4,248 research outputs found
Extended Gravity Theories and the Einstein-Hilbert Action
I discuss the relation between arbitrarily high-order theories of gravity and
scalar-tensor gravity at the level of the field equations and the action. I
show that -order gravity is dynamically equivalent to Brans-Dicke
gravity with an interaction potential for the Brans-Dicke field and further
scalar fields. This scalar-tensor action is then conformally equivalent to the
Einstein-Hilbert action with scalar fields. This clarifies the nature and
extent of the conformal equivalence between extended gravity theories and
general relativity with many scalar fields.Comment: 12 pages, Plain Latex, SUSSEX-AST-93/7-
Remifentanil does not impair left ventricular systolic and diastolic function in young healthy patients
Background Experimental studies and investigations in patients with cardiac diseases suggest that opioids at clinical concentrations have no important direct effect on myocardial relaxation and contractility. In vivo data on the effect of remifentanil on myocardial function in humans are scarce. This study aimed to investigate the effects of remifentanil on left ventricular (LV) function in young healthy humans by transthoracic echocardiography (TTE). We hypothesized that remifentanil does not impair systolic, diastolic LV function, or both. Methods Twelve individuals (aged 18-48 yr) without any history or signs of cardiovascular disease and undergoing minor surgical procedures under general anaesthesia were studied. Echocardiographic examinations were performed in the spontaneously breathing subjects before (baseline) and during administration of remifentanil at a target effect-site concentration of 2 ng ml−1 by target-controlled infusion. Analysis of systolic function focused on fractional area change (FAC). Analysis of diastolic function focused on peak early diastolic velocity of the mitral annulus (e′) and on transmitral peak flow velocity (E). Results Remifentanil infusion at a target concentration of 2 ng ml−1 did not affect heart rate or arterial pressure. There was no evidence of systolic or diastolic dysfunction during remifentanil infusion, as the echocardiographic measure of systolic function (FAC) was similar to baseline, and measures of diastolic function remained unchanged (e′) or improved slightly (E). Conclusion Continuous infusion of remifentanil in a clinically relevant concentration did not affect systolic and diastolic LV function in young healthy subjects during spontaneous breathing as indicated by TT
Frequency and causes of QRS prolongation during exercise electrocardiogram testing in biventricular paced patients with heart failure
Different effects of sevoflurane, desflurane, and isoflurane on early and late left ventricular diastolic function in young healthy adults†
Background Knowledge on the effects of volatile anaesthetics on left ventricular (LV) diastolic function in humans in vivo is limited. We tested the hypothesis that sevoflurane, desflurane, and isoflurane do not impair LV diastolic function in young healthy humans. Methods Sixty otherwise healthy subjects (aged 18-48 yr) undergoing minor procedures under general anaesthesia were studied. After randomization for the anaesthetic, transthoracic echocardiographic examinations were performed at baseline and under anaesthesia with 1 minimum alveolar concentration (MAC) of the volatile anaesthetics during spontaneous breathing and intermittent positive pressure ventilation (IPPV). Peak early (E′) and late (A′) diastolic velocities of the mitral annulus were studied as the main echocardiographic indicators of diastolic function. Results During anaesthesia with 1 MAC under spontaneous breathing, E′ increased with desflurane (P<0.001), was not significantly different with isoflurane (P=0.030), and decreased with sevoflurane (P=0.006). During IPPV, E′ was similar to baseline with desflurane (P=0.550), insignificantly decreased with isoflurane (P=0.029), and decreased with the sevoflurane group (P<0.001). In contrast, A′ was similarly reduced in all groups during spontaneous breathing without further changes during IPPV. Haemodynamic changes were comparable in all study groups. Conclusions The findings of this in vivo study indicate that desflurane and isoflurane, and most likely sevoflurane, have no relevant direct negative effect on early diastolic relaxation in young healthy humans. In contrast, all three volatile anaesthetics appear to impair late diastolic LV filling during atrial contraction. Trial Registration #: NCT002445
On-sky results of the adaptive optics MACAO for the new IR-spectrograph CRIRES at VLT
The adaptive optics MACAO has been implemented in 6 focii of the VLT
observatory, in three different flavors. We present in this paper the results
obtained during the commissioning of the last of these units, MACAO-CRIRES.
CRIRES is a high-resolution spectrograph, which efficiency will be improved by
a factor two at least for point-sources observations with a NGS brighter than
R=15. During the commissioning, Strehl exceeding 60% have been observed with
fair seeing conditions, and a general description of the performance of this
curvature adaptive optics system is done.Comment: SPIE conference 2006, Advances in adaptive optics, 12 pages, 11
figure
Quantum Cosmology and Higher-Order Lagrangian Theories
In this paper the quantum cosmological consequences of introducing a term
cubic in the Ricci curvature scalar into the Einstein--Hilbert action are
investigated. It is argued that this term represents a more generic
perturbation to the action than the quadratic correction usually considered. A
qualitative argument suggests that there exists a region of parameter space in
which neither the tunneling nor the no-boundary boundary conditions predict an
epoch of inflation that can solve the horizon and flatness problems of the big
bang model. This is in contrast to the --theory.Comment: 13 pages, LaTeX, preprint FERMILAB-Pub-94/XXX-A, March 199
Gravity as Backreaction
Quadratic theory of gravity is a complicated constraint system. We
investigate some consequences of treating quadratic terms perturbatively
(higher derivative version of backreaction effects). This approach is shown to
overcome some well known problems associated with higher derivative theories,
i.e., the physical gravitational degree of freedom remains unchanged from those
of Einstein gravity.
Using such an interpretation of gravity, we investigate a
classical and Wheeler DeWitt evolution of gravity for a
particular sign of , corresponding to non- tachyon case. Matter is
described by a phenomenological . It is concluded that
both the Friedmann potential () and the
Wheeler DeWitt potential () develop repulsive barriers near for
(i.e., ). The interpretations is clear. Repulsive
barrier in implies that a contracting FRW universe ()
will bounce to an expansion phase without a total gravitational collapse.
Repulsive barrier in means that is a classically forbidden
region. Therefore, probability of finding a universe with the big bang
singularity ( ) is exponentially suppressed.Comment: Accepted for publication in Phy. Rev. D.,18 pages, 6 figures, Latex
fil
Scaling solutions in general non-minimal coupling theories
A class of generalized non-minimal coupling theories is investigated, in
search of scaling attractors able to provide an accelerated expansion at the
present time. Solutions are found in the strong coupling regime and when the
coupling function and the potential verify a simple relation. In such cases,
which include power law and exponential functions, the dynamics is independent
of the exact form of the coupling and the potential. The constraint from the
time variability of , however, limits the fraction of energy in the scalar
field to less than 4% of the total energy density, and excludes accelerated
solutions at the present.Comment: 10 pages, 3 figures, accepted for publication in Phys. Rev.
- …