Nurture-U student mental health longitudinal survey: a study protocol

\ua9 Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY. Published by BMJ Group. INTRODUCTION: University life represents a critical period for young adults, providing opportunities for personal growth and development of coping skills but also posing significant mental health challenges. Recent trends indicate rising mental health concerns among university students, exacerbated by the COVID-19 pandemic and its aftermath. This study aims to address gaps in longitudinal data on student mental health in the UK and to identify risk and protective factors across diverse student populations. METHODS AND ANALYSIS: The current Nurture-U survey is developed from the U-Flourish biannual survey study piloted at Queen\u27s and Oxford universities in Canada and the UK, respectively. Nurture-U is a longitudinal survey study conducted at five UK universities, aiming to create a comprehensive data set from over 5000 students. The study will collect data at the start and completion of each academic year, using validated measures to assess well-being, mental health symptoms, lifestyle factors and access to support. Recruitment will target all students, with an emphasis on first-year students, to track their mental health trajectory from university entry through subsequent years. ETHICS AND DISSEMINATION: Ethical approval has been obtained from relevant committees at each participating university. Students will provide informed consent prior to participation, with risk messages and support information provided for those indicating self-harm or suicidal thoughts. Data will be de-identified and securely stored, with results disseminated through academic publications, social media and student engagement activities

Changes in quality of life following hypoglycaemia in adults with type 2 diabetes: A systematic review of longitudinal studies

AIM: To conduct a systematic review of published studies reporting on the longitudinal impacts of hypoglycaemia on quality of life (QoL) in adults with type 2 diabetes. METHOD: Database searches with no restrictions by language or date were conducted in MEDLINE, Cochrane Library, CINAHL and PsycINFO. Studies were included for review if they used a longitudinal design (e.g. cohort studies, randomised controlled trials) and reported on the association between hypoglycaemia and changes over time in patient-reported outcomes related to QoL. RESULTS: In all, 20 longitudinal studies published between 1998 and 2020, representing 50,429 adults with type 2 diabetes, were selected for review. A descriptive synthesis following Synthesis Without Meta-analysis guidelines indicated that self-treated symptomatic hypoglycaemia was followed by impairments in daily functioning along with elevated symptoms of generalised anxiety, diabetes distress and fear of hypoglycaemia. Severe hypoglycaemic events were associated with reduced confidence in diabetes self-management and lower ratings of perceived health over time. Frequent hypoglycaemia was followed by reduced energy levels and diminished emotional well-being. There was insufficient evidence, however, to conclude that hypoglycaemia impacted sleep quality, depressive symptoms, general mood, social support or overall diabetes-specific QoL. CONCLUSIONS: Longitudinal evidence in this review suggests hypoglycaemia is a common occurrence among adults with type 2 diabetes that impacts key facets in the physical and psychological domains of QoL. Nonetheless, additional longitudinal research is needed-in particular, studies targeting diverse forms of hypoglycaemia, more varied facets of QoL and outcomes assessed using hypoglycaemia-specific measures