A study on the clinical, biochemical and hormonal profile of polycystic ovary syndrome patients attending tertiary care hospital

Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorder of reproductive age affecting 5% to 10% of women worldwide. It is a heterogenous, multifactorial, complex genetic disorder. PCOS receives a considerable attention because of its high prevalence and metabolic, reproductive and cardiovascular consequences.Methods: A cross sectional observation study of 100 PCOS patients was carried out between January 2014 to July 2015 in Gynaecology out-patient and Infertility OPD, Justice K. S. Hegde charitable hospital, Mangalore. The clinical, biochemical and hormonal profile of these patients were analysed and correlation was done between clinical features and biochemical and hormonal profile.Results: The prevalence of PCOS was 6.3% in the Gynaecology out-patient visits and 37.14% among infertile women. Menstrual irregularity was the most common complaint accounting for 31% followed by infertility (23%). Elevated leutinizing hormone and elevated LH: FSH was significant in irregular menstrual group. The prevalence of metabolic syndrome in our study was 21.3%. Spearmans correlation between various clinical and laboratory parameters showed menstrual cycle and body mass index(BMI) had a fair positive correlation and was significant. WHR (waist hip ratio) showed 21 times risk for metabolic syndrome.Conclusions: The study showed that most of our polycystic ovary syndrome subjects were hirsute, with central obesity and overweight or obese. Oligomenorrhea was the most common presentation. Among the various risk factors studied, WHR (waist hip ratio) showed 21 times risk for metabolic syndrome. Obese women with PCOS had more severe ovulatory dysfunction and need more attention for their appropriate management

A HYBRID CLOUD APPROACH FOR SECURE APPROVED DEDUPLICATION

Information Deduplication is one of imperative information pressure systems for wiping out copy duplicates of rehashing information, and has been generally utilized as a part of distributed storage to decrease the measure of storage room and spare data transmission. To secure the secrecy of touchy information while supporting Deduplication, the concurrent encryption system has been proposed to scramble the information before outsourcing. To better ensure information security, this methodology makes the main endeavor to formally address the issue of approved information Deduplication. Unique in relation to customary Deduplication frameworks, the differential benefits of clients are further considered in copy check other than the information itself. It likewise exhibit a few new Deduplication developments supporting approved copy check in a half and half cloud engineering. Security examination exhibits that our plan is secure as far as the definitions indicated in the proposed security model. As a proof of idea, we actualize a model of proposed approved copy check plan and direct testbed tests utilizing model. It demonstrates that proposed approved copy check plan brings about insignificant overhead contrasted with typical operations

Matter-Antimatter : An Accentuation-Attrition Model

A system of matter dissipating antimatter and parallel system of antimatter that contribute to the dissipation of the velocity of production of matter is investigated. It is shown that the time independence of the contributions portrays another system by itself and constitutes the equilibrium solution of the original time independent system. With the methodology reinforced with the explanations, we write the governing equations with the nomenclature for the systems in the foregoing, by concatenation process, ipso facto. We discuss following systems in all its predicational anteriorities, character consonations, ontological consonances, primordial exactitude, accolytish representation, differential relations, and concomitant contiguous similarities. (1) Antimatter as an integral part of the electromagnetic phenomena. (2) Electricity consists of the flow of electrons and positrons in opposite directions along a conductor (not only of electrons, as current accepted knowledge describes), induced by the crossing of a magnetic field through the conductor. (3) When a charged particle passes through matter at rest it will cause the production of electron pairs, that is, electrons and positrons, but if nothing separates them by force, they will reunite after the passing of the charged particle, nullifying each other, and the atoms of matter will be back at rest. (4) In order to preserve the law of conservation of energy, the amount of energy required to break free the electron and the positron from a bielectron (a theoretical dual particle containing an electron and a positron) must be equal to the amount of energy released by a matter-antimatter encounter of the same particles. (5) When a conductor is at rest all the bielectrons are located at their respective orbits in the conductor's atoms, generating no electric charge. (6) When a conductor is placed under a moving magnetic field, its otherwise stable bielectrons will break apart into electrons and positrons, which will flow in opposite directions along the conductor. At the closing of the circuit, electrons and positrons, attracted to each other by their opposite charge, reunite into bielectrons releasing an equal amount of energy as initially required to separate them. (7) Matter gormandizes antimatter (Antimatter has to pre-exist to be able to appear in a collision of particles. We are not creating antimatter; antimatter is there, intermingled with matter. Particle collisions do not “produce” antimatter; they separate antimatter from the particles of which it is part). (8) We assume that should there be another force in physics: the force of attraction between matter and antimatter and give a model. We shall call it Bundeswehr (German for "Federal Defense"). So Bundeswehr binds matter and antimatter. (9) At the closing of the circuit the free electrons and positrons, pushed forward by their own “pressure”, are irresistibly pulled by the attraction of their antimatter counterpart. It is this process of mutual attraction and continuous reunification into bielectrons which causes the flow of electrons and positrons along the conductors. Paper answers, not wholly or in full measure, but substantially the relationship between dark matter and antimatter and speculates in epiphenomena and phenomenological form the circumspective jurisprudence of consideration of the antimatter as dark matter. This also answers the long standing question in cosmology that why matter is prevalent in the universe in contrast to antimatter. The paper seems to confirm antimatter as an intrinsic constituent of ordinary matter; antimatter as an integral part of the electromagnetic phenomena; the existence of a new particle namely bielectron, consisting of an electron and a positron joined together within the atom; that matter and antimatter preceded the big-bang and their violent encounter may have been the actual cause of the big-bang itself; that matter and antimatter have a pacific coexistence in today’s universe, after the big-bang; the possible existence of a new force in physics namely Bundeswehr, which would recombine and keep matter and antimatter particles together. Keywords: matter-antimatter, where antimatter is, dark-matter, theory of electricity, bielectron, Big-Bang, origin of the Universe

Customer Satisfaction with Domestic Water Supply in India – A Study in Hubli city

Severe water crisis prevailed in twin Cities of Hubli-Dharwad in South India for a long time. During the last ten years, there has been considerable improvement in the water service. While most parts of the city is having intermittent supply system, a pilot 24/7 water service was implemented in a Demonstration Zone through the World Bank assistance, and State Government of Karnataka. The 24x7 project covers about 12 % of the total population of the city.  The objective of this paper is to study the customer satisfaction in both intermittent and 24/7 water service areas in Hubli city.  Stratified sampling method was adopted for four groups namely, low, medium, high income and backward classes namely the Scheduled Cast/Scheduled Tribes (SC/ST) groups.  The results of the study revealed that most customers in 24/7 demo zone were highly satisfied with water quality, continuity, quantity, and pressure; whereas there was slight dissatisfaction (12%) with regard to redressal of customer complaints. In contrast, there was considerable dissatisfaction with water quality, continuity and pressure in intermittent supply areas. There was universal opinion from both 24/7 demo zone and intermittent service areas supporting 24/7 water service scale up project in the city. Keywords: Intermittent Water Service, 24/7 Water Service, Customer Satisfactio

Aggressiveness of Ralstonia solanacearum isolates on Tomato

Bacterial wilt caused by Ralstonia solanacearum is the world’s most economically important destructive disease of crop plants. Fifty seven isolates of R. solanacearum causing wilt on different host plants were collected from different agro climatic zones of India of which 54 isolates were confirmed as race-1, biovar-3 and 3 isolates as race-1, biovar-3B based on morphological, physiological, biochemical and pathogenicity studies. All the isolates were authenticated as Ralstonia solanacearum by using two sets of primers (OLI1 & Y2 and Y1 & Y2). Serological identity of the isolates was done by using diagnostic kit obtained from International Potato Research Center, Lima, Peru and single chain variable fragment antibody specific to Ralstonia solanacearum. Fifty seven isolates of R. solanacearum were inoculated on tomato (Solanum Lycopersicum L) cv. Avinash-II under artificial conditions at bacterial concentration of 5x108 cfu/ml to test its aggressiveness; the results obtained are discussed in this paper

Acetyl salicylic acid augments functional recovery following sciatic nerve crush in mice

Cyclin-dependent kinase 5 (CDK-5) appears to play a significant role in peripheral nerve regeneration as CDK-5 inhibition retards nerve regeneration following nerve crush. Anti-inflammatory drug acetyl salicylic acid elevates CDK-5 and reduces ischemia – reperfusion injury in cultured neurons. In this study we have evaluated the effect of acetyl salicylic acid on functional recovery following sciatic nerve crush in mice. Eighteen Swiss albino mice underwent unilateral sciatic nerve crush. Test animals received acetyl salicylic acid (100 mg/kg/day, n = 6 or 50 mg/kg/day, n = 6) and control animals (n = 6) received normal saline for 14 days following surgery. Functional recovery was assessed with improvement in Sciatic Function Index, nociception and gait. In comparison with normal saline treatment, acetyl salicylic acid (100 mg/kg/day) significantly improved functional recovery following sciatic nerve crush. Anti-inflammatory drug acetyl salicylic acid appears to be a promising agent for treating peripheral nerve injuries and hence elucidation of its neuroprotective pathways is necessary