Chemical composition and antimicrobial activity of propolis collected from some localities of Western Algeria

The chemical analysis and antibacterial activity of propolis collected from some parts of Western Algeria were investigated. The ethanolic extracts of propolis (EEP) were evaluated for further investigation. The major constituents in EEP were identified by high-performance liquid chromatography (HPLC) analysis. All EEP samples were active against Gram positive bacteria (Staphylococcus aureus, Bacillus subtilis, Bacillus cereus), but no activity was found against Gram negative bacteria (Pseudomonas aeruginosa, Escherichia coli). The mean diameters of growth inhibition of the EEP ranged between 8.05 and 21.4 mm. The propolis extract obtained from Sidi bel Abbés (SFS-SBA) was more active than other samples as well as showed unique HPLC profile. These results support the idea that propolis can be a promising natural food preservative in food industry and alternative candidate for management of bacterial infections caused by drug-resistant microorganisms

Extension and its characteristics of ECRH plasma in the LHD

One of the main objectives of the LHD is to extend the plasma confinement database for helical systems and to demonstrate such extended plasma confinement properties to be sustained in steady state. Among the various plasma parameter regimes, the study of confinement properties in the collisionless regime is of particular importance. Electron cyclotron resonance heating (ECRH) has been extensively used for these confinement studies of the LHD plasma from the initial operation. The system optimizations including the modification of the transmission and antenna system are performed with the special emphasis on the local heating properties. As the result, central electron temperature of more than 10 keV with the electron density of 0.6 x 10$^{19}$ m$^{-3}$ is achieved near the magnetic axis. The electron temperature profile is characterized by a steep gradient similar to those of an internal transport barrier observed in tokamaks and stellarators. 168 GHz ECRH system demonstrated efficient heating at over the density more than 1.0 x 10$^{20}$ m$^{-3}$. CW ECRH system is successfully operated to sustain 756 s discharge.Comment: 12th International Congress on Plasma Physics, 25-29 October 2004, Nice (France

The observation of nonlinear ion cyclotron wave excitation during high-harmonic fast wave heating in the large helical device

A wave detector, a newly designed magnetic probe, is installed in the large helical device (LHD). This wave detector is a 100-turn loop coil with electrostatic shield. Comparing a one-loop coil to this detector, this detector has roughly constant power coupling in the lower frequency range of40 MHz, and it can easily detect magnetic wave in the frequency of a few megahertz. During high-harmonic fast wave heating, lower frequency waves (<10 MHz) were observed in the LHD for the first time, and for the power density threshold of lower frequency wave excitation (7.5 MHz) the power density of excited pumped wave (38.47 MHz) was approximately ?46 dBm/Hz. Theselower frequencies are kept constant for electron density and high energy particle distribution, and these lower frequency waves seem to be ion cyclotron waves caused by nonlinear wave-particle interaction, for example, parametric decay instability

A Thirty Million Year-Old Inherited Heteroplasmy

Due to essentially maternal inheritance and a bottleneck effect during early oogenesis, newly arising mitochondrial DNA (mtDNA) mutations segregate rapidly in metazoan female germlines. Consequently, heteroplasmy (i.e. the mixture of mtDNA genotypes within an organism) is generally resolved to homoplasmy within a few generations. Here, we report an exceptional transpecific heteroplasmy (predicting an alanine/valine alloacceptor tRNA change) that has been stably inherited in oniscid crustaceans for at least thirty million years. Our results suggest that this heteroplasmy is stably transmitted across generations because it occurs within mitochondria and therefore escapes the mtDNA bottleneck that usually erases heteroplasmy. Consistently, at least two oniscid species possess an atypical trimeric mitochondrial genome, which provides an adequate substrate for the emergence of a constitutive intra-mitochondrial heteroplasmy. Persistence of a mitochondrial polymorphism on such a deep evolutionary timescale suggests that balancing selection may be shaping mitochondrial sequence evolution in oniscid crustaceans

Preparation of amino-substituted indenes and 1,4-dihydronaphthalenes using a one-pot multireaction approach: total synthesis of oxybenzo[c]phenanthridine alkaloids

Allylic trichloroacetimidates bearing a 2-vinyl or 2-allylaryl group have been designed as substrates for a one-pot, two-step multi-bond-forming process leading to the general preparation of aminoindenes and amino-substituted 1,4-dihydronaphthalenes. The synthetic utility of the privileged structures formed from this one-pot process was demonstrated with the total synthesis of four oxybenzo[c]phenanthridine alkaloids, oxychelerythrine, oxysanguinarine, oxynitidine, and oxyavicine. An intramolecular biaryl Heck coupling reaction, catalyzed using the Hermann–Beller palladacycle was used to effect the key step during the synthesis of the natural products