692 research outputs found
A new wireless underground network system for continuous monitoring of soil water contents
A new stand-alone wireless embedded network system has been developed recently for continuous monitoring of soil water contents at multiple depths. This paper presents information on the technical aspects of the system, including the applied sensor technology, the wireless communication protocols, the gateway station for data collection, and data transfer to an end user Web page for disseminating results to targeted audiences. Results from the first test of the network system are presented and discussed, including lessons learned so far and actions to be undertaken in the near future to improve and enhance the operability of this innovative measurement approac
Nuclear structure studies with the 7Li(e,e'p) reaction
Experimental momentum distributions for the transitions to the ground state
and first excited state of 6He have been measured via the reaction
7Li(e,e'p)6He, in the missing momentum range from -70 to 260 MeV/c. They are
compared to theoretical distributions calculated with mean-field wave functions
and with variational Monte Carlo (VMC) wave functions which include strong
state-dependent correlations in both 7Li and 6He. These VMC calculations
provide a parameter-free prediction of the momentum distribution that
reproduces the measured data, including its normalization. The deduced summed
spectroscopic factor for the two transitions is 0.58 +/- 0.05, in perfect
agreement with the VMC value of 0.60. This is the first successful comparison
of experiment and ab initio theory for spectroscopic factors in p-shell nuclei.Comment: 4 pages, 3 figure
Jastrow-type calculations of one-nucleon removal reactions on open - shell nuclei
Single-particle overlap functions and spectroscopic factors are calculated on
the basis of Jastrow-type one-body density matrices of open-shell nuclei
constructed by using a factor cluster expansion. The calculations use the
relationship between the overlap functions corresponding to bound states of the
-particle system and the one-body density matrix for the ground state of
the -particle system. In this work we extend our previous analyses of
reactions on closed-shell nuclei by using the resulting overlap functions for
the description of the cross sections of reactions on the open -
shell nuclei Mg, Si and S and of S
reaction. The relative role of both shell structure and short-range
correlations incorporated in the correlation approach on the spectroscopic
factors and the reaction cross sections is pointed out.Comment: 11 pages, 5 figures, to be published in Phys. Rev.
Spontaneous Branching of Anode-Directed Streamers between Planar Electrodes
Non-ionized media subject to strong fields can become locally ionized by
penetration of finger-shaped streamers. We study negative streamers between
planar electrodes in a simple deterministic continuum approximation. We observe
that for sufficiently large fields, the streamer tip can split. This happens
close to Firsov's limit of `ideal conductivity'. Qualitatively the tip
splitting is due to a Laplacian instability quite like in viscous fingering.
For future quantitative analytical progress, our stability analysis of planar
fronts identifies the screening length as a regularization mechanism.Comment: 4 pages, 6 figures, submitted to PRL on Nov. 16, 2001, revised
version of March 10, 200
Tips for implementing multigrid methods on domains containing holes
As part of our development of a computer code to perform 3D `constrained
evolution' of Einstein's equations in 3+1 form, we discuss issues regarding the
efficient solution of elliptic equations on domains containing holes (i.e.,
excised regions), via the multigrid method. We consider as a test case the
Poisson equation with a nonlinear term added, as a means of illustrating the
principles involved, and move to a "real world" 3-dimensional problem which is
the solution of the conformally flat Hamiltonian constraint with Dirichlet and
Robin boundary conditions. Using our vertex-centered multigrid code, we
demonstrate globally second-order-accurate solutions of elliptic equations over
domains containing holes, in two and three spatial dimensions. Keys to the
success of this method are the choice of the restriction operator near the
holes and definition of the location of the inner boundary. In some cases (e.g.
two holes in two dimensions), more and more smoothing may be required as the
mesh spacing decreases to zero; however for the resolutions currently of
interest to many numerical relativists, it is feasible to maintain second order
convergence by concentrating smoothing (spatially) where it is needed most.
This paper, and our publicly available source code, are intended to serve as
semi-pedagogical guides for those who may wish to implement similar schemes.Comment: 18 pages, 11 figures, LaTeX. Added clarifications and references re.
scope of paper, mathematical foundations, relevance of work. Accepted for
publication in Classical & Quantum Gravit
Assessing the prognostic value of tumor-infiltrating CD57+ cells in advanced stage head and neck cancer using QuPath digital image analysis
This study aimed to assess the prognostic value of intratumoral CD57+ cells in head and neck squamous cell carcinoma (HNSCC) and to examine the reproducibility of these analyses using QuPath. Pretreatment biopsies of 159 patients with HPV-negative, stage III/IV HNSCC treated with chemoradiotherapy were immunohistochemically stained for CD57. The number of CD57+ cells per mm2 tumor epithelium was quantified by two independent observers and by QuPath, software for digital pathology image analysis. Concordance between the observers and QuPath was assessed by intraclass correlation coefficients (ICC). The correlation between CD57 and clinicopathological characteristics was assessed; associations with clinical outcome were estimated using Cox proportional hazard analysis and visualized using Kaplan-Meier curves. The patient cohort had a 3-year OS of 65.8% with a median follow-up of 54 months. The number of CD57+ cells/mm2 tumor tissue did not correlate to OS, DFS, or LRC. N stage predicted prognosis (OS: HR 0.43, p = 0.008; DFS: HR 0.41, p = 0.003; LRC: HR 0.24, p = 0.007), as did WHO performance state (OS: HR 0.48, p = 0.028; LRC: 0.33, p = 0.039). Quantification by QuPath showed moderate to good concordance with two human observers (ICCs 0.836, CI 0.805–0.863, and 0.741, CI 0.692–0.783, respectively). In conclusion, the presence of CD57+ TILs did not correlate to prognosis in advanced stage, HPV-negative HNSCC patients treated with chemoradiotherapy. Substantial concordance between human observers and QuPath was found, confirming a promising future role for digital, algorithm driven image analysis
Two-dimensional turbulence in magnetised plasmas
In an inhomogeneous magnetised plasma the transport of energy and particles
perpendicular to the magnetic field is in general mainly caused by quasi
two-dimensional turbulent fluid mixing. The physics of turbulence and structure
formation is of ubiquitous importance to every magnetically confined laboratory
plasma for experimental or industrial application. Specifically, high
temperature plasmas for fusion energy research are also dominated by the
properties of this turbulent transport. Self-organisation of turbulent vortices
to mesoscopic structures like zonal flows is related to the formation of
transport barriers that can significantly enhance the confinement of a fusion
plasma. This subject of great importance in research is rarely touched on in
introductory plasma physics or continuum dynamics courses. Here a brief
tutorial on 2D fluid and plasma turbulence is presented as an introduction to
the field, appropriate for inclusion in undergraduate and graduate courses.Comment: This is an author-created, un-copyedited version of an article
published in European Journal of Physics. IOP Publishing Ltd is not
responsible for any errors or omissions in this version of the manuscript or
any version derived from it. The definitive publisher authenticated version
is available online at doi: 10.1088/0143-0807/29/5/00
A Summary of the Inaugural WHO Classification of Pediatric Tumors: Transitioning from the Optical into the Molecular Era
Pediatric tumors are uncommon, yet are the leading cause of cancer-related death in childhood. Tumor types, molecular characteristics, and pathogenesis are unique, often originating from a single genetic driver event. The specific diagnostic challenges of childhood tumors led to the development of the first World Health Organization (WHO) Classification of Pediatric Tumors. The classification is rooted in a multilayered approach, incorporating morphology, IHC, and molecular characteristics. The volume is organized according to organ sites and provides a single, state-of-the-art compendium of pediatric tumor types. A special emphasis was placed on “blastomas,” which variably recapitulate the morphologic maturation of organs from which they originate
An aCGH classifier derived from BRCA1-mutated breast cancer and benefit of high-dose platinum-based chemotherapy in HER2-negative breast cancer patients
Background: Breast cancer cells deficient for BRCA1 are hypersensitive to agents inducing DNA double-strand breaks (DSB), such as bifunctional alkylators and platinum agents. Earlier, we had developed a comparative genomic hybridisation (CGH) classifier based on BRCA1-mutated breast cancers. We hypothesised that this BRCA1-likeCGH classifier could also detect loss of function of BRCA1 due to other causes besides mutations and, consequently, might predict sensitivity to DSB-inducing agents
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