report an 80-year-old woman who was diagnosed with PMME with bone metastasis and lymph node metastases. Although dacarbazine combined chemotherapy was performed and continued for six cycles, the primary tumor progressed and liver metastases appeared. The patient then received nivolumab monotherapy. After three cycles, nivolumab monotherapy for PMME resulted in a complete response as shown by positron emission tomography, computed tomography, and esophagogastroduodenoscopy. In our case, nivolumab exerted a curative effect on PMME, thus suggesting that nivolumab can be effective in the treatment of this rare disease

Association between hand-grip strength and depressive symptoms: Locomotive Syndrome and Health Outcomes in Aizu Cohort Study (LOHAS).

First published online: February 21, 2015no study has examined the longitudinal association between hand-grip strength and mental health, such as depressive symptoms

Experimental model for the irradiation-mediated abscopal effect and factors influencing this effect

Radiotherapy (RT) is the primary treatment for cancer. Ionizing radiation from RT induces tumor damage at the irradiated site, and, although clinically infrequent, may cause regression of tumors distant from the irradiated site-a phenomenon known as the abscopal effect. Recently, the abscopal effect has been related to prolongation of overall survival time in cancer patients, though the factors that influence the abscopal effect are not well understood. The aim of this study is to clarify the factors influencing on abscopal effect. Here, we established a mouse model in which we induced the abscopal effect. We injected MC38 (mouse colon adenocarcinoma) cells subcutaneously into C57BL/6 mice at two sites. Only one tumor was irradiated and the sizes of both tumors were measured over time. The non-irradiated-site tumor showed regression, demonstrating the abscopal effect. This effect was enhanced by an increase in the irradiated-tumor volume and by administration of anti-PD1 antibody. When the abscopal effect was induced by a combination of RT and anti-PD1 antibody, it was also influenced by radiation dose and irradiated-tumor volume. These phenomena were also verified in other cell line, B16F10 cells (mouse melanoma cells). These findings provide further evidence of the mechanism for, and factors that influence, the abscopal effect in RT