Structure, electrochemical properties and functionalization of amorphous CN films deposited by femtosecond pulsed laser ablation

Amorphous carbon nitride (a-C:N) material has attracted much attention in research and development. Recently, it has become a more promising electrode material than conventional carbon based electrodes in electrochemical and biosensor applications. Nitrogen containing amorphous carbon (a-C:N) thin films have been synthesized by femtosecond pulsed laser deposition (fs-PLD) coupled with plasma assistance through Direct Current (DC) bias power supply. During the deposition process, various nitrogen pressures (0 to 10 Pa) and DC bias (0 to ¿ 350 V) were used in order to explore a wide range of nitrogen content into the films. The structure and chemical composition of the films have been studied by using Raman spectroscopy, electron energy-loss spectroscopy (EELS) and high-resolution transmission electron microscopy (HRTEM). Increasing the nitrogen pressure or adding a DC bias induced an increase of the N content, up to 21 at.%. Nitrogen content increase induces a higher sp2 character of the film. However DC bias has been found to increase the film structural disorder, which was detrimental to the electrochemical properties. Indeed the electrochemical measurements, investigated by cyclic voltammetry (CV), demonstrated that a-C:N film with moderate nitrogen content (10 at.%) exhibited the best behavior, in terms of reversibility and electron transfer kinetics. Electrochemical grafting from diazonium salts was successfully achieved on this film, with a surface coverage of covalently bonded molecules close to the dense packed monolayer of ferrocene molecules. Such a film may be a promising electrode material in electrochemical detection of electroactive pollutants on bare film, and of biopathogen molecules after surface grafting of the specific affinity receptor.This work is produced with the financial support of the Future Program Lyon Saint-Etienne (PALSE) from the University of Lyon (ANR-11-IDEX-0007), under the “Investissements d'Avenir” program managed by the National Agency Research (ANR)

Consistent And Regularized Magnification Of Images

Because more output data must be created than is available from the input, magnification is an III-posed problem. Traditional magnification relies on resampling an interpolation model at the appropriate rate; unfortunately, this simple solution is blind to the presence of the analog fitter that was implicity present when the samples of the function to be magnified were acquired. Consistent resampling has been introduced to take this into account, but it turns out that this solution is still under-constrained. In this paper, we propose regularization as a way to devise a deterministic magnification method that fully satisfies consistency constraints in the absence of noise, and at the same time that produces and output that best fulfilled a wide class of criteria for regularity. Contrarily to many other methods, ours has been designed without ever leaving the continuous domain. We conduct experiments that show the benefit of our approach

Synthesis of Vanadium oxides by Pulsed Laser Deposition and Rapid thermal annealing

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Thermally Activated Resonant Grating using Vanadium Dioxyde Synthetized by Pulsed Laser Deposition

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Pyridinic dominance nitrogen doped graphene by femtosecond pulsed laser deposition

International audienceCarbon-based materials represent an attractive prospective in fuel cell, electrochemical and biosensors applications [1]. Recently, nitrogen doped carbon materials have raised attention in research and development to enhance their practical applications. Especially, the direct controllable nitrogen doping in graphene synthesis routes have been an attracting area of research in catalysis and sensor applications [2,3]. Here, we present the direct growth of N doped graphene from ultrashort-pulsed laser deposition technique, based on previous works related to direct synthesis of graphene [4]. The N doped graphene has been synthesized by femtosecond pulsed laser deposition and characterized by different characterization techniques to study microstructural, surface morphology and chemical bonding information. The Multi-wavelength Raman spectroscopy confirms the doping in graphene network. The nitrogen doping in graphene decreases the 2D band intensity and the correlation length. The Raman mapping has confirmed the homogenous doping of nitrogen in the graphene network. By doping, the G peak is blue shifted by 4 cm-1 and the 2D peak is red shifted by 5 cm-1; which corresponds to the n-type doping behaviour and could open a bandgap in the graphene. The surface morphology has been studied by Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM). The films shows the layered type structures and the low roughness values were estimated in both graphene and N doped graphene. The chemical composition and bonding have been studied by X-ray Photoelectron Spectroscopy (XPS), the nitrogen doping was estimated 3 at.%. The C1s spectra shifted to higher binding energy and the N1s spectra revealed three bonding structures, which are assigned to pyridinic-N, pyrrolic-N and graphitc-N type. The pyridinic-N dominance is high in our N doped graphene. The pyridinic-N dominance N doped graphene is attractive as a catalyst in Oxygen Reduction Reactions (ORR) to enhance their applications in fuel cells and electrochemical sensors. Compared to other carbon-based electrodes, N doped graphene will be a better electrode in electrochemical sensors. It can be used for the detection of hazardous pollutants and bio-pathogens at low concentrations.References(1) Fortgang, P.; Tite, T.; Barnier, V.; Zehani, N.; Maddi, C.; Lagarde, F.; Loir, A.-S.; Jaffrezic-Renault, N.; Donnet, C.; Garrelie, F.; et al. Robust Electrografting on Self-Organized 3D Graphene Electrodes. ACS Appl. Mater. Interfaces 2016, 8, 1424–1433.(2) Wu, J.; Ma, L.; Yadav, R. M.; Yang, Y.; Zhang, X.; Vajtai, R.; Lou, J.; Ajayan, P. M. Nitrogen-Doped Graphene with Pyridinic Dominance as a Highly Active and Stable Electrocatalyst for Oxygen Reduction. ACS Appl. Mater. Interfaces 2015, 7, 14763–14769.(3) Wang, Y.; Shao, Y.; Matson, D. W.; Li, J.; Lin, Y. Nitrogen-Doped Graphene and Its Application in Electrochemical Biosensing. ACS Nano 2010, 4, 1790–1798.(4) Tite, T.; Donnet, C.; Loir, A.-S.; Reynaud, S.; Michalon J.-Y.; Vocanson, F.; Garrelie, F.; Graphene-based textured surface by pulsed laser deposition as a robust platform forsurface enhanced Raman scattering applications. Applied Physics Letters 104 (2014) 041912-1 – 0419012-4

Standards to support information systems integration in anatomic pathology

CONTEXT: Integrating anatomic pathology information- text and images-into electronic health care records is a key challenge for enhancing clinical information exchange between anatomic pathologists and clinicians. The aim of the Integrating the Healthcare Enterprise (IHE) international initiative is precisely to ensure interoperability of clinical information systems by using existing widespread industry standards such as Digital Imaging and Communication in Medicine (DICOM) and Health Level Seven (HL7). OBJECTIVE: To define standard-based informatics transactions to integrate anatomic pathology information to the Healthcare Enterprise. DESIGN: We used the methodology of the IHE initiative. Working groups from IHE, HL7, and DICOM, with special interest in anatomic pathology, defined consensual technical solutions to provide end-users with improved access to consistent information across multiple information systems. RESULTS: The IHE anatomic pathology technical framework describes a first integration profile, "Anatomic Pathology Workflow," dedicated to the diagnostic process including basic image acquisition and reporting solutions. This integration profile relies on 10 transactions based on HL7 or DICOM standards. A common specimen model was defined to consistently identify and describe specimens in both HL7 and DICOM transactions. CONCLUSION: The IHE anatomic pathology working group has defined standard-based informatics transactions to support the basic diagnostic workflow in anatomic pathology laboratories. In further stages, the technical framework will be completed to manage whole-slide images and semantically rich structured reports in the diagnostic workflow and to integrate systems used for patient care and those used for research activities (such as tissue bank databases or tissue microarrayers)

La co-conception en Living Lab santé et autonomie 1 - Concepts, méthodes et outils

International audienceLa période récente a vu la multiplication des « Living Labs » , structures visant à faire travailler ensemble des acteurs différents dans leurs compétences et objectifs individuels, y compris l’usager final, pour concevoir, développer, mettre en oeuvre et évaluer des solutions innovantes.Ce livre présente un travail associant les acteurs de terrain et académiques sur la co-conception dans les Living Labs santé et autonomie (LLSA). Il précise des lignes communes et des bonnes pratiques malgré leur diversité. Cette connaissance des LLSA permet de comprendre leur capacité à soutenir un développement efficient de cette forme de conception pour les acteurs de la santé et de l’autonomie, l’industrie et les investisseurs.La co-conception en Living Lab santé et autonomie 1 donne ainsi une meilleure visibilité et lisibilité de ces nouveaux acteurs. Ce premier ouvrage examine les concepts, méthodes et outils des LLSA. Il s’appuie sur leur expérience et le regard d’experts pour éclairer leur mise en oeuvre. Le coordonnateur - Ingénieur général des Mines, docteur en sciences de gestion, cofondateur du forum LLSA, Robert Picard est également référent santé du conseil général de l'économie au ministère de l'Economie. Il est l'auteur de nombreux rapports sur la valeur des technologies en santé

La co-conception en Living Lab santé et autonomie 1 - Concepts, méthodes et outils

International audienceLa période récente a vu la multiplication des « Living Labs » , structures visant à faire travailler ensemble des acteurs différents dans leurs compétences et objectifs individuels, y compris l’usager final, pour concevoir, développer, mettre en oeuvre et évaluer des solutions innovantes.Ce livre présente un travail associant les acteurs de terrain et académiques sur la co-conception dans les Living Labs santé et autonomie (LLSA). Il précise des lignes communes et des bonnes pratiques malgré leur diversité. Cette connaissance des LLSA permet de comprendre leur capacité à soutenir un développement efficient de cette forme de conception pour les acteurs de la santé et de l’autonomie, l’industrie et les investisseurs.La co-conception en Living Lab santé et autonomie 1 donne ainsi une meilleure visibilité et lisibilité de ces nouveaux acteurs. Ce premier ouvrage examine les concepts, méthodes et outils des LLSA. Il s’appuie sur leur expérience et le regard d’experts pour éclairer leur mise en oeuvre. Le coordonnateur - Ingénieur général des Mines, docteur en sciences de gestion, cofondateur du forum LLSA, Robert Picard est également référent santé du conseil général de l'économie au ministère de l'Economie. Il est l'auteur de nombreux rapports sur la valeur des technologies en santé

Direct Synthesis of Nitrogen Doped Graphene by Ultrashort Pulsed Laser Deposition

International audienceGraphene and doped graphene materials new synthesis routes are an attractive prospective. Especially, nitrogen doping has been an effective way to tailor the properties of graphene and make them attractive in a wide range of potential applications [1]. Recently, pulsed laser deposition of graphene has been shown to be effective in electrochemistry and biosensors applications [2]. This work reports graphene and N-doped graphene synthesis by femtosecond pulsed laser deposition. The nitrogen doping and structural changes have been studied systematically by various characterization techniques. The X-ray photoelectron spectroscopy has been performed to elucidate the C-N bonding information and N content in doped graphene. Doping of graphene decreased the 2D peak intensity compared to the pure graphene, and Raman mapping confirmed that the doping is homogeneous. The crystalline size (La) of N-doped graphene decreased with doping. The N atoms are evidenced by XPS to mainly pyridinic-N type nitrogen structure, with a N doping content up to 3 at.%. The surface morphology of films was studied by Scanning electron microscopy and Atomic force microscopy. This simple, fast and low temperature approach offers directly pyridinic-type of N bonding with high N content. This type of grown N-doped graphene could be a promising material in electrochemical sensors, electrochemical energy devices, bioelectronics and biosensors applications