13 research outputs found
Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017
- Author
- Abbasalizad-Farhangi M.
- Abbasi M.
- Abbastabar H.
- Abdelalim A.
- Abdoli A.
- Abdollahi M.
- Abdollahpour I.
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- Younis M.Z.
- Yousefi Z.
- Yousof H.-A.S.A.
- Yu C.
- Yusefzadeh H.
- Zahabi S.S.
- Zaki L.
- Zaman S.B.
- Zamani M.
- Zamanian M.
- Zandian H.
- Zarafshan H.
- Zepro N.B.
- Zerfu T.A.
- Zewale T.A.
- Zhang Y.
- Zhang Z.-J.
- Zhao X.-J.
- Zodpey S.
- Zomorodian K.
- Zotor F.B.
- �rnlöv J.
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Get PDFA double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4 (62.3 (55.1�70.8) million) to 6.4 (58.3 (47.6�70.7) million), but is predicted to remain above the World Health Organization�s Global Nutrition Target of <5 in over half of LMICs by 2025. Prevalence of overweight increased from 5.2 (30 (22.8�38.5) million) in 2000 to 6.0 (55.5 (44.8�67.9) million) children aged under 5 years in 2017. Areas most affected by double burden of malnutrition were located in Indonesia, Thailand, southeastern China, Botswana, Cameroon and central Nigeria. Our estimates provide a new perspective to researchers, policy makers and public health agencies in their efforts to address this global childhood syndemic. © 2020, The Author(s)
Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017 (Nature Medicine, (2020), 26, 5, (750-759), 10.1038/s41591-020-0807-6)
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Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017 (Nature Medicine, (2020), 26, 5, (750-759), 10.1038/s41591-020-0807-6)
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- Zandian H.
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- Zepro N.B.
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- Zhang Z.-J.
- Zhao X.-J.
- Zodpey S.
- Zomorodian K.
- Zotor F.B.
- �rnlöv J.
- Publication venue
- 'Springer Science and Business Media LLC'
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Get PDFAn amendment to this paper has been published and can be accessed via a link at the top of the paper. © 2020, The Author(s)
Transformerless quadratic‐based high step‐down DC–DC converter with wide duty cycle range
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- 'Institution of Engineering and Technology (IET)'
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No full textThe Value of Soluble Transferrin Receptor and Soluble Transferrin Receptor-ferritin Index in Discriminating Iron Deficiency Anaemia from Anaemia of Chronic Disease in Patients With Rheumatoid Arthritis
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No full textPrevalence and associated factors of suicidal ideation and attempt among undergraduate medical students of Haramaya University, Ethiopia. A cross sectional study
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- A. Adhikari
- A. Alem
- A. Derese
- A. Fekadu
- A. Goyal
- A. Pinzón-Amado
- A.L. Beautrais
- A.R. Torres
- B. Duko
- B. Gelaye
- D. Kebede
- E.S. Schernhammer
- F. Tang
- F. Younes
- Gelana Fekadu
- H.J. Simon
- Henock Asfaw
- J.M. Bertolote
- K. Sobowale
- K.I. McClelland
- L. Amiri
- L. Sun
- L. Van Niekerk
- L.N. Dyrbye
- L.N. Dyrbye
- L.N. Dyrbye
- M. Eskin
- M. Nyer
- M. Osama
- M. Pompili
- M. Pompili
- M. Pompili
- M. Yousaf
- M.J. Chikwande
- Marco Innamorati
- N. Izadinia
- Niguse Yigzaw
- O.S. Dalgard
- Organization W.H.
- P. Courtet
- P.F. Lovibond
- R. Coentre
- R. Coentre
- R.G. Menezes
- S. Ahmed
- S. Stack
- S.-M. Park
- S.N. Madu
- T. Gençöz
- T. Shibre
- T.D. Shanafelt
- T.L. Schwenk
- T.M. Fleming
- V. Miletic
- W. Chow
- W.A.W. Group
- Yadeta Alemayehu
- Z. Abdu
- Zegeye Yohannis
- Publication venue
- 'Public Library of Science (PLoS)'
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No full textTreatment of Melanoma and Nonmelanoma Skin Cancer
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- A. Hauschild
- A. Katalinic
- A. Schneeder
- A.C. Peterson
- A.M.M. Eggermont
- A.M.M. Eggermont
- A.S. Baldwin
- A.Y. Bedikian
- B. Berman
- B. Jansen
- B. Schuler-Thurner
- B.B. Noodt
- B.W. Hancock
- C. Garbe
- C. Thallinger
- C.M. Balch
- C.M. Balch
- D. Mathieu
- D. Schadendorf
- D. Strumberg
- D.L. Morton
- D.L. Morton
- E. Bajetta
- E. Stockfleth
- E. Tanghetti
- E.T. Creagan
- F. Belardelli
- F. Leo
- F.L. Lejeune
- G.C. Tucker
- G.Q. Phan
- H. Davies
- H. Helmbach
- H. Hurwitz
- H. Pehamberger
- H.J. Gogas
- H.S. Koops
- J. Locke
- J.A. Curtin
- J.A. Quinn
- J.A. Sosman
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- J.C. Becker
- J.C. Buchsbaum
- J.D. Wolchok
- J.E. Gershenwald
- J.E. Wolf
- J.F. Thompson
- J.J. Grob
- J.M. Kirkwood
- J.M. Kirkwood
- J.M. Kirkwood
- J.M. Thomas
- K. Margolin
- K. Rass
- K. Rass
- K. Wyman
- K.I. Amiri
- L. Serrone
- L. Tentori
- L.E. Rhodes
- L.Q. Chow
- L.R. Braathen
- M. Freeman
- M. Huncharek
- M. Pashenkov
- M. Ranson
- M. Ranson
- M. Stas
- M.F. Avril
- M.J. Reinhardt
- M.K. Silverman
- M.R. Middleton
- M.R. Thissen
- M.R. Thissen
- M.T. Ballo
- M.W. McCord
- N. Cascinelli
- N. Cascinelli
- N.P. Mendenhall
- O. Dormond
- O. Eton
- O.P. Isokangas
- P. Attia
- P. Boukamp
- P. Mohr
- P.B. Chapman
- R. Kaufinann
- R.I. Ceilly
- R.M. Szeimies
- S. Barranco
- S. Danson
- S. Danson
- S. Ugurel
- S. Verma
- S.A. Rosenberg
- S.E. Krown
- S.L. Wong
- S.M. Wilhelm
- S.S. Legha
- S.T. Tagawa
- T. Khansur
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- T.H. Guthrie Jr
- U. Reinhold
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- V.K. Sondak
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- W. Tilgen
- W.J. Hwu
- Y. Hu
- Y.M. Kirova
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2008
- Field of study
No full textImpact of methodological choices in comparative effectiveness studies: application in natalizumab versus fingolimod comparison among patients with multiple sclerosis
- Author
- Aalborg University
- Aalborg University Hospital
- Aarhus University
- Al-Amiri Hospital
- Al-Khedr A.
- Alfred Health
- Alroughani R.
- American University of Beirut
- Andersen J.B.
- Assistance publique - Hôpitaux de Marseille
- Assistance publique – Hôpitaux de Paris
- Azienda Ospedaliera Di Rilievo Nazionale San Giuseppe Moscati Avellino
- Ben Nasr Nasr H.
- Berger E.
- Bourre B.
- Boz C.
- Bramow S.
- Butzkueven H.
- Buzzard K.
- Cabre P.
- Camdessanché J.P.
- Casey R.
- Casez O.
- Centre Hospitalier de Pontoise
- Centre Hospitalier de Saint-Denis
- Centre Hospitalier de Versailles
- Centre Hospitalier Régional Universitaire de Tours
- Centre Hospitalier Sud Francilien
- Centre Hospitalier Universitaire d'Amiens Picardie
- Centre Hospitalier Universitaire de Fort de France
- Charles University
- CHI de Poissy-St-Germain-en-Laye
- CHU de Limoges
- CHU de Nancy
- CHU de Nantes
- CHU de Nice
- CHU de Nîmes
- CHU de Poitiers
- CHU de Rennes
- CHU de Toulouse
- CHU Hôpitaux de Rouen
- Ciron J.
- CISSS Chaudiere-Appalache
- Clavelou P.
- CNRS
- Csepany T.
- CSSS Saint-Jérôme
- De Sèze Seze J.
- Debouverie M.
- Defer G.
- Dimitri-Boulos D.
- Dokuz Eylul University
- Duquette P.
- Edan G.
- Eichau S.
- Eugene Devic EDMUS Foundation
- Ferraro D.
- Flinders University
- Frederiksen J.L.
- Gabriele d'Annunzio University
- Girard M.
- Gout O.
- Grammond P.
- Grand’Maison F.
- Granella F.
- Groupe hospitalier Pellegrin
- Hacettepe University
- Hankiewicz K.
- Hasselt University
- Havrdova E.K.
- Haydarpaşa Numune Training and Research Hospital
- Heinzlef O.
- Hilt Christensen Christensen C.C.
- Horakova D.
- Hospices civils de Lyon
- Hospital Universitario Virgen Macarena
- Hunter New England Health
- Hôpital du Bocage CHU Dijon Bourgogne
- Hôpital Fondation Adolphe de Rothschild
- Hôpital Gabriel Montpied
- Hôpital Gui de Chauliac
- Hôpital Henri Mondor
- Hôpital Jean Minjoz
- Hôpital Nord CHU de Saint-Étienne
- Hôpital Pontchaillou
- Institut national de la santé et de la recherche médicale
- IRCCS Istituto delle Scienze Neurologiche di Bologna
- Isfahan University of Medical Sciences
- Izquierdo G.
- Jensen M.B.
- Kalincik T.
- Karabudak R.
- Karadeniz Technical University
- Koch-Henriksen N.
- Labauge P.
- Laplaud D.A.
- Lebrun-Frenay C.
- Lechner-Scott J.
- Lefort M.
- Leray E.
- Lugaresi A.
- Magyari M.
- Maillart E.
- Maimone D.
- Mathiesen H.K.
- Maubeuge N.
- Maurousset A.
- McCombe P.
- Monash University
- Montcuquet A.
- Moreau T.
- Neuro Rive-Sud
- Nifle C.
- Ondokuz Mayis University
- Onofrj M.
- Ospedale Garibaldi
- Ozakbas S.
- Patti F.
- Pelletier J.
- Policlinico G Rodolico
- Pottier C.
- Prat A.
- Prevost J.
- Rasmussen P.V.
- Royal Brisbane & Women's Hospital
- Royal Melbourne Hospital
- Ruet A.
- Schreiber K.I.
- Sellebjerg F.
- Sharmin S.
- Shaygannejad V.
- Skibina O.
- Slee M.
- Soerensen P.S.
- Sola P.
- Sorbonne Université
- Spitaleri D.
- Stankoff B.
- Terzi M.
- Thouvenot E.
- Trojano M.
- Turkoglu R.
- Universite Claude Bernard Lyon 1
- Universite Joseph Fourier
- University Hospital of Northern Sealand
- University of Bari
- University of Bologna
- University of Catania
- University of Copenhagen
- University of Debrecen
- University of Melbourne
- University of Modena and Reggio Emilia
- University of Montreal
- University of Newcastle
- University of Parma
- University of Queensland
- Université de Caen
- Université de Lille
- Université de Strasbourg
- Van der Walt der Walt A.
- Van Wijmeersch Wijmeersch B.
- Vucic S.
- Vukusic S.
- Wahab A.
- Westmead Hospital
- Yamout B.
- Zephir H.
- Publication venue
- Figshare
- Publication date
- 01/01/2022
- Field of study
No full textAbstract Background Natalizumab and fingolimod are used as high-efficacy treatments in relapsing–remitting multiple sclerosis. Several observational studies comparing these two drugs have shown variable results, using different methods to control treatment indication bias and manage censoring. The objective of this empirical study was to elucidate the impact of methods of causal inference on the results of comparative effectiveness studies. Methods Data from three observational multiple sclerosis registries (MSBase, the Danish MS Registry and French OFSEP registry) were combined. Four clinical outcomes were studied. Propensity scores were used to match or weigh the compared groups, allowing for estimating average treatment effect for treated or average treatment effect for the entire population. Analyses were conducted both in intention-to-treat and per-protocol frameworks. The impact of the positivity assumption was also assessed. Results Overall, 5,148 relapsing–remitting multiple sclerosis patients were included. In this well-powered sample, the 95% confidence intervals of the estimates overlapped widely. Propensity scores weighting and propensity scores matching procedures led to consistent results. Some differences were observed between average treatment effect for the entire population and average treatment effect for treated estimates. Intention-to-treat analyses were more conservative than per-protocol analyses. The most pronounced irregularities in outcomes and propensity scores were introduced by violation of the positivity assumption. Conclusions This applied study elucidates the influence of methodological decisions on the results of comparative effectiveness studies of treatments for multiple sclerosis. According to our results, there are no material differences between conclusions obtained with propensity scores matching or propensity scores weighting given that a study is sufficiently powered, models are correctly specified and positivity assumption is fulfilled
Impact of methodological choices in comparative effectiveness studies: application in natalizumab versus fingolimod comparison among patients with multiple sclerosis
- Author
- Aalborg University
- Aalborg University Hospital
- Aarhus University
- Aix-Marseille Université
- Al-Amiri Hospital
- Al-Khedr A.
- Alfred Health
- Alroughani R.
- American University of Beirut
- Andersen J.B.
- Assistance publique – Hôpitaux de Paris
- Azienda Ospedaliera Di Rilievo Nazionale San Giuseppe Moscati Avellino
- Ben Nasr Nasr H.
- Berger E.
- Bourre B.
- Boz C.
- Bramow S.
- Butzkueven H.
- Buzzard K.
- Cabre P.
- Camdessanché J.P.
- Casey R.
- Casez O.
- Centre Hospitalier de Pontoise
- Centre Hospitalier de Saint-Denis
- Centre Hospitalier de Versailles
- Centre Hospitalier Régional Universitaire de Tours
- Centre Hospitalier Sud Francilien
- Centre Hospitalier Universitaire d'Amiens Picardie
- Centre Hospitalier Universitaire de Fort de France
- Charles University
- CHI de Poissy-St-Germain-en-Laye
- CHU de Bordeaux
- CHU de Nancy
- CHU de Nîmes
- CHU de Poitiers
- CHU de Rennes
- CHU de Saint-Étienne
- CHU de Toulouse
- CHU Hôpitaux de Rouen
- CHU Montpellier
- Ciron J.
- CISSS Chaudiere-Appalache
- Clavelou P.
- CNRS
- Csepany T.
- CSSS Saint-Jérôme
- De Sèze Seze J.
- Debouverie M.
- Defer G.
- Dimitri-Boulos D.
- Dokuz Eylul University
- Duquette P.
- Edan G.
- Eichau S.
- Eugene Devic EDMUS Foundation
- Ferraro D.
- Flinders University
- Frederiksen J.L.
- Gabriele d'Annunzio University
- Girard M.
- Gout O.
- Grammond P.
- Grand’Maison F.
- Granella F.
- Hacettepe University
- Hankiewicz K.
- Hasselt University
- Havrdova E.K.
- Haydarpaşa Numune Training and Research Hospital
- Heinzlef O.
- Hilt Christensen Christensen C.C.
- Horakova D.
- Hospices civils de Lyon
- Hospital Universitario Virgen Macarena
- Hunter New England Health
- Hôpital de Hautepierre
- Hôpital Dupuytren
- Hôpital Fondation Adolphe de Rothschild
- Hôpital Gabriel Montpied
- Hôpital Henri Mondor
- Hôpital Notre-Dame
- Institut national de la santé et de la recherche médicale
- IRCCS Istituto delle Scienze Neurologiche di Bologna
- Isfahan University of Medical Sciences
- Izquierdo G.
- Jensen M.B.
- Kalincik T.
- Karabudak R.
- Karadeniz Technical University
- Koch-Henriksen N.
- Labauge P.
- Laplaud D.A.
- Lebrun-Frenay C.
- Lechner-Scott J.
- Lefort M.
- Leray E.
- Lugaresi A.
- Magyari M.
- Maillart E.
- Maimone D.
- Mathiesen H.K.
- Maubeuge N.
- Maurousset A.
- McCombe P.
- Monash University
- Montcuquet A.
- Moreau T.
- Neuro Rive-Sud
- Nifle C.
- Ondokuz Mayis University
- Onofrj M.
- Ospedale Garibaldi
- Ozakbas S.
- Patti F.
- Pelletier J.
- Policlinico G Rodolico
- Pottier C.
- Prat A.
- Prevost J.
- Rasmussen P.V.
- Royal Brisbane and Women's Hospital
- Royal Melbourne Hospital
- Ruet A.
- Schreiber K.I.
- Sellebjerg F.
- Sharmin S.
- Shaygannejad V.
- Skibina O.
- Slee M.
- Soerensen P.S.
- Sola P.
- Spitaleri D.
- Stankoff B.
- Terzi M.
- Thouvenot E.
- Trojano M.
- Turkoglu R.
- Universite Claude Bernard Lyon 1
- Universite Joseph Fourier
- University Hospital of Montreal
- University Hospital of Northern Sealand
- University of Bari
- University of Bologna
- University of Catania
- University of Copenhagen
- University of Debrecen
- University of Melbourne
- University of Modena and Reggio Emilia
- University of Montreal
- University of Newcastle
- University of Parma
- University of Queensland
- Université Côte d'Azur
- Université de Bourgogne
- Université de Caen
- Université de Franche-Comté
- Université de Lille
- Université de Rennes
- Van der Walt der Walt A.
- Van Wijmeersch Wijmeersch B.
- Vucic S.
- Vukusic S.
- Wahab A.
- Westmead Hospital
- Yamout B.
- Zephir H.
- École des hautes études en santé publique
- Publication venue
- Figshare
- Publication date
- 01/01/2022
- Field of study
No full textAbstract Background Natalizumab and fingolimod are used as high-efficacy treatments in relapsing–remitting multiple sclerosis. Several observational studies comparing these two drugs have shown variable results, using different methods to control treatment indication bias and manage censoring. The objective of this empirical study was to elucidate the impact of methods of causal inference on the results of comparative effectiveness studies. Methods Data from three observational multiple sclerosis registries (MSBase, the Danish MS Registry and French OFSEP registry) were combined. Four clinical outcomes were studied. Propensity scores were used to match or weigh the compared groups, allowing for estimating average treatment effect for treated or average treatment effect for the entire population. Analyses were conducted both in intention-to-treat and per-protocol frameworks. The impact of the positivity assumption was also assessed. Results Overall, 5,148 relapsing–remitting multiple sclerosis patients were included. In this well-powered sample, the 95% confidence intervals of the estimates overlapped widely. Propensity scores weighting and propensity scores matching procedures led to consistent results. Some differences were observed between average treatment effect for the entire population and average treatment effect for treated estimates. Intention-to-treat analyses were more conservative than per-protocol analyses. The most pronounced irregularities in outcomes and propensity scores were introduced by violation of the positivity assumption. Conclusions This applied study elucidates the influence of methodological decisions on the results of comparative effectiveness studies of treatments for multiple sclerosis. According to our results, there are no material differences between conclusions obtained with propensity scores matching or propensity scores weighting given that a study is sufficiently powered, models are correctly specified and positivity assumption is fulfilled
Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017 (Nature Medicine, (2020), 26, 5, (750-759), 10.1038/s41591-020-0807-6)
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- Abbasi M.
- Abbastabar H.
- Abdelalim A.
- Abdoli A.
- Abdollahi M.
- Abdollahpour I.
- Abdulkader R.S.
- Abebe N.D.
- Abebo T.A.
- Abegaz K.H.
- Abolhassani H.
- Abreu L.G.
- Abrigo M.R.M.
- Abushouk A.I.
- Accrombessi M.M.K.
- Acharya D.
- Adabi M.
- Adebiyi A.O.
- Adedeji I.A.
- Adekanmbi V.
- Adema B.D.
- Adeoye A.M.
- Adetokunboh O.O.
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- Aduroja P.E.
- Advani S.M.
- Afarideh M.
- Afshin A.
- Aghaali M.
- Agrawal A.
- Ahmad T.
- Ahmadi K.
- Ahmadi S.
- Ahmed M.B.
- Ahmed R.
- Ajumobi O.
- Akal C.G.
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- Akinyemiju T.
- Akombi B.
- Al-Aly Z.
- Al-Mekhlafi H.M.
- Al-Raddadi R.M.
- Alam S.
- Alamene G.M.
- Alanzi T.M.
- Alema N.M.
- Ali B.A.
- Ali M.
- Alijanzadeh M.
- Alinia C.
- Alipour V.
- Alizade H.
- Aljunid S.M.
- Almasi A.
- Almasi-Hashiani A.
- Altirkawi K.
- Alvis-Guzman N.
- Alvis-Zakzuk N.J.
- Amare A.T.
- Amegah A.K.
- Amini S.
- Amiri F.
- Amit A.M.L.
- Anber N.H.
- Andrei C.L.
- Ansari F.
- Ansari-Moghaddam A.
- Anteneh Z.A.
- Antonio C.A.T.
- Antriyandarti E.
- Anvari D.
- Anwer R.
- Appiah S.C.Y.
- Arab-Zozani M.
- Arabloo J.
- Araya E.M.
- Arefi Z.
- Aremu O.
- Arnedo C.A.M.
- Arzani A.
- Asadi-Aliabadi M.
- Asadi-Pooya A.A.
- Asante K.O.
- Asgari S.
- Asghari B.
- Ashagre A.F.
- Asrat A.A.
- Ataeinia B.
- Atalay H.T.
- Atnafu D.D.
- Atout M.M.W.
- Ausloos M.
- Avokpaho E.F.G.A.
- Awasthi A.
- Ayanore M.A.
- Aynalem Y.A.A.
- Azadmehr A.
- Azari S.
- Azarian G.
- Azene Z.N.
- Babaee E.
- Badawi A.
- Badiye A.D.
- Bahrami M.A.
- Baig A.A.A.
- Bakhtiari A.
- Bakkannavar S.M.
- Balakrishnan S.
- Balalami N.J.
- Bali A.G.
- Banach M.
- Banik P.C.
- Baradaran-Seyed Z.
- Baraki A.G.
- Barboza M.A.
- Barua L.
- Basaleem H.
- Basu S.
- Bayati M.
- Bayih M.T.
- Baynes H.W.
- Bedi N.
- Behzadifar M.
- Behzadifar M.
- Bekele Y.A.
- Bennett D.A.
- Berbada D.A.
- Berhe A.K.
- Berhe K.
- Berman A.E.
- Bernstein R.S.
- Bhageerathy R.
- Bhandari D.
- Bharadwaj P.
- Bhattacharjee N.V.
- Bhattacharyya K.
- Bijani A.
- Bikbov B.
- Bilano V.
- Bililign N.
- Birara S.
- Birhane M.B.B.
- Birhanu M.
- Biswas R.K.
- Bitew Z.W.
- Bogale K.A.
- Bohlouli S.
- Bolla S.R.
- Boloor A.
- Borzouei S.
- Borzì A.M.
- Brady O.J.
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
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