Environmental and economic information for aggregates provision

This report describes a one-year research project entitled ‘Environmental and economic information systems for aggregates provision’. This project is an extension to previous research on Strategic Environmental Assessment (SEA) and future aggregates extraction, which was carried out by the British Geological Survey (BGS) and reported in early 2004 (Steadman, et al., 2004). Both phases of the research were co-funded by the BGS and the Mineral Industry Sustainable Technology Programme (MIST). Environmental, economic and social information are essential for sustainable planning for the provision of aggregates. There is a need to bring together disparate information relating to aggregate extraction. Datasets include the location of resources and their potential end-uses, as well as those on the environment and transport. Bringing this digital information together into one location or system will assist in supporting a more balanced and informed approach to the decision making process. A number of regulatory mechanisms are currently driving the gathering and compilation of relevant environmental, economic and social information. Current drivers for information relevant to aggregate provision include environmental appraisal of the provision of aggregates, SEA and Sustainability Appraisal (SA). The objective of this research was to provide an interactive ‘tool’ or information system for the minerals industry, land-use planners and other stakeholders to use when considering options for future aggregate provision. The study area for the research was the East Midlands Region of England. The project had three main deliverables: 1. To provide an online Geographic Information System (GIS) to access the ‘environmental sensitivity’ map which was developed for the East Midlands Region during the first phase of research; 2. to compile aggregate end-use suitability maps for the East Midland Region; and 3. to hold a stakeholder consultation exercise and dissemination seminars. Each of these was met within the agreed timeframe. The environmental sensitivity map information and associated attributes have been made available on the internet via the BGS ‘Minerals information online’ web GIS for the East Midlands Region (www.mineralsuk.com/web_gis). Accommodating these data in a web GIS environment has entailed some compromises on data resolution and system functionality. A methodology has been developed to integrate a range of aggregate technical property data. This can be used to summarise the distribution of aggregate resources suitable for particular end-uses. These summary technical data are useful in communicating issues of variable aggregate quality and economic value to non-technical stakeholders in the mineral planning process. Availability of appropriate technical property data for different aggregate resources across a wide geographical area is critical in developing these maps. Feedback from an extensive consultation and dissemination exercise has generally been very positive. Two critiques by independent consultants of the environmental sensitivity map were also undertaken. These were deemed an important aspect of the consultation process. Stakeholders raised several issues. There were some concerns about updating and maintenance of asset data and about the lack of social information. In addition, some fundamental issues of approach (particularly asset weighting) raised in the previous phase of this research resurfaced during this consultation. Environmental sensitivity mapping will be carried out for the whole of England by the BGS in the near future. The data will be made available online as each region becomes available. It is anticipated that the mineral GISs for all regions of England (except London) will be completed by December 2005. New datasets may be added to the environmental sensitivity layer as they become available. The research into end-use suitability maps will be carried on by the BGS under its Minerals Programme, with the support of co-funding where possible. The project team continue to welcome feedback and criticism of this research

Computational Nuclear Physics and Post Hartree-Fock Methods

We present a computational approach to infinite nuclear matter employing Hartree-Fock theory, many-body perturbation theory and coupled cluster theory. These lectures are closely linked with those of chapters 9, 10 and 11 and serve as input for the correlation functions employed in Monte Carlo calculations in chapter 9, the in-medium similarity renormalization group theory of dense fermionic systems of chapter 10 and the Green's function approach in chapter 11. We provide extensive code examples and benchmark calculations, allowing thereby an eventual reader to start writing her/his own codes. We start with an object-oriented serial code and end with discussions on strategies for porting the code to present and planned high-performance computing facilities.Comment: 82 pages, to appear in Lecture Notes in Physics (Springer), "An advanced course in computational nuclear physics: Bridging the scales from quarks to neutron stars", M. Hjorth-Jensen, M. P. Lombardo, U. van Kolck, Editor

Omega-Regular Model Checking

peer reviewed"Regular model checking" is the name of a family of techniques for analyzing infinite-state systems in which states are represented by words or trees, sets of states by finite automata on these objects, and transitions by finite automata operating on pairs of state encodings, i.e. finite-state transducers. In this context, the central problem is then to compute the iterative closure of a finite-state transducer. This paper addresses the use of regular model-checking like techniques for systems whose states are represented by infinite (omega) words. Its main motivation is to show the feasibility and usefulness of this approach through a combination of the necessary theoretical developments, implementation, and experimentation. The iteration technique that is used is adapted from recent work of the authors on the iteration of finite-word transducers. It proceeds by comparing successive elements of a sequence of approximations of the iteration, detecting an "increment" that is added to move from one approximation to the next, and extrapolating the sequence by allowing arbitrary repetitions of this increment. By restricting oneself to weak deterministic Buchi automata, and using a number of implementation optimizations, examples of significant size can be handled. The proposed transducer iteration technique can just as well be exploited to compute the closure of a given set of states by the transducer iteration, which has proven to be a very effective way of using the technique. Examples such as a leaking gas burner in which time is modeled by real variables have been handled completely within the automata-theoretic setting

Signatures of Relativistic Neutrinos in CMB Anisotropy and Matter Clustering

We present a detailed analytical study of ultra-relativistic neutrinos in cosmological perturbation theory and of the observable signatures of inhomogeneities in the cosmic neutrino background. We note that a modification of perturbation variables that removes all the time derivatives of scalar gravitational potentials from the dynamical equations simplifies their solution notably. The used perturbations of particle number per coordinate, not proper, volume are generally constant on superhorizon scales. In real space an analytical analysis can be extended beyond fluids to neutrinos. The faster cosmological expansion due to the neutrino background changes the acoustic and damping angular scales of the cosmic microwave background (CMB). But we find that equivalent changes can be produced by varying other standard parameters, including the primordial helium abundance. The low-l integrated Sachs-Wolfe effect is also not sensitive to neutrinos. However, the gravity of neutrino perturbations suppresses the CMB acoustic peaks for the multipoles with l>~200 while it enhances the amplitude of matter fluctuations on these scales. In addition, the perturbations of relativistic neutrinos generate a *unique phase shift* of the CMB acoustic oscillations that for adiabatic initial conditions cannot be caused by any other standard physics. The origin of the shift is traced to neutrino free-streaming velocity exceeding the sound speed of the photon-baryon plasma. We find that from a high resolution, low noise instrument such as CMBPOL the effective number of light neutrino species can be determined with an accuracy of sigma(N_nu) = 0.05 to 0.09, depending on the constraints on the helium abundance.Comment: 38 pages, 7 figures. Version accepted for publication in PR

Molecular cloning and transcriptional regulation of ompT , a ToxR-repressed gene in Vibrio cholerae

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72189/1/j.1365-2958.2000.01699.x.pd

Developing and Validating a New Multi-Dimensional Scale for Anti-Social Behaviour in a Higher Education Setting

The purpose of this research is to construct and validate a multi-dimensional scale of Anti-social Behaviour (hereafter ASB) in a Western higher education context (i.e. USA). To achieve this, four studies, each with a different sample, were performed. Study 1 (n = 150) followed an exploratory design to generate a pool of potential items measuring ASB. Study 2 (n = 254) explored the dimensionality of the items produced in Study 1 using Exploratory Factor Analysis (EFA) and reliability measures. Study 3 (n = 654) confirmed the factorial structure from Study 2 and assessed the measurement model invariance using structural equation modelling (SEM). Finally, Study 4 (n = 287) assessed the predictive validity of the ASB measure through testing a hypothetical path model linking ASB to narcissism and Machiavellianism via an SEM procedure. In total, our research findings conclude that the ASB measurement model is a two-factor multi-dimensional structure comprising: Interpersonal Antagonistic Behaviour (six items) as well as Indirect Distractive Behaviour (four items). The research and practical implications for universities are thereafter discussed

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types

Cosmic Microwave Background constraint on residual annihilations of relic particles

Energy injected into the Cosmic Microwave Background at redshifts z<10^6 will distort its spectrum permanently. In this paper we discuss the distortion caused by annihilations of relic particles. We use the observational bounds on deviations from a Planck spectrum to constrain a combination of annihilation cross section, mass, and abundance. For particles with (s-wave) annihilation cross section, =\sigma_0, the bound is f[(\sigma_0/6e-27cm^3/s)(\Omega_{X\bar{X}}h^2)^2]/(m_X/MeV)<0.2, where m_X is the particle mass, \Omega_{X\bar{X}} is the fraction of the critical density the particle and its antiparticle contribute if they survive to the present time, h=H_0/(100km/s/Mpc), H_0 is the Hubble constant, and f is the fraction of the annihilation energy that interacts electromagnetically. We also compute the less stringent limits for p-wave annihilation. We update other bounds on residual annihilations and compare them to our CMB bound.Comment: submitted to Phys. Rev.

Primary Invasive Aspergillosis of the Digestive Tract: Report of Two Cases and Review of the Literature

BACKGROUND: Disseminated aspergillosis is thought to occur as a result of vascular invasion from the lungs with subsequent bloodstream dissemination, and portals of entry other than sinuses and/or the respiratory tract remain speculative. METHODS: We report two cases of primary aspergillosis in the digestive tract and present a detailed review of eight of the 23 previously-published cases for which detailed data are available. RESULTS AND CONCLUSION: These ten cases presented with symptoms suggestive of typhlitis, with further peritonitis requiring laparotomy and small bowel segmental resection. All cases were characterized by the absence of pulmonary disease at the time of histologically-confirmed gastrointestinal involvement with vascular invasion by branched Aspergillus hyphae. These cases suggest that the digestive tract may represent a portal of entry for Aspergillus species in immunocompromised patients

All-sky search for long-duration gravitational wave transients with initial LIGO

We present the results of a search for long-duration gravitational wave transients in two sets of data collected by the LIGO Hanford and LIGO Livingston detectors between November 5, 2005 and September 30, 2007, and July 7, 2009 and October 20, 2010, with a total observational time of 283.0 days and 132.9 days, respectively. The search targets gravitational wave transients of duration 10-500 s in a frequency band of 40-1000 Hz, with minimal assumptions about the signal waveform, polarization, source direction, or time of occurrence. All candidate triggers were consistent with the expected background; as a result we set 90% confidence upper limits on the rate of long-duration gravitational wave transients for different types of gravitational wave signals. For signals from black hole accretion disk instabilities, we set upper limits on the source rate density between 3.4×10-5 and 9.4×10-4 Mpc-3 yr-1 at 90% confidence. These are the first results from an all-sky search for unmodeled long-duration transient gravitational waves. © 2016 American Physical Society