2,395 research outputs found
Electrogenic transport and K(+) ion channel expression by the human endolymphatic sac epithelium.
The endolymphatic sac (ES) is a cystic organ that is a part of the inner ear and is connected to the cochlea and vestibule. The ES is thought to be involved in inner ear ion homeostasis and fluid volume regulation for the maintenance of hearing and balance function. Many ion channels, transporters, and exchangers have been identified in the ES luminal epithelium, mainly in animal studies, but there has been no functional study investigating ion transport using human ES tissue. We designed the first functional experiments on electrogenic transport in human ES and investigated the contribution of K(+) channels in the electrogenic transport, which has been rarely identified, even in animal studies, using electrophysiological/pharmacological and molecular biological methods. As a result, we identified functional and molecular evidence for the essential participation of K(+) channels in the electrogenic transport of human ES epithelium. The identified K(+) channels involved in the electrogenic transport were KCNN2, KCNJ14, KCNK2, and KCNK6, and the K(+) transports via those channels are thought to play an important role in the maintenance of the unique ionic milieu of the inner ear fluid
Singlet superfield extension of the minimal supersymmetric standard model with Peccei-Quinn symmetry and a light pseudoscalar Higgs boson at the LHC
Motivated by the mu-problem and the axion solution to the strong CP-problem,
we extend the MSSM with one more chiral singlet field . The underlying
PQ-symmetry allows only one more term in the superpotential. The
spectrum of the Higgs system includes a light pseudoscalar (in addition
to the standard CP-even Higgs boson), predominantly decaying to two photons:
. Both Higgs bosons might be in the range accessible to
current LHC experiments.Comment: 5 pages with 3 figure
Fusion reaction of a weakly-bound nucleus with a deformed target
We discuss the role of deformation of the target nucleus in the fusion
reaction of the C + Th system at energies around the Coulomb
barrier, for which C is a well-known one-neutron halo nucleus. To this
end, we construct the potential between C and Th with the double
folding procedure, assuming that the projectile nucleus is composed of the core
nucleus, C, and a valance neutron. By taking into account the halo
nature of the projectile nucleus as well as the deformation of the target
nucleus, we simultaneously reproduce the fusion cross sections for the C
+ Th and the C + Th systems. Our calculation indicates
that the net effect of the breakup and the transfer channels is small for this
system.Comment: 7 pages, 5 figure
Coupled-channels analyses for Li + Pb fusion reactions with multi-neutron transfer couplings
We discuss the role of two-neutron transfer processes in the fusion reaction
of the Li + Pb systems. We first analyze the Li +
Pb reaction by taking into account the coupling to the Li +
Pb channel. To this end, we assume that two neutrons are directly
transferred to a single effective channel in Pb and solve the
coupled-channels equations with the two channels. By adjusting the coupling
strength and the effective -value, we successfully reproduce the
experimental fusion cross sections for this system. We then analyze the
Li + Pb reaction in a similar manner, that is, by taking into
account three effective channels with Li + Pb, Li +
Pb, and Li + Pb partitions. In order to take into account
the halo structure of the Li nucleus, we construct the potential between
Li and Pb with a double folding procedure, while we employ a
Wood-Saxon type potential with the global Aky\"uz-Winther parameters for the
other channels. Our calculation indicates that the multiple two-neutron
transfer process plays a crucial role in the Li + Pb fusion
reaction at energies around the Coulomb barrier
Lanczos exact diagonalization study of field-induced phase transition for Ising and Heisenberg antiferromagnets
Using an exact diagonalization treatment of Ising and Heisenberg model
Hamiltonians, we study field-induced phase transition for two-dimensional
antiferromagnets. For the system of Ising antiferromagnet the predicted
field-induced phase transition is of first order, while for the system of
Heisenberg antiferromagnet it is the second-order transition. We find from the
exact diagonalization calculations that the second-order phase transition
(metamagnetism) occurs through a spin-flop process as an intermediate step.Comment: 4 pages, 4 figure
Extended optical model analyses of Be+Au with dynamic polarization potentials
We discuss angular distributions of elastic, inelastic, and breakup cross
sections for Be + Au system, which were measured at energies
below and around Coulomb barrier.
To this end, we employ Coulomb dipole excitation (CDE) and long-range nuclear
(LRN) potential to take into account long range effects by halo nuclear system
and break up effects by weakly-bound structure. We then analyze recent
experimental data including 3-channes i.e. elastic, inelastic, and breakup
cross sections, at =29.6 MeV and =37.1 MeV.
From the extracted parameter sets using analysis, we successfully
reproduce the experimental angular distributions of the elastic, inelastic, and
breakup cross sections for Be+Au system simultaneously. Also we
discuss the necessity of LRN potential around Coulomb barrier from analyzed
experimental data
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